Projects funded by the NCN


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315 projects found matching your search criteria :

  1. Mechanostability of proteins and their complexes

    Call: PRELUDIUM 1 , Panel: ST3

    Principal investigator: Mateusz Sikora

    Instytut Fizyki PAN

  2. Design and synthesis of acylpeptide hydrolase inhibitors as potential inducers of apoptosis in tumor cells

    Call: PRELUDIUM 5 , Panel: ST5

    Principal investigator: Maciej Walczak

    Politechnika Wrocławska, Wydział Chemiczny

  3. Structural analysis of substrate binding region of Hsp40 protein

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Maciej Baranowski

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  4. The role of the 5' non-coding regions of p53 mRNA transcripts, which are synthesized from various transcription promoter...

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: prof. Jerzy Ciesiołka

    Instytut Chemii Bioorganicznej PAN

  5. A novel continuous method of proteolysis in hierarchically structured microreactor

    Call: SONATA 5 , Panel: ST8

    Principal investigator: dr Katarzyna Szymańska

    Politechnika Śląska, Wydział Chemiczny

  6. Design and synthesis of selective and irreversible inhibitors of HAT protease.

    Call: PRELUDIUM 5 , Panel: ST5

    Principal investigator: Marcin Skoreński

    Politechnika Wrocławska, Wydział Chemiczny

  7. Determination of the structural elements responsible for the narrow substrate specificity of staphylococcal proteases Sp...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Michał Zdżalik

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  8. Unnatural amino acids as a tool for optimization of substrates architecture for targeting human cysteine protease, cathe...

    Call: PRELUDIUM 5 , Panel: ST5

    Principal investigator: dr Marcin Poręba

    Politechnika Wrocławska, Wydział Chemiczny

  9. Biochemical and physiological characterization of human protease HtrA3

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: prof. Barbara Lipińska

    Uniwersytet Gdański, Wydział Biologii

  10. Susceptibility of human antimicrobial peptides to the action of aspartic proteases secreted by pathogenic yeast Candida ...

    Call: PRELUDIUM 5 , Panel: NZ1

    Principal investigator: Oliwia Bocheńska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  11. Kinesin in motion relatively to tubulin - properties of solvation water and interactions between proteins

    Call: SONATA 5 , Panel: NZ1

    Principal investigator: dr Anna Kuffel

    Politechnika Gdańska, Wydział Chemiczny

  12. Virtual High Throughput Screening (vHTS) derivation of a cross-immunity model for the Influenza-A Virus Infections.

    Call: OPUS 5 , Panel: NZ2

    Principal investigator: dr hab. Dariusz Plewczyński

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  13. Extracellular proteolytic activity of human epithelium - role in the modulation of signal transduction.

    Call: SYMFONIA 1 , Panel: NZ1

    Principal investigator: prof. Jan Potempa

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  14. Molecular mechanisms of chaperones in protein disaggregation

    Call: MAESTRO 4 , Panel: NZ1

    Principal investigator: prof. Krzysztof Liberek

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  15. Designing mRNA transcripts resistant to enzymatic cap hydrolysis applicable for anti-cancer vaccines; multiplexed bioche...

    Call: MAESTRO 4 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii

  16. Synthesis and application of chiral bicyclic proline's derivatives for the synthesis of enantiodifferenting, traceless, ...

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: dr Katarzyna Kasperowicz-Frankowska

    Politechnika Łódzka, Wydział Chemiczny

  17. Influence of knotted structure on function of proteins and protein structure prediction

    Call: SONATA BIS 2 , Panel: NZ1

    Principal investigator: dr hab. Joanna Sułkowska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  18. Investigation of MCPIP1 transcript function using smRNA FISH. Role of MCPIP1 protein in the regulation of inflammation.

    Call: PRELUDIUM 4 , Panel: NZ1

    Principal investigator: Jakub Kochan

    Uniwersytet Jagielloński w Krakowie, Wydział Biochemii, Biofizyki i Biotechnologii

  19. Fluorescent substrates of neutrophil proteinases: design, chemical synthesis , selection by the combinatorial chemistry ...

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: dr Jadwiga Popow - Stellmaszyk

    Uniwersytet Gdański, Wydział Chemii

  20. Bioinformatic analysis of GmrSD, a Type IV Modification-Dependent Restriction Systems

    Call: PRELUDIUM 4 , Panel: NZ2

    Principal investigator: Magdalena Machnicka

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  21. Induction of functional and structural rearrangement of the photosynthetic apparatus in mesophyll and bundle sheath chlo...

    Call: OPUS 4 , Panel: NZ3

    Principal investigator: prof. Elżbieta Romanowska

    Uniwersytet Warszawski, Wydział Biologii

  22. Electrokinetic characteristics of interaction between recombinant HSA monolayers and ionic ligands

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: Marta Kujda

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  23. Halogen Bonding in Protein-Ligand Complexes. Thermodynamics and Structural Studies on Rationally Selected Protein-Ligand...

    Call: OPUS 4 , Panel: ST4

    Principal investigator: prof. Jarosław Poznański

    Instytut Biochemii i Biofizyki PAN

  24. Identification of the adhesins of pathogenic fungi Candida "non-albicans"

    Call: OPUS 4 , Panel: NZ1

    Principal investigator: prof. Andrzej Kozik

    UNIWERSYTET JAGIELLOŃSKI, Wydział Biochemii Biofizyki i Biotechnologii

  25. Exploration of new polyheterocyclic, chiral compounds containing pyrrolidine and imidazole rings in asymmetric synthesis...

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: Aneta Wróblewska

    Uniwersytet Łódzki, Wydział Chemii

  26. Proteins at solid interfaces and proteinic structures in simulations and experiment

    Call: OPUS 1 , Panel: ST3

    Principal investigator: prof. Marek Cieplak

    Instytut Fizyki PAN

  27. The impact of human HAX-1 protein expression and localisation on granulopoiesis.

    Call: PRELUDIUM 4 , Panel: NZ1

    Principal investigator: Alicja Trębińska

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  28. Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

    Call: SONATA 4 , Panel: NZ1

    Principal investigator: dr Dorota Latek

    Uniwersytet Warszawski, Wydział Chemii

  29. Protein tyrosine phosphatases inhibition as a strategy against infectious diseases and bioterrorism

    Call: PRELUDIUM 4 , Panel: NZ1

    Principal investigator: dr Alicja Kuban-Jankowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  30. Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary...

    Call: OPUS 4 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Wydział Fizyki

  31. Exploration of zinc proteome - Identification and characterization of new zinc domains and their function in stabilizati...

    Call: SONATA BIS 2 , Panel: NZ1

    Principal investigator: dr hab. Artur Krężel

    Uniwersytet Wrocławski, Wydział Biotechnologii

  32. Structure and properties of protein layers: from biomolecules to a functional layer (a combined experimental and simulat...

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Barbara Jachimska

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  33. Structure of Neisseria meningitidis serogroup B population in Poland, 2010-2014.

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Izabela Waśko

    Narodowy Instytut Leków

  34. Structure and dynamics of protein chain at its folding temparature

    Call: PRELUDIUM 3 , Panel: ST4

    Principal investigator: Anna Hałabis

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  35. UP9/LSU protein as a potential function modulator of selective autophagy receptor in plants

    Call: PRELUDIUM 3 , Panel: NZ1

    Principal investigator: Katarzyna Zientara-Rytter

    Instytut Biochemii i Biofizyki PAN

  36. Structural study of the complexes of hydrolytic enzymes with heteroorganic substrates and substrate analogs

    Call: OPUS 3 , Panel: ST4

    Principal investigator: dr hab. Jarosław Błaszczyk

    Centrum Badań Molekularnych i Makromolekularnych PAN

  37. Synthesis of protein fragments of pathogens mimics human proteins and their use in diagnosis and prognosis of rheumatoid...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: Inga Relich

    Politechnika Łódzka, Wydział Chemiczny

  38. Biological mechanism of resting state raft formation and their participation in the regulation of certain cellular funct...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: prof. Aleksander Sikorski

    Uniwersytet Wrocławski, Wydział Biotechnologii

  39. Analysis of interactions of Galleria mellonella anionic and cationic defense peptides, the representatives of four disti...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: dr hab. Małgorzata Cytryńska

    Uniwersytet Marii Curie-Skłodowskiej, Wydział Biologii i Biotechnologii

  40. Functional relationship among cucumber CsMTP5, CsMTP6 and CsMTP7: the three phylogenetically diffrent members of metal t...

    Call: SONATA 3 , Panel: NZ1

    Principal investigator: dr Magdalena Migocka

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  41. Synchrotron small angle X-ray scattering and TEM microscopy studies of Hsp90:Sgt1:Rar1 and Sgt1 TPR domain dimer complex...

    Call: PRELUDIUM 3 , Panel: ST3

    Principal investigator: Michał Taube

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  42. Beyond the translational cycle - pleiotropic role of ribosomal L12 protein

    Call: PRELUDIUM 3 , Panel: NZ1

    Principal investigator: dr Leszek Wawiórka

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  43. Mechanics of single molecules: REELIN - neuronal growth steering protein.

    Call: PRELUDIUM 3 , Panel: ST3

    Principal investigator: dr Karolina Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  44. Studies of the processes of aggregation of GAPDH and other proteins participating in neurodegenerative diseases, induced...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: prof. Grzegorz Bartosz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska, Katedra Biofizyki Molekularnej

  45. Regulation mechanism of mRNA surveillance NMD complex in Arabidopsis thaliana.

    Call: SONATA 3 , Panel: NZ1

    Principal investigator: dr Izabela Wawer

    Uniwersytet Warszawski, Wydział Biologii

  46. New beta-lactoglobulin variants with increased affinity to selected highly toxic drugs

    Call: OPUS 3 , Panel: ST5

    Principal investigator: prof. Krzysztof Lewiński

    Uniwersytet Jagielloński, Wydział Chemii

  47. New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an...

    Call: SONATA BIS 1 , Panel: ST5

    Principal investigator: dr hab. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  48. Multidomain and multimeric proteins: structural and mechanical insights

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: dr Bartosz Różycki

    Instytut Fizyki PAN

  49. The role of Maf1 protein, repressor of Pol III RNA, in controlling tRNA stabilization

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: dr Tomasz Turowski

    Politechnika Warszawska, Wydział Chemiczny

  50. Molecular characterization of Chd64 and FKBP39 proteins, key components of multiprotein complex mediating juvenile hormo...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: prof. Andrzej Ożyhar

    Politechnika Wrocławska, Wydział Chemiczny