Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The impact and mechanism of action of the lactoperoxidase system modified by using non-physiological substrates on cariogenic biofilms

2021/41/N/NZ7/03315

Keywords:

lactoperoxidase system biofilm dental caries Streptococcus mutans glycolysis glucosyltransferase B

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_12: Prevention of human diseases
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marcin Rafał Magacz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 20 - announced on 2021-03-15

Amount awarded: 209 990 PLN

Project start date (Y-m-d): 2022-01-26

Project end date (Y-m-d): 2025-01-25

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Safety Assessment of the Modified Lactoperoxidase System—In Vitro Studies on Human Gingival Fibroblasts
    Authors:
    Marcin Magacz, Monika Papież, Dorota Kościelniak, Anna Jurczak, Karolina Kędziora, Elżbieta Pamuła, Wirginia Krzyściak
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24(3), strony: 2640), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms24032640 - link to the publication
  2. Safety Assessment of the Modified Lactoperoxidase System—In Vitro Studies on Human Gingival Fibroblasts
    Authors:
    Marcin Magacz, Monika Papież, Dorota Kościelniak, Anna Jurczak, Karolina Kędziora, Elżbieta Pamuła, Wirginia Krzyściak
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24(3), strony: 2640), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms24032640 - link to the publication
  3. Modified Lactoperoxidase System as a Promising Anticaries Agent: In Vitro Studies on Streptococcus mutans Biofilms
    Authors:
    Marcin Magacz, Sergio Alatorre-Santamaría, Karolina Kędziora, Kacper Klasa, Paweł Mamica,Wiktoria Pepasińska, Magdalena Lebiecka, Dorota Kościelniak, Elżbieta Pamuła, Wirginia Krzyściak
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24(15), strony: 12136), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms241512136 - link to the publication