Projects funded by the NCN

Patient-specific iPS cells as a novel approach to study patophysiology of mTOR-related neurodevelopmental disorders

Call: SONATA 6 , Panel: NZ3

Principal investigator: dr Ewa Liszewska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

New mechanisms of cellular reprogramming: role of TLR3 and RIG-1 activation and downstream anti-inflammatory response to...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: dr Jacek Grzegorz Stępniewski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Studies of efficacy of microvesicles derived from genetically modified stem cells as carriers for proangiogenic and card...

Call: SONATA BIS 3 , Panel: NZ3

Principal investigator: dr hab. Ewa Katarzyna Zuba-Surma

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Inducible pluripotent stem cells as a tool in articular cartilage regeneration.

Call: SONATA BIS 2 , Panel: NZ3

Principal investigator: dr Wiktoria Maria Suchorska

Wielkopolskie Centrum Onkologii

Topology matters: rationally designed electron and hole transporting materials towards efficient and stable inverted per...

Call: OPUS 28 , Panel: ST5

Principal investigator: dr hab. Daniel Prochowicz

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Multi-omics and functional analyses towards type 2 diabetes: targeting altered pathways and metabolic rearrangements

Call: OPUS 27 , Panel: NZ4

Principal investigator: dr hab. Maciej Maurycy Łałowski

Uniwersytet im. Adama Mickiewicza w Poznaniu

Miniature CRISPR/Cas nucleases for upregulation of utrophin expression: a novel approach for mutation-independent therap...

Call: DAINA 3 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński

How inactivation of Mitochondrial Calcium Uniporter protects dopaminergic neurons

Call: OPUS 25 , Panel: NZ4

Principal investigator: prof. Jacek Marceli Kuźnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

It takes two to tango_ a decryption of Marfan cardiomyopathy using human iPSC- derived cardiac cells and engineered hear...

Call: OPUS 24 (LAP) , Panel: NZ3

Principal investigator: dr hab. Natalia Rozwadowska

Instytut Genetyki Człowieka PAN

Multiomic level analyses in atypical diabetes patient derived iPSC and pancreatic cells- key to function

Call: POLONEZ BIS 1 , Panel: NZ4

Principal investigator: dr hab. Maciej Maurycy Łałowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Identification of molecular mechanism underlying the phenotype development of Emery-Dreifuss muscular dystrophy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Katarzyna Piekarowicz

Uniwersytet Wrocławski, Wydział Biotechnologii

Presymptomatic synaptic disorders in Alzheimer's disease

Call: JPco-fuND2 Call 2021 , Panel: NZ5

Principal investigator: dr Michalina Maria Wężyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Development of an innovative method of preparing iPS cells for gene-cell therapy of hereditary diseases based on the Ost...

Call: PRELUDIUM 19 , Panel: NZ2

Principal investigator: dr Agnieszka Karolina Fus-Kujawa

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Novel insights into hydrogen sulfide-mediated cytoprotection - can H2S prevent the progression of Duchenne muscular dyst...

Call: OPUS 18 , Panel: NZ3

Principal investigator: prof. Agnieszka Łoboda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Functionalized peptide hydrogels as a tool to support skeletal muscle regeneration and therapeutic potential of myogenic...

Call: OPUS 18 , Panel: NZ5

Principal investigator: prof. Maria Anna Ciemerych-Litwinienko

Uniwersytet Warszawski, Wydział Biologii

Molecular and cellular mechanisms of pro-regenerative activity of stem cell- derived extracellular vesicles (EVs) in isc...

Call: MAESTRO 11 , Panel: NZ3

Principal investigator: prof. Ewa Katarzyna Zuba-Surma

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Analysis of intracellular mechanisms regulating transgene expression from AAV vectors of various serotypes

Call: PRELUDIUM 17 , Panel: NZ1

Principal investigator: Izabela Kraszewska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficienc...

Call: OPUS 16 , Panel: NZ3

Principal investigator: dr hab. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Significance of transcription factors associated with epithelial-mesenchymal transition and myogenesis in the developmen...

Call: OPUS 15 , Panel: NZ5

Principal investigator: prof. Marcin Marek Majka

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Impaired angiogenesis in Duchenne muscular dystrophy - is there a role for heme oxygenase-1 and statins?

Call: OPUS 11 , Panel: NZ1

Principal investigator: dr hab. Agnieszka Łoboda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Embryotoxicity and teratogenicity as a result of response to DNA damage in iPS cells: the effect of methylmercury chlori...

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: Justyna Augustyniak

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

MicroRNA profiling in cellular models of Huntington's disease generated using iPSC technology

Call: PRELUDIUM 9 , Panel: NZ2

Principal investigator: dr Emilia Barbara Kozłowska

Instytut Chemii Bioorganicznej PAN