Projects funded by the NCN
Crystallographic investigation of mammalian serum albumins in complexes with ligands
2013/11/B/ST5/02271
Keywords:
crystal structure serum albumins protein - ligand interactions
Descriptors:
- ST5_16:
- ST5_20:
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 6 - announced on 2013-09-16
Amount awarded: 585 000 PLN
Project start date (Y-m-d): 2014-08-01
Project end date (Y-m-d): 2017-07-31
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Mikroskop stereoskopowy z kamerą i przystawką polaryzacyjną (45 000 PLN)
- Termomikser (17 000 PLN)
- Spektrofotometr - nanodrop (41 000 PLN)
- Komputer ze stacją graficzną (30 900 PLN)
Information in the final report
- Publication in academic press/journals (3)
- Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum Albumin.Authors:Sekula B., Bujacz A.*Academic press:Journal of Medicinal Chemistry (rok: 2016, tom: 59(1), strony: 82-89), Wydawca: ACS PublicationsStatus:PublishedDOI:10.1021/acs.jmedchem.5b00909 - link to the publication
- Crystal structures of serum albumins from domesticated ruminants and their complexes with 3,5-diiodosalicylic acid.Authors:Bujacz A, Talaj JA, Zielinski K, Pietrzyk-Brzezinska AJ, Neumann P.Academic press:Acta Crystallogr D Struct Biol. (rok: 2017, tom: 73, strony: 896-909), Wydawca: WileyStatus:PublishedDOI:10.1107/S205979831701470X - link to the publication
- Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic propertiesAuthors:Sekula B., Ciesielska A., Rytczak P., Koziolkiewicz M., Bujacz A.*Academic press:Bioscience Reports (rok: 2016, tom: -, strony: 1-13 e00338), Wydawca: Portland PressStatus:PublishedDOI:10.1042/BSR20160089 - link to the publication