Projects funded by the NCN

Dissecting mechanisms of RNA-based Stress Granules formation, their structure and role in the development of Multi-Drug ...

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

The structural consequences of lysenin oligomerization- a toxin specifically binding sphingomyelin in lipid rafts

Call: SONATA 8 , Panel: NZ1

Principal investigator: dr Magdalena Kulma

Instytut Biochemii i Biofizyki PAN

Structure-based dynamical models of large and complex biomolecular systems

Call: OPUS 8 , Panel: ST3

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

Identification and comprehensive classification of nucleases including human nucleases

Call: OPUS 8 , Panel: NZ1

Principal investigator: dr hab. Krzysztof Flawiusz Ginalski

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Structure-function studies of RNA-binding proteins with FAST motifs and a RAP domain.

Call: SONATA 8 , Panel: NZ1

Principal investigator: dr Maria Wiktoria Górna

Uniwersytet Warszawski, Wydział Chemii

Molecular basis of amyloidogenesis - structure of conformational dynamics slected complexes of human prion protein PrPc ...

Call: OPUS 8 , Panel: ST4

Principal investigator: prof. Maciej Leszek Kozak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

2-Oxoglutarate dependent oxygenases in the biosynthesis of pharmacologically active alkaloids - structure, catalytic mec...

Call: SONATA BIS 4 , Panel: NZ1

Principal investigator: prof. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Approach to structures of difficult protein targets using new mass spectrometry-based methods

Call: MAESTRO 6 , Panel: NZ1

Principal investigator: prof. Michał Lech Dadlez

Instytut Biochemii i Biofizyki PAN

New and efficient methods for the flexible molecular docking of proteins.

Call: MAESTRO 6 , Panel: ST6

Principal investigator: prof. Andrzej Koliński

Uniwersytet Warszawski, Wydział Chemii

Modeling realistic tear film structure including tear protein and analyzing its role in stability and biophysical proper...

Call: PRELUDIUM 6 , Panel: ST7

Principal investigator: Alicja Ewa Wizert

Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

Crystallographic investigation of mammalian serum albumins in complexes with ligands

Call: OPUS 6 , Panel: ST5

Principal investigator: dr Anna Danuta Bujacz

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

An integrated approach to the prediction of the structures of proteins and protein complexes with the use of the coarse-...

Call: HARMONIA 5 , Panel: ST4

Principal investigator: prof. Józef Adam Liwo

Uniwersytet Gdański, Wydział Chemii

Virtual High Throughput Screening (vHTS) derivation of a cross-immunity model for the Influenza-A Virus Infections.

Call: OPUS 5 , Panel: NZ2

Principal investigator: dr hab. Dariusz Michał Plewczyński

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Influence of knotted structure on function of proteins and protein structure prediction

Call: SONATA BIS 2 , Panel: NZ1

Principal investigator: dr hab. Joanna Sułkowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Halogen Bonding in Protein-Ligand Complexes. Thermodynamics and Structural Studies on Rationally Selected Protein-Ligand...

Call: OPUS 4 , Panel: ST4

Principal investigator: prof. Jarosław Poznański

Instytut Biochemii i Biofizyki PAN

Structure and properties of protein layers: from biomolecules to a functional layer (a combined experimental and simulat...

Call: OPUS 4 , Panel: ST5

Principal investigator: dr hab. Barbara Jachimska

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Structure of Neisseria meningitidis serogroup B population in Poland, 2010-2014.

Call: PRELUDIUM 4 , Panel: NZ7

Principal investigator: Izabela Joanna Waśko

Narodowy Instytut Leków

Structure and dynamics of protein chain at its folding temparature

Call: PRELUDIUM 3 , Panel: ST4

Principal investigator: Anna Maria Hałabis

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Structural study of the complexes of hydrolytic enzymes with heteroorganic substrates and substrate analogs

Call: OPUS 3 , Panel: ST4

Principal investigator: dr hab. Jarosław Błaszczyk

Centrum Badań Molekularnych i Makromolekularnych PAN

Synchrotron small angle X-ray scattering and TEM microscopy studies of Hsp90:Sgt1:Rar1 and Sgt1 TPR domain dimer complex...

Call: PRELUDIUM 3 , Panel: ST3

Principal investigator: Michał Taube

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

New beta-lactoglobulin variants with increased affinity to selected highly toxic drugs

Call: OPUS 3 , Panel: ST5

Principal investigator: prof. Krzysztof Lewiński

Uniwersytet Jagielloński, Wydział Chemii

Multidomain and multimeric proteins: structural and mechanical insights

Call: OPUS 3 , Panel: NZ1

Principal investigator: dr Bartosz Jan Różycki

Instytut Fizyki PAN

Solution NMR investigations of human cystatin C - structure, dynamics and protein-ligand interactions.

Call: PRELUDIUM 2 , Panel: ST4

Principal investigator: Martyna Ewa Maszota-Zieleniak

Uniwersytet Gdański, Wydział Chemii

Structure and function of acireductone dioxygenases - experimental and computational studies.

Call: OPUS 2 , Panel: NZ1

Principal investigator: dr hab. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

3D structure-based search for selective inhibitor of thymidylate synthase of nematodes, a potential drug in chemotherapy...

Call: OPUS 1 , Panel: NZ6

Principal investigator: prof. Wojciech Krzysztof Rode

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Physicochemical and structural study on the influence of charged amino acidic residues presence in the sequence in stabi...

Call: SONATA 1 , Panel: ST4

Principal investigator: dr Joanna Makowska

Uniwersytet Gdański, Wydział Chemii

Structure prediction of proteins and large protein assemblies guided by low-resolution or/and sparse experimental data.

Call: SONATA 1 , Panel: NZ2

Principal investigator: dr Dominik Gront

Uniwersytet Warszawski, Wydział Chemii

Influence of the disorder structure of the transcriptional factor Yin Yang 1 (YY1) on masking effect of the N-terminal a...

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Adam Kazimierz Górka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii