Projects funded by the NCN

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846 projects found matching your search criteria :

  1. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Kucińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  2. Make an old drug great again – isoniazid/rifamycin-boron clusters conjugates – synthesis and antitubercular activity....

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Bogusława Olejniczak

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  3. Polymersomes specifically releasing cGAMP and doxorubicin in tumor hypoxic regions as a new anti-cancer therapeutic stra...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: dr hab. Ryszard Smolarczyk

    Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Oddział w Gliwicach

  4. Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme

    Call: PRELUDIUM BIS 2 , Panel: NZ5

    Principal investigator: dr hab. Anna Dominika Mrozek-Wilczkiewicz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  5. Regulation of a plant based synergistic toxicity between triterpene saponins and ribosome-inactivating proteins

    Call: OPUS 20 (LAP) , Panel: NZ7

    Principal investigator: prof. Adam Matkowski

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  6. Smart polymer delivery systems for photosensitizers to cancer cells

    Call: PRELUDIUM BIS 2 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Gośliński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  7. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  8. Does tormentil tincture (Tormentillae tinctura) support the therapy of leaky gut syndrome?

    Call: SONATINA 5 , Panel: NZ7

    Principal investigator: dr Aleksandra Karolina Kruk

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  9. Benchmarking Human Tissue Culture Systems that Mimic the Tumor Microenvironment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Matthias Nees

    Uniwersytet Medyczny w Lublinie

  10. Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Weronika Paulina Kotkowiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  11. The impact and mechanism of action of the lactoperoxidase system modified by using non-physiological substrates on cario...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Marcin Rafał Magacz

    Uniwersytet Jagielloński, Collegium Medicum

  12. Interplay between neuroplasticity and CC/CXC chemokine inflamatory pathways in depression.

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  13. Bioabsorbable hydroxyapatite/polymer nanocomposite granules with enhanced osteoconductivity and anti-inflammatory proper...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: dr Vladyslav Vivcharenko

    Uniwersytet Medyczny w Lublinie

  14. Novel combination therapies of pulmonary arterial hypertension targeting blockade of peripheral cannabinoid CB1 receptor...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Barbara Malinowska

    Uniwersytet Medyczny w Białymstoku

  15. Dual 5-HT3 receptor/5-HT6 receptor antagonists in neuropsychiatric and neurological disorders

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Paweł Maria Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  16. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  17. Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

    Call: OPUS 22 , Panel: HS6

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Agnieszka Magdalena Woźniak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  19. Effects of activation of cholinergic, noradrenergic, and serotonergic systems on respiratory impairment in Alzheimer's d...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kaczyńska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  20. Understanding drug/polymer/plasticizer miscibility and its effect on mechanical properties of polymeric filaments for FD...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Marta Maria Kozakiewicz-Latała

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  21. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  22. Evaluation of butterbur (Petasites spp) for the antimigraine potential: Isolation of bioactive secondary metabolites (pe...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Łukasz Dawid Kulinowski

    Uniwersytet Medyczny w Lublinie

  23. The assessment of purity and identity confirmation of extracellular vesicles withcapillary electrophoresis

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Aleksandra Steć

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  24. Searching for natural bioactive farnesoid X receptor agonists and their role in parenteral nutrition-associated liver di...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Maciej Jan Stawny

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  25. The advanced novel materials for effective bleeding and antimicrobial control in TCCC (Tactical Combat Casualty Care) an...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Dorota Chełminiak-Dudkiewicz

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

  26. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Piotrowska

    Warszawski Uniwersytet Medyczny

  27. Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Bernadeta Pietrzak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  28. Heart Failure-Induced Alterations in Platelet Phenotype: Impact on Lung Microvascular Endothelial Barrier Integrity.

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Mohammadebrahim Hosseinzadehmaleki

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  29. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  30. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  31. Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. Metabolomic comparison of Mycobacterium tuberculosis and Mycobacterium marinum model organisms in response to antimicrob...

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Marcin Ziomek

    Uniwersytet Medyczny w Lublinie

  33. Electrospinning as an effective approach to topical delivery of natural compounds with wound healing potential

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Anna Gościniak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  34. Controlling the covalent activity of a PD-L1 inhibitors with light

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Wiktor Uzar

    Uniwersytet Jagielloński w Krakowie

  35. The novel analytical technique of evaluation and imaging of the progress of selected chemical reactions assisted by MW/U...

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Alina Cherniienko

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  36. A Compound Screening Platform for the Discovery of Histone- and Nucleosome-Targeting Agents

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Curtis Davey

    Uniwersytet Jagielloński w Krakowie

  37. The role of gut microbiota in the treatment of epilepsy: experimental studies

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: prof. Piotr Wlaź

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie

  38. The development of the new safe and controlled anticoagulant therapy with the use of cationically-modified polymers in t...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Andrzej Mogielnicki

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  39. The role of GPR39 receptor in the mechanism of antidepressant action

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Katarzyna Młyniec

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  40. Targeted drug delivery systems - synthesis and functionalization of nanocarriers

    Call: SONATA 2 , Panel: ST5

    Principal investigator: dr Krzysztof Szczepanowicz

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  41. Preparation and investigation of the biologically active systems with potential anticancer activity, containing P,N-; N,...

    Call: SONATA 2 , Panel: NZ7

    Principal investigator: dr Monika Richert

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  42. The optimal rate of cooling and protection against brain hyperferremia - as a potential therapy of neonatal asphyxia

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Justyna Rogalska

    Uniwersytet Mikołaja Kopernika, Wydział Biologii i Ochrony Środowiska

  43. Analysis of the use of medicines containing psychotropic substances of the IV-P group, emphasis on anxiolytic and hypnot...

    Call: SONATA 2 , Panel: NZ7

    Principal investigator: dr Anna Gołda

    Uniwersytet Jagielloński-Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  44. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  45. Bioconjugates labeled with alpha- and beta-particle emitting radionuclides as potential radiopharmaceuticals in Targeted...

    Call: SONATA BIS 9 , Panel: ST4

    Principal investigator: dr hab. Marek Pruszyński

    Instytut Chemii i Techniki Jądrowej

  46. Endocannabinoid regulation of the motivational tone at the mesolimbic system driven by inflammation

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. Novel bispecific G-quadruplex conjugates as potential anticancer agents

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: dr Carolina Sofia Pereira Roxo

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  48. Synthetic analogues of opioid growth factor linked to derivatives of glucosamine as a potential compounds for targeted t...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Iwona Maria Inkielewicz-Stępniak

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  49. The influence of EGFRvIII structure and its cellular distribution heterogeneity on designing new therapeutic and diagnos...

    Call: OPUS 18 , Panel: NZ3

    Principal investigator: prof. Piotr Rieske

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  50. In vivo effects, underlying signaling pathways and mechanism of action of ghrelin receptor agonist against pathological ...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Piotr Chmielarz

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

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