Projects funded by the NCN


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38 projects found matching your search criteria :

  1. New steroidal platinum complexes with potential application in medicine

    Call: OPUS 8 , Panel: ST5

    Principal investigator: prof. Rafał Ryszard Siciński

    Uniwersytet Warszawski, Wydział Chemii

  2. New and efficient methods for the flexible molecular docking of proteins.

    Call: MAESTRO 6 , Panel: ST6

    Principal investigator: prof. Andrzej Koliński

    Uniwersytet Warszawski, Wydział Chemii

  3. Structure and reactivity of avidin-like proteins

    Call: OPUS 5 , Panel: ST4

    Principal investigator: dr Jarosław Jan Panek

    Uniwersytet Wrocławski, Wydział Chemii

  4. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  5. Modifications of aglycones of leucomycins via Michael addition and Huisgen dipolar cycloaddition as a new routes of synt...

    Call: SONATA BIS 1 , Panel: ST5

    Principal investigator: dr hab. Piotr Przybylski

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  6. New bioinformatics method for predicting ligand-binding sites in RNA structures

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: dr Anna Philips

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  7. Development of a new scoring function for models of protein-small molecule complexes and its use for studying the mechan...

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: dr Irina Tuszyńska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  8. Identification of proteolytic cleavage sites in peptide substrates using coarse-grained docking and machine learning met...

    Call: OPUS 29 , Panel: NZ1

    Principal investigator: dr hab. Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  9. Design and Pharmacological Evaluation of Marine Alkaloid-Inspired 5-HT2A Receptor Ligands

    Call: PRELUDIUM 24 , Panel: NZ1

    Principal investigator: Szymon Kazimierz Kordylewski

    Instytut Farmakologii PAN

  10. Theoretical prediction, chemical synthesis and biological analysis of a novel class of HSPA5 inhibitors

    Call: OPUS 25 , Panel: ST4

    Principal investigator: prof. Arkadiusz Chworoś

    Centrum Badań Molekularnych i Makromolekularnych PAN

  11. New bioactive planar chiral ansa-ferrocenes conjugates with natural compounds - synthesis, enantioseparation, in vitro b...

    Call: SONATINA 7 , Panel: ST5

    Principal investigator: dr Maria Katarzyna Mazur

    Sieć Badawcza ŁUKASIEWICZ - Instytut Chemii Przemysłowej imienia Profesora Ignacego Mościckiego

  12. Allosteric regulation of cathepsins and procathepsins enzymatic activity by glycosaminoglycans and their mimetics

    Call: SONATINA 7 , Panel: ST4

    Principal investigator: dr Krzysztof Kamil Bojarski

    Politechnika Gdańska, Wydział Chemiczny

  13. New insights into the docking interactions between thioflavin T and misfolded proteins

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: Viktoria Babenko

    Uniwersytet Warszawski, Wydział Chemii

  14. The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Maciej Spiegel

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

  15. Multi-scale method for amyloid fibril assembly using protofilament structures predicted by coarse-grained docking simula...

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  16. Stop the biting: tracking the insecticide-mediated allosteric changes in voltage-gated sodium channels and design of sel...

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: dr Beata Niklas

    Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

  17. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  18. Integrative methods for modeling protein-protein complexes and multimolecular assemblies

    Call: SHENG 2 , Panel: NZ2

    Principal investigator: dr hab. Sebastian Kmiecik

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  19. Self-learning systems in the design of compounds modulating GPCR receptors activation.

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Dorota Latek

    Uniwersytet Warszawski, Wydział Chemii

  20. Development of tools for the rational design of peptide therapeutics

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Sebastian Kmiecik

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  21. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Mikołaj Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  22. Towards automatic derivation of geometry-based descriptors as surrogates for complex structural approaches in enzyme-sub...

    Call: PRELUDIUM 19 , Panel: NZ2

    Principal investigator: Carlos Eduardo Sequeiros Borja

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  23. Combination of Molecular Simulation and Deep Learning for De Novo Drug Design

    Call: PRELUDIUM 19 , Panel: ST6

    Principal investigator: dr Tomasz Jakub Danel

    Uniwersytet Jagielloński, Wydział Matematyki i Informatyki

  24. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Adam Stasiulewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  25. Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell ...

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  26. The use of evolutionary patterns in the optimization of chemotherapy of tuberculosis

    Call: SONATA BIS 9 , Panel: NZ6

    Principal investigator: dr Alina Ewa Minias

    Instytut Biologii Medycznej PAN

  27. Development of a new protein-protein docking method based on the flexible docking of short peptide fragments.

    Call: OPUS 17 , Panel: NZ2

    Principal investigator: dr Mateusz Kurciński

    Uniwersytet Warszawski

  28. Computational insights into procathepsin maturation mediated by glycosaminoglycans.

    Call: PRELUDIUM 16 , Panel: ST4

    Principal investigator: Krzysztof Kamil Bojarski

    Uniwersytet Gdański, Wydział Chemii

  29. Modeling of glycosaminoglycan-induced formation of protein structure and enhancement of biologically relevant protein-li...

    Call: SONATA BIS 8 , Panel: ST4

    Principal investigator: dr Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  30. Combining Rosetta method with deeply coarse grained SURPASS model into a novel multiscale algorithm for modeling protein...

    Call: OPUS 15 , Panel: ST6

    Principal investigator: dr hab. Dominik Gront

    Uniwersytet Warszawski, Wydział Chemii

  31. Extension of the CABS-dock method for protein-peptide docking to modelling of membrane proteins

    Call: PRELUDIUM 15 , Panel: NZ1

    Principal investigator: Maciej Paweł Ciemny

    Uniwersytet Warszawski, Wydział Chemii

  32. Integrative modeling and structure determination of macromolecular complexes comprising RNA and proteins

    Call: MAESTRO 9 , Panel: NZ1

    Principal investigator: prof. Janusz Marek Bujnicki

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  33. Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Małgorzata Gobis

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  34. Inhibitors, protein aggregation and carbon nanotube

    Call: OPUS 1 , Panel: NZ1

    Principal investigator: dr hab. Mai Suan Li

    Instytut Fizyki PAN

  35. Computational approaches to study protein-glycosaminoglycan interactions

    Call: POLONEZ 2 , Panel: ST4

    Principal investigator: dr Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  36. Development of protocol for in silico design of compounds inhibit Ebola virus infection

    Call: PRELUDIUM 11 , Panel: NZ2

    Principal investigator: Dawid Zdzisław Warszycki

    Instytut Farmakologii PAN

  37. Global protein docking algorithms based on the UNRES coarse-grained model

    Call: PRELUDIUM 9 , Panel: ST4

    Principal investigator: dr Paweł Krupa

    Uniwersytet Gdański, Wydział Chemii

  38. Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the lig...

    Call: SONATA 1 , Panel: NZ2

    Principal investigator: dr Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN