Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Exploring Baltic Sea cyanobacteria for small-molecule inhibitors of microRNA function

2017/25/B/NZ9/00202

Keywords:

cyanobacteria luciferase reporter cell line microRNA small-molecule inhibitors

Descriptors:

  • NZ9_9: Environmental biotechnology
  • NZ8_6: Marine biology

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Geoinżynierii

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Paweł Brzuzan 

Number of co-investigators in the project: 8

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 410 100 PLN

Project start date (Y-m-d): 2018-02-06

Project end date (Y-m-d): 2022-02-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Automatyczny licznik komórek (18 500 PLN)
  2. Inkubator CO2 do badań cytotoksyczności (40 000 PLN)
  3. Inkubator CO2 z chłodzeniem (60 000 PLN)
  4. Termocykler do Real-Time PCR (160 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Biological Activity and Stability of Aeruginosamides from Cyanobacteria
    Authors:
    Marta Cegłowska, Patrycja Kwiecień, Karolina Szubert, Paweł Brzuzan, Maciej Florczyk, Christine Edwards, Alicja Kosakowska, Hanna Mazur-Marzec
    Academic press:
    Marine Drugs (rok: 2021, tom: 20(2), strony: 93), Wydawca: MDPI MDPI Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/md20020093 - link to the publication
  2. CyanoMetDB, a comprehensive public database of secondary metabolites from cyanobacteria
    Authors:
    Jones, M.R.; Pinto, E.; Torres, M.A.; Dörr, F.; Mazur-Marzec, H.; Szubert, K.; Tartaglione, L.; Dell'Aversano, C.; Miles C.O.; Beach, D.G.;McCarron, P.; Sivonen, K.; Fewer, D.P.; Jokela, J.; Janssen, E.M-L
    Academic press:
    Water Research (rok: 2021, tom: 196, strony: 117017), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.watres.2021.117017 - link to the publication
  3. Luciferase reporter assay for small-molecule inhibitors of MIR92b-3p function: Screening cyanopeptolins produced by Nostoc from the Baltic Sea
    Authors:
    Paweł Brzuzan, Hanna Mazur-Marzec, Maciej Florczyk, Filip Stefaniak, Anna Fidor, Robert Konkel, Maciej Woźny
    Academic press:
    Toxicology in Vitro (rok: 2020, tom: 68, strony: 104951), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tiv.2020.104951 - link to the publication
  4. Bioactive Peptides Produced by Cyanobacteria of the Genus Nostoc: A Review
    Authors:
    Anna Fidor, Robert Konkel, Hanna Mazur-Marzec
    Academic press:
    Marine Drugs (rok: 2019, tom: 17, strony: 561), Wydawca: MDPI Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/md17100561 - link to the publication
  5. Comparative characterization of two cyanobacteria strains of the order Spirulinales isolated from the Baltic Sea – phylophasic approach in practice
    Authors:
    Szubert, K.; Toruńska-Sitarz, A.; Słoń-Egiert, J.; Wiglusz, M.; Mazur-Marzec, H.
    Academic press:
    Algal Research (rok: 2021, tom: 55, strony: 102170), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.algal.2020.102170 - link to the publication

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