Projects funded by the NCN

New nucleotide analogs containing triazole within oligophosphate bridge as mimics of the 5' end of mRNA - synthesis, pro...

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: Sylwia Ciechanowicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Chemical syntesis and evaluation of biochemical properties of 7-methyloguanosine 5'-diphosphate analogs as inhibitors of...

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: Marcin Ziemniak

Uniwersytet Warszawski, Wydział Fizyki

THE EFFECT OF NUCLEOSIDE ANALOGUES ON REPLICATION OF CYHV-3 (CYPRINID HERPESVIRUS 3) IN CELL LINES OF COMMON CARP (CYPRI...

Call: PRELUDIUM 7 , Panel: NZ6

Principal investigator: Agnieszka Troszok

Polska Akademia Nauk Zakład Ichtiobiologii i Gospodarki Rybackiej w Gołyszu

Studies on the synthesis of newly discovered cyclic N6-threonylcarbamoyladenosine (ct6A) and its analogues and on the in...

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: Michał Matuszewski

Politechnika Łódzka, Wydział Chemiczny

Cellular and molecular mechanism of action of PPI dendrimer complexes with nucleoside analogue anticancer drugs

Call: OPUS 7 , Panel: NZ3

Principal investigator: prof. Barbara Klajnert-Maculewicz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

New gamma-lactam analogues of homo-N-nucleosides

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Joanna Gotkowska

Uniwersytet Medyczny w Łodzi, Katedra Chemii Bioorganicznej i Biokoordynacyjnej

Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

Call: OPUS 6 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

New 3,8-disubstituted purine nucleoside analogues as prospective application for research of structure and biological ac...

Call: SONATA 3 , Panel: ST5

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Pirymidine phosphorothioate analogues of nucleotides as multifunctional regulators of P2Y6 and P2Y14 nucleotide receptor...

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: Edyta Węgłowska

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Functional analyses of single nucleotide polymorphisms, rs10814948/9p24.2 and rs6702619/1p21.1, associating with colorec...

Call: PRELUDIUM 3 , Panel: NZ2

Principal investigator: Natalia Maryan

Centrum Medyczne Kształcenia Podyplomowego

Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

Call: SONATA 1 , Panel: ST5

Principal investigator: dr Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl...

Call: OPUS 2 , Panel: ST5

Principal investigator: dr hab. Piotr Guga

Centrum Badań Molekularnych i Makromolekularnych PAN

Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular bi...

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Dagmara Baraniak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

A new gereration of anticancer pronucleotides

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Jacek Stawiński

Instytut Chemii Bioorganicznej PAN

Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new struc...

Call: PRELUDIUM 16 , Panel: ST5

Principal investigator: dr Justyna Gołębiewska

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

The role of extracellular ATP fraction in induction of epithelial-mesenchymal transition - studies using analogs of nucl...

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Róża Pawłowska

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

Synthesis of trimethyl cap analogs modified with molecular rotors and their application in nuclear transport studies

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Błażej Wojtczak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Development of HTS method based on fluorescently labelled guanosine analogues: novel route for RNA (guanosine-N7)-methyl...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Renata Kasprzyk

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Application of LCMS to quantitative analysis of composition of in vitro transcribed RNAs containing chemically modified ...

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Dominika Strzelecka

Uniwersytet Warszawski, Wydział Fizyki

N-Oxide phosphobetaines in new synthetic strategies for P-modified phosphates and polyphospates of natural biomolecules ...

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Magdalena Materna

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Chemically modified mRNA for studies on cellular processes and therapeutic applications

Call: OPUS 11 , Panel: ST5

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Pro-nucleotides based on mRNA cap structure - synthesis, biological and biophysical evaluation

Call: SONATA 11 , Panel: ST5

Principal investigator: dr Karolina Piecyk

Uniwersytet Warszawski, Wydział Chemii

Aryl nucleoside phosphoroamidates - a new generation of anti-HIV pronucleotides.

Call: OPUS 1 , Panel: ST5

Principal investigator: prof. Jacek Stawiński

Instytut Chemii Bioorganicznej PAN

Synthesis and evaluation of a novel toolkit for biology and biotechnology based on adenine nucleotides analogs

Call: SONATA BIS 5 , Panel: ST5

Principal investigator: dr hab. Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Antiviral activity of novel acyclic phosphonate nucleoside analogues containing the 1,2,3-triazole moiety

Call: SONATA 1 , Panel: NZ4

Principal investigator: dr Iwona Głowacka

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny