Projects funded by the NCN

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82 projects found matching your search criteria :

  1. Structural studies of the impact of gemini surfactants on model amyloidogenic peptides.

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Julia Ludwiczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  2. Do copper(I) complexes with conjugates of phosphine-peptide carriers can cause selective cancer cells death? Synthesis, ...

    Call: SONATA 12 , Panel: ST5

    Principal investigator: dr Urszula Komarnicka

    Uniwersytet Wrocławski, Wydział Chemii

  3. Inhibitors of BTLA-HVEM complex formation as potential targets for cancer immunotheraphy

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Marta Spodzieja

    Uniwersytet Gdański, Wydział Chemii

  4. Searching for mu opioid receptor peptide agonists with G protein/beta-arrestin biased profile and their pharmacological ...

    Call: SONATA 14 , Panel: ST5

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  5. De novo designed, structurally extended peptide foldamers and their use for construction of PD-1/PD-L1 interaction inhib...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Łukasz Berlicki

    Politechnika Wrocławska

  6. Innovative hybrid materials useful in the syntheis of dressings for the treatment of diabetic foot ulcers

    Call: OPUS 16 , Panel: ST8

    Principal investigator: dr hab. Beata Kolesińska

    Politechnika Łódzka, Wydział Chemiczny

  7. Structure-activity relationship of bifunctional peptides, agonists of opioid receptors and antagonists of neurokinin rec...

    Call: PRELUDIUM 2 , Panel: ST5

    Principal investigator: Jolanta Dyniewicz

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  8. Identification of amino acid residues located in positions P7 and P8 of model inhibitor of proprotein convertases that d...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: Izabela Małuch

    Uniwersytet Gdański, Wydział Chemii

  9. Synthetic peptides - study on physochemical properties and biological activity

    Call: OPUS 3 , Panel: ST5

    Principal investigator: dr Wojciech Mrozik

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  10. Characterization of CD44/p53 signaling involved in the CD44-dependent cancer stem cells: small molecules and peptides, t...

    Call: MAESTRO 3 , Panel: ST5

    Principal investigator: prof. Tadeusz Holak

    Uniwersytet Jagielloński, Wydział Chemii

  11. Alpha factor of S. cerevisiae yeast: formation of copper and zinc complexes and their biological activity

    Call: OPUS 5 , Panel: ST5

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  12. A development of a method of micro-scale synthesis of peptides labelled with stable isotopes for quantitative proteomics

    Call: PRELUDIUM 6 , Panel: ST4

    Principal investigator: Maciej Modzel

    Uniwersytet Wrocławski, Wydział Chemii

  13. Determination of the exact structure of the complex (complexes) of AB1-16 peptide with Pd(II) ions using nuclear magneti...

    Call: PRELUDIUM 7 , Panel: ST5

    Principal investigator: Mariusz Mital

    Instytut Biochemii i Biofizyki PAN

  14. Engineering disulfide bridges in human beta-defensin 3 for novel antibacterial and antifungal activities

    Call: SONATA 8 , Panel: ST5

    Principal investigator: dr Aleksandra Walewska

    Uniwersytet Gdański, Wydział Chemii

  15. Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple recept...

    Call: OPUS 9 , Panel: ST5

    Principal investigator: prof. Anna Janecka

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  16. Study on cyclic peptides conversion caused by the transfer of acyl group from nitrogen atom onto sulfur atom

    Call: OPUS 10 , Panel: ST5

    Principal investigator: dr hab. Piotr Stefanowicz

    Uniwersytet Wrocławski, Wydział Chemii

  17. MOLECULAR INSIGHTS INTO BIOSYNTHESIS OF PEPTIDE AZOLE ANTIBIOTICS

    Call: SONATA 15 , Panel: NZ1

    Principal investigator: dr Dmitry Gilyarov

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  18. Application of N-(2-thioethyl)glycine analogues in orthogonal cleavage of peptides from solid support

    Call: PRELUDIUM 18 , Panel: ST4

    Principal investigator: Magdalena Elżbieta Wierzbicka

    Uniwersytet Wrocławski, Wydział Chemii

  19. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  20. The design and development of the peptide inhibitors library targeting Zn(II)-binding site of matrix metalloproteinases ...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Paulina Alicja Potok

    Uniwersytet Wrocławski, Wydział Chemii

  21. Novel receptor materials for the construction of a bioelectronic nose for the rapid and efficient detection of lung canc...

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  22. Frog skin derived cyclic peptide as a molecular scaffold to create a novel tool for combining visualization and inhibiti...

    Call: PRELUDIUM 23 , Panel: ST5

    Principal investigator: Aleksandra Helbik-Maciejewska

    Uniwersytet Gdański

  23. Synthesis and evaluation of PD-L1 inhibitors based on mixed mode scaffolds containing amino acid derivatives, short pept...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Ewa Maria Surmiak

    Uniwersytet Jagielloński, Wydział Chemii

  24. Supramolecular Peptide Organic Frameworks (POFs)

    Call: SYMFONIA 4 , Panel: ST5

    Principal investigator: prof. Agnieszka Szumna

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  25. Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Piotr Maciej Chyży

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  26. Retro-inverso modification of zinc(II)–GLP-1 receptor agonist complexes – from bioinorganic chemistry to animal studies...

    Call: OPUS 26 , Panel: ST5

    Principal investigator: dr hab. Magdalena Rowińska-Żyrek

    Uniwersytet Wrocławski, Wydział Chemii

  27. Oligopeptide Scaffolds for pi-Extended Switchable Chromophores

    Call: OPUS 12 , Panel: ST5

    Principal investigator: dr hab. Miłosz Pawlicki

    Uniwersytet Wrocławski, Wydział Chemii

  28. Peptide conjugates as the novel antimicrobial compounds for eradication of intracellular infections and biofilm.

    Call: SONATA 12 , Panel: ST5

    Principal investigator: dr Paulina Kosikowska-Adamus

    Uniwersytet Gdański, Wydział Chemii

  29. Peptide foldamer-based nanostructures

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Monika Szefczyk

    Politechnika Wrocławska

  30. Understanding the interactions of zinc with metal-sensing transcriptional regulators from Mycobacterial ArsR-family

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Sławomir Potocki

    Uniwersytet Wrocławski, Wydział Chemii

  31. New class of nucelus penetrating peptides. Design, synthesis and mechanism of action

    Call: OPUS 14 , Panel: ST5

    Principal investigator: dr hab. Magdalena Wysocka

    Uniwersytet Gdański, Wydział Chemii

  32. Synthesis of new functional cages based on trigonal peptidic building blocks by dynamic covalnt chemistry

    Call: PRELUDIUM 15 , Panel: ST5

    Principal investigator: Marcin Grajda

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  33. A novel strategy for construction of antifungal pro-drugs based on the cell-penetrating peptides

    Call: OPUS 3 , Panel: ST5

    Principal investigator: prof. Sławomir Milewski

    Politechnika Gdańska, Wydział Chemiczny

  34. Helical peptides rich in aminoisobutyric acid residues - synthesis, electrical properties and interactions with model li...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: dr Joanna Juhaniewicz

    Uniwersytet Warszawski, Wydział Chemii

  35. Oxidative modification of amino acid residues in proteins - synthetic studies towards selective detection

    Call: SONATA 4 , Panel: ST5

    Principal investigator: dr Monika Kijewska

    Uniwersytet Wrocławski, Wydział Chemii

  36. Quaternary ammonium salts of cryptando-peptidic conjugates. Synthesis and chemical properties.

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: dr Remigiusz Bąchor

    Uniwersytet Wrocławski, Wydział Chemii

  37. Synthetic cysteine peptides as molecular layers for studies of interactions between copper ions and beta-amyloid

    Call: SONATA 4 , Panel: ST4

    Principal investigator: dr Urszula Wawrzyniak

    Politechnika Warszawska, Wydział Chemiczny

  38. Synthesis and fragmentation of peptides conjugated with betaine derivatives - a search for isobaric markers for quantita...

    Call: OPUS 5 , Panel: ST4

    Principal investigator: prof. Zbigniew Szewczuk

    Uniwersytet Wrocławski, Wydział Chemii

  39. Synthesis, physico-chemical and biological studies on macromolecular carriers of antimicrobial peptides

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Urszula Piotrowska

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  40. Abeta 4-x peptides as copper binding molecules resistant to chelating drugs, promoting the formation of amyloid oligomer...

    Call: OPUS 8 , Panel: ST5

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki PAN

  41. Foldameric miniproteins - structure and catalytic function

    Call: OPUS 11 , Panel: ST5

    Principal investigator: dr hab. Łukasz Berlicki

    Politechnika Wrocławska

  42. The research on the use of novel analogues of endogenous antimicrobial peptides in therapy of staphylococcal skin infect...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  43. Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Izabela Siekierska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  44. Peptide-based luminescent coordination capsules and cages – towards bio-inspired cavities illuminated by chiral light

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Agnieszka Szumna

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  45. Studies on the metal ions impact on the structure and functions of peptidic inhibitors of aggregation of proteins involv...

    Call: OPUS 1 , Panel: ST5

    Principal investigator: dr Marek Łuczkowski

    Uniwersytet Wrocławski, Wydział Chemii

  46. The usage of synthetic peptides mimicking flap region of bacterial ureases for estimation of anti-urease diversity in rh...

    Call: SONATA 2 , Panel: NZ6

    Principal investigator: dr Iwona Konieczna

    Uniwersytet Jana Kochanowskiego w Kielcach, Wydział Matematyczno-Przyrodniczy

  47. The impact of synthetic modifications of the histidine side chain on coordination properties of analogues of the N-termi...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: dr Izabela Zawisza

    Instytut Biochemii i Biofizyki PAN

  48. Synthesis and biological studies of conjugates formed by peptide dendrimers and natural polyphenols and their analogs

    Call: OPUS 4 , Panel: ST5

    Principal investigator: prof. Zofia Lipkowska

    Instytut Chemii Organicznej PAN

  49. The self-assembly of superstructures of peptidic nanofibrils controlled by conformational memory effect

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Wojciech Dzwolak

    Instytut Wysokich Ciśnień Polskiej Akademii Nauk

  50. Spectroscopic exploration of conformationally variable metal-bound peptide monolayers: towards novel versatile optical n...

    Call: OPUS 15 , Panel: ST4

    Principal investigator: dr Agata Królikowska

    Uniwersytet Warszawski, Wydział Chemii

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