Projects funded by the NCN

Selenium level and selenoprotein gene alterations as risk factors of cancers in Poland.

Call: PRELUDIUM 2 , Panel: NZ2

Principal investigator: dr Katarzyna Jaworska-Bieniek

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarsko-Biotechnologiczny i Medycyny Laboratoryjnej

Disorders of indispensable metals homeostasis and changes in levels of toxic metals in alternative materials in patients...

Call: PRELUDIUM 2 , Panel: NZ7

Principal investigator: dr Anna Woźniak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Design, synthesis and biological evaluation of methylthio analogues of combretastatin A-4 - potential antimitotic agents

Call: OPUS 2 , Panel: NZ7

Principal investigator: prof. Stanisław Sobiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Design, synthesis and biological evaluation of Steroid Sulfatase Inhibitors based on organophosphorus compounds.

Call: SONATA 2 , Panel: NZ7

Principal investigator: dr Sebastian Demkowicz

POLITECHNIKA GDAŃSKA

Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Predictive Potential of Circulating MicroRNA Biomarkers in Patients with High Familial or Genetic Risk of Cancer

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Wojciech Fendler

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marika Frańczak

Gdański Uniwersytet Medyczny, Wydział Lekarski

Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Ryszard Ostaszewski

Instytut Chemii Organicznej Polskiej Akademii Nauk

Are bisphenol S and F safe substitutes for bisphenol A in the face of environmental contamination with estrogenic mycoto...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marta Kozieł

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The effect of PKC epsilon modification on autophagy in cancer cells.

Call: OPUS 2 , Panel: NZ7

Principal investigator: prof. Maria Rybczyńska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego PZH - Państwowy Instytut Badawczy

Evaluation of anti-neoplastic activity of LAB-derived postbiotics as a potential tool to support standard chemotherapy i...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Janusz Szemraj

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Precise molecular characterization of circulating tumour cells in patients with triple negative breast cancer using high...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Stefano Volinia

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Urszula Piotrowska

Warszawski Uniwersytet Medyczny

Gaining control on XBP1s signaling as a starting point for novel cancer therapies

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Rafał Bartoszewski

Uniwersytet Wrocławski, Wydział Biotechnologii

High-throughput PET imaging by decoding multi-photon signals on long axial field-of-view PET using physics-guided artifi...

Call: OPUS 24 (LAP) , Panel: NZ7

Principal investigator: prof. Ewa Stępień

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

Call: OPUS 24 (LAP) , Panel: NZ7

Principal investigator: dr hab. Anna Więckowska

Uniwersytet Jagielloński, Collegium Medicum

A smart stride for cancer: synergistic effect of co-delivery chemo- andphototherapeutic agents using magneto-fluorescent...

Call: POLONEZ BIS 2 , Panel: NZ7

Principal investigator: dr Prachi Ghoderao

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Dawid Dorna

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Bionanoparticles with a molecular targeting device as a weapon for breast cancer

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Sylwia Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Sławomir Filipek

Uniwersytet Warszawski, Wydział Chemii

ECbiome genotyping and assessment of its involvement in pathogenic processes of endometrial cancer development

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Aleksandra Kowalczyk

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Polycyclic aromatic hydrocarbons as potential factors disrupting the functions of the ovary and promoting the developmen...

Call: SONATA 17 , Panel: NZ9

Principal investigator: dr Anna Kozubek

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

Electrospun nanofiber-based nanoplatform for delivery of new nutraceutical derivatives to eliminate chemotherapy-induced...

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Maciej Wnuk

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

Impact of the CDK4/6 targeted degradation by PROTACs on immune checkpoint signaling in cancer

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr Katarzyna Magiera-Mularz

Uniwersytet Jagielloński, Wydział Chemii

Structure-guided design of histone demethylase inhibitors for cancer therapy.

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Piotr Małecki

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Anna Florczak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Light-producing, oxygen-delivering, cancer cell-targeted carriers for photosensitisers dedicated for photodynamic therap...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Marek Murias

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Biomedical and chemometric assessment of the new analytical platform in the study of endogenous substances as potential ...

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr Lucyna Konieczna

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Mikołaj Czajkowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Anticancer activity of novel derivatives of 9,10-Anthraquinone Dithiocarbamates

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Natalia Maciejewska

Politechnika Gdańska

New synthetic resveratrol derivatives with potential anti-ageing and anti-cancer properties

Call: PRELUDIUM 2 , Panel: NZ7

Principal investigator: dr Justyna Mikuła-Pietrasik

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Olga Ciupak

Politechnika Gdańska, Wydział Chemiczny

Identification of breast cancer cells death and senescence mechanisms induction resulting from telomerase silencing with...

Call: OPUS 2 , Panel: NZ7

Principal investigator: dr hab. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Estrogenic mycotoxins (ZEA, α-ZOL) and tumor progression - an in vitro model of obesity and breast cancer

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Kinga Urbanek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Sylwia Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Synthetic epidermal growth factor receptor inhibitor conjugated with nobel metal nanoparticles as a potential drug for t...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Shaoshan Mai

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Weronika Kotkowiak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Anna Pogorzelska

Narodowy Instytut Leków

Nanoplastic and silver nanoparticles as a factor modulating the activity of estrogen-dependent intracellular signaling p...

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Grzelak

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Smart polymer delivery systems for photosensitizers to cancer cells

Call: PRELUDIUM BIS 2 , Panel: NZ7

Principal investigator: prof. Tomasz Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The impact of UPF1 ATP mimetics on the mutant immunopeptidome

Call: OPUS 20 , Panel: NZ7

Principal investigator: prof. Theodore Hupp

Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

Delivery of immuno-activators to phagocytic cells in order to obtain an anti-tumor response

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr Tomasz Rygiel

Warszawski Uniwersytet Medyczny

Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Tomasz Wróbel

Uniwersytet Medyczny w Lublinie

Drug repurposing to target p53 protein family for improved therapy in the relapsed TP53 and EGFR mutated lung cancer

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr Joanna Zawacka-Pankau

Warszawski Uniwersytet Medyczny

Comparison of the mechanism of action of valproic acid and levetiracetam as histone deacetylase inhibitors in ovarian ca...

Call: PRELUDIUM 2 , Panel: NZ7

Principal investigator: Patrycja Kwiecińska

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

Mechanisms of modification breast cancer risk by environmentally induced epigenetic changes.

Call: PRELUDIUM BIS 2 , Panel: NZ2

Principal investigator: dr hab. Tomasz Wojdacz

Pomorski Uniwersytet Medyczny w Szczecinie

Understanding the regulation of GDF11 signaling in the context of the gastrointestinal diseases

Call: PRELUDIUM BIS 2 , Panel: NZ7

Principal investigator: dr hab. Marta Zielińska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski