Projects funded by the NCN


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59 projects found matching your search criteria :

  1. The role of neutrophil extracellular traps and mammalian target of rapamycin complex (mTORc) in the ethiopathogenesis of...

    Call: OPUS 9 , Panel: NZ6

    Principal investigator: prof. Jacek Musiał

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

  2. Changes in iron metabolism induced by anticancer compounds in in vitro and in vivo

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Jędrzej Antosiewicz

    Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

  3. Structure-function studies of RNA-binding proteins with FAST motifs and a RAP domain.

    Call: SONATA 8 , Panel: NZ1

    Principal investigator: dr Maria Górna

    Uniwersytet Warszawski, Wydział Chemii

  4. The functional meaning of the protein kinase C beta (PKC beta) translocation due to cerebral ischemia. Solving the puzzl...

    Call: SONATA 8 , Panel: NZ3

    Principal investigator: dr Małgorzata Beręsewicz

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  5. Role of protein kinase G type I alpha in the regulation of filtration barrier in glomerular dysfunction.

    Call: SONATA BIS 4 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  6. Enzymatic catalysis as a versatile tool for the synthesis of 1,3-dimethylxanthine derivatives with potential anticancer ...

    Call: PRELUDIUM 7 , Panel: ST5

    Principal investigator: dr Paweł Borowiecki

    Politechnika Warszawska, Politechnika Warszawska

  7. Understanding the mechanism of action for small molecule kinase inhibitors in alleviating myotonic dystrophy type 1 (DM1...

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej PAN

  8. Regulation of photosynthesis and growth of Arabidopsis thaliana under salt stress.

    Call: SONATA 7 , Panel: NZ3

    Principal investigator: dr Anna Kulik

    Instytut Biochemii i Biofizyki PAN

  9. Proteomic analysis of changes in brain and liver mitochondria in apoE-knockout mice – influence of metformin – an AMP-ac...

    Call: PRELUDIUM 1 , Panel: NZ2

    Principal investigator: dr Maciej Suski

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

  10. Hydration effects in protein kinases

    Call: SONATA 6 , Panel: ST4

    Principal investigator: dr Piotr Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  11. Study of function of ZmCPK11 and its closest homologues from Arabidopsis thaliana in abiotic stresses

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: dr Jadwiga Szczegielniak

    Instytut Biochemii i Biofizyki PAN

  12. Jasmonic acid biosynthesis enviromental regulation through mitogen-activated protein kinases in Arabidopsis thaliana.

    Call: SONATA 1 , Panel: NZ3

    Principal investigator: dr Łukasz Gałgański

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  13. Investigation of the mechanisms of stress induced changes in synaptic plasticity in the dentate gyrus of mice.

    Call: SONATA 5 , Panel: NZ4

    Principal investigator: dr Jadwiga Spyrka

    Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

  14. Assembly analysis of MAPKKK18 protein complexes: characterisation of MAPKKK18-dependent ABA signalling pathway

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Agnieszka Ludwików

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  15. Modification of glomerular filtration barrier permeability by the insulin, oxidative stress and protein kinase G type I ...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  16. Contribution of calcium-dependent protein kinases (CDPKs) to signalling pathways of abiotic and biotic stresses in potat...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Lidia Polkowska-Kowalczyk

    Instytut Biochemii i Biofizyki PAN

  17. Mechanisms underlaying the signaling function of PKC beta I and beta II in mitochondria after cerebral ischemia

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: prof. Barbara Zabłocka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  18. The role of the FAM69 protein family in the nervous system.Analysis of a novel family with potential protein kinase func...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr hab. Krzysztof Pawłowski

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Rolnictwa i Biologii

  19. The role of sirtuins and AMPK protein kinase in insulin resistance of podocytes

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr Dorota Rogacka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  20. An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Arkadiusz Orzechowski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  21. The role of SnRK2 kinases in plant response to environmental stresses. The interplay between SnRK2 kinases, PP2C phospha...

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: prof. Grażyna Dobrowolska

    Instytut Biochemii i Biofizyki PAN

  22. Investigation of histidine phosphorylation in thymidylate synthase and searching for causative protein kinase

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: dr hab. Joanna Cieśla

    POLITECHNIKA WARSZAWSKA

  23. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

    Call: SONATA 19 , Panel: NZ1

    Principal investigator: dr Anna Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  24. Deciphering the importance of the intracellular FGFR1 module for cell fate

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr hab. Małgorzata Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  25. Regulacja procesu deoksyhypuzynacji przez kinazy białkowe

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Paweł Kochanowski

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  26. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  27. The potassium puzzle: unraveling the connection between the potassium channel and lipid kinases in kidney functioning

    Call: OPUS 25 , Panel: NZ1

    Principal investigator: dr hab. Piotr Koprowski

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  28. The effect of PKC epsilon modification on autophagy in cancer cells.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Maria Rybczyńska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  29. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  30. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

    Call: OPUS 24 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  31. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Sławomir Kasperowicz

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  32. Unraveling mechanisms and physiological outcome of lipid-evoked regulation of proteostasis in the intestine.

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: dr hab. Grzegorz Sumara

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  33. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  34. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Ireneusz Majsterek

    Uniwersytet Medyczny w Łodzi

  35. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  36. Cell-based high-throughput screening for small-molecule compounds diminishing molecular markers of pathogenesis in myoto...

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  37. FAST interactions in cell death regulation

    Call: PRELUDIUM 19 , Panel: NZ1

    Principal investigator: Daria Dawidziak

    Uniwersytet Warszawski, Wydział Chemii

  38. Role of heteromultimerization of MRCK kinases in physiological and pathological processes.

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Brygida Baran

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  39. Restoration of beta-cell function via inhibition of diabetic kinome.

    Call: SONATA BIS 9 , Panel: NZ1

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński

  40. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  41. Evaluation of endoplasmic reticulum stress control by endogenous lipids in the context of its anticancer therapeutic pot...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr Dariusz Pytel

    Uniwersytet Medyczny w Łodzi, Międzywydziałowa Katedra Chemii i Biochemii Medycznej

  42. Functional and biochemical characterization of Arabidopsis calcium sensor SCS

    Call: OPUS 1 , Panel: NZ3

    Principal investigator: dr Maria Bucholc

    Instytut Biochemii i Biofizyki PAN

  43. DEVELOPMENT OF NEW CLASS PHOTOACTIVATED ANTICANCER-ANTIFUNGAL COMPOUNDS: CONJUGATES OF GOLD NANOPARTICLE-SUPPORTED QUINO...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Oleh Demchuk

    Sieć Badawcza ŁUKASIEWICZ - Instytut Farmaceutyczny

  44. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Paweł Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  45. Evaluation of the impact of exercise / stress stimuli on the mechanisms and efficacy of beta-hydroxy-beta-methylbutyric ...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr hab. Krzysztof Durkalec-Michalski

    Akademia Wychowania Fizycznego im. Eugeniusza Piaseckiego w Poznaniu

  46. Structure and function of a unique two-component system of periodontopathogenic bacteria Porphyromonas gingivalis

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: prof. Jan Potempa

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  47. Role of the lysosomes in insulin-dependent regulation of AMP-ativated protein kinase expression and activity in podocyte...

    Call: PRELUDIUM 15 , Panel: NZ4

    Principal investigator: Patrycja Rachubik

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  48. Integrating light and osmotic stress signaling- molecular functions of Plastid Movement Impaired 1 protein from Arabidop...

    Call: OPUS 15 , Panel: NZ3

    Principal investigator: dr Olga Sztatelman

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  49. The impact of reversible Arp4 phosphorylation on chromatin remodeling

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: prof. Jan Sadowski

    Uniwersytet im. Adama Mickiewicza, Wydział Biologii

  50. SnRK2 protein kinases as integrators of environmental signals in the regulation of the senescence in plants

    Call: OPUS 14 , Panel: NZ3

    Principal investigator: dr Anna Kulik

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk