Projects funded by the NCN

Development and characterization of novel multitargeted organometallic tubulin polymerization inhibitors for enhancing t...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Damian Nestor Plażuk

Uniwersytet Łódzki

Molecular mechanisms underlying the liver injury induced by ulipristal acetate treatment

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Aleksandra Natalia Łupińska

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Stimuli-Responsive Metal-Organic Frameworks: Structural Dynamics and Sorption Properties

Call: SONATINA 8 , Panel: ST5

Principal investigator: dr Marzena Pander

Uniwersytet Jagielloński

Manufacture of a new generation three-dimensional "drug-on-chip" materials with controlled release of active agents dedi...

Call: SONATINA 8 , Panel: ST8

Principal investigator: dr Wiktoria Dominika Tomal

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Stimuli-responsive anion transporters for targeted drug delivery

Call: OPUS 26 , Panel: ST5

Principal investigator: dr hab. Michał Jan Chmielewski

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Agnieszka Wnuk

Instytut Farmakologii PAN

Taming aggregation with AmyloGraph 2.0: a database and prediction models of amyloid self-assembly modulators

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Michał Jan Burdukiewicz

Uniwersytet Medyczny w Białymstoku

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Synthesis, characterization, and evaluation of the biological activity of innovative thermosensitive suppositories compr...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Ewa Olędzka

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

New biomimetic 3D materials for potential use in advanced therapies of bone tissue diseases - 3D BioBone

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Joanna Krystyna Kolmas

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Organometallic (Fe, Ru, Ir, Os) phospho-inducers of drug-resistant cancer cells' ferroptosis

Call: OPUS 26 , Panel: ST4

Principal investigator: dr hab. Urszula Katarzyna Komarnicka

Uniwersytet Wrocławski, Wydział Chemii

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Mucoadhesive nanospheres as an intravesical form of monomethyl auristatin E

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Jelonek

Centrum Materiałów Polimerowych i Węglowych PAN

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Application of superparamagnetic iron oxide nanoparticles (SPION) in inhaled theranostic systems containing antifungal d...

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Gabriela Małgorzata Wyszogrodzka-Gaweł

Uniwersytet Jagielloński, Collegium Medicum

Design and characterisation of sealing materials of prosthetic obturator being additionally a cytostatic drug reservoir....

Call: OPUS 26 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska

Evaluating the antibacterial activity of the bacteriophage protein targeting Staphylococcus aureus, including drug-resis...

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Zuzanna Maria Kaźmierczak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Controlled release of active pharmaceutical ingredients (API) based on Carrier-Ion-API interactions

Call: SONATA 19 , Panel: ST5

Principal investigator: dr Mariusz Piotr Sandomierski

Politechnika Poznańska, Wydział Technologii Chemicznej

Unlocking the potential of ion-transfer voltammetry based electronic tongues for date-rape drug detection in real sample...

Call: SONATA BIS 13 , Panel: ST4

Principal investigator: dr Emilia Katarzyna Witkowska-Nery

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Call: SONATA BIS 13 , Panel: NZ7

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Carbon quantum dots in the synthesis of functional polymeric materials using photoinduced atom transfer radical polymeri...

Call: PRELUDIUM BIS 5 , Panel: ST5

Principal investigator: prof. Paweł Artur Chmielarz

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

Click chemistry in microfluidic channels for the construction of nanomaterials against drug-resistant microbes.

Call: PRELUDIUM BIS 5 , Panel: ST11

Principal investigator: dr hab. Marek Brzeziński

Centrum Badań Molekularnych i Makromolekularnych PAN

Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Extracellular vesicles of probiotic yeast as carriers of biologically active molecules transferred to human intestinal c...

Call: OPUS 25 , Panel: NZ9

Principal investigator: dr hab. Jolanta Mierzejewska

Politechnika Warszawska, Wydział Chemiczny

Curdlan-based biomaterial as a nanostructure carrier for controlled and targeted drug delivery in the treatment of deep ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: dr Aleksandra Nurzyńska

Uniwersytet Medyczny w Lublinie

Development of bioresorbable polymer materials for the personalized ureteralstents releasing the antispasmodic drug

Call: OPUS 25 , Panel: ST11

Principal investigator: prof. Janusz Edward Kasperczyk

Centrum Materiałów Polimerowych i Węglowych PAN

Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr hab. Mariusz Łukasz Hartman

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Electromagnetic field-supported systems for transdermal drug delivery.

Call: OPUS 25 , Panel: ST8

Principal investigator: prof. Rafał Mariusz Rakoczy

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie, Wydział Technologii i Inżynierii Chemicznej

Multifunctional emulsion-based transporters for personalised cancer treatment

Call: OPUS 25 , Panel: ST8

Principal investigator: prof. Ewa Dłuska

Politechnika Warszawska, Wydział Inżynierii Chemicznej i Procesowej

Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

INVADOPODIA IN AXL-DRIVEN CANCER INVASION AND DRUG RESISTANCE

Call: OPUS 25 , Panel: NZ3

Principal investigator: dr Daria Paulina Zdżalik-Bielecka

Uniwersytet Warszawski, Wydział Biologii

"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Ryszard Józef Ostaszewski

Instytut Chemii Organicznej Polska Akademia Nauk

Bis(benzosiloxaboroles) as a new class of potential antibiotics - a perspective solution to growing problem of antimicro...

Call: PRELUDIUM 22 , Panel: ST5

Principal investigator: Krzysztof Nowicki

Politechnika Warszawska, Wydział Chemiczny

Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

Call: PRELUDIUM 22 , Panel: NZ1

Principal investigator: Piotr Maciej Chyży

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Alex Jun Matsuda

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Decrypting the "sulfation code" of glycosaminoglycans for understanding their function in the extracellular matrix

Call: OPUS 25 , Panel: ST4

Principal investigator: dr hab. Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

Call: PRELUDIUM 22 , Panel: ST5

Principal investigator: Izabela Siekierska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Modeling of the excipients effect on drug skin permeability

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Laura Agnieszka Krumpholz

Uniwersytet Jagielloński, Collegium Medicum

Chemosensors with molecularly imprinted polymers for determination of antiviral active drug substances in body fluids - ...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr Krzysztof Robert Noworyta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Design, Synthesis and Characterization of Functionalized 1,2,4-Trioxanes/Trioxepanes for Antimalarial and Anticancer Use

Call: SONATINA 7 , Panel: NZ7

Principal investigator: dr Mohit Kumar Tiwari

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Targeting nucleic acid-protein complexes with small molecules using a deep-learning framework

Call: SONATINA 7 , Panel: NZ1

Principal investigator: dr Ryhor Nikalayeu

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Senolytic nanoplatform to target and eliminate skin cancer Zombie cells

Call: M-ERA.NET 2022 , Panel: ST5

Principal investigator: dr hab. Anna Karolina Lewińska

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

Targeted inhibition of hypusination pathway

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr Przemysław Marek Grudnik

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Adam Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Urszula Helena Piotrowska

Warszawski Uniwersytet Medyczny

Antibiotic discovery by induction of inactive antibiotic gene clusters

Call: OPUS 24 , Panel: NZ1

Principal investigator: dr Bernhard Kepplinger

Uniwersytet Wrocławski, Wydział Biotechnologii

Plant bacterial endophytes as an important antibiotic-resistance dissemination vector

Call: SONATA 18 , Panel: NZ9

Principal investigator: dr Magdalena Marta Zalewska

Uniwersytet Warszawski, Wydział Biologii

Exploring the unknown drug-like chemical space: new classes of sulfoximine derivatives and their biological activities.

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Maciej Filip Dawidowski

Warszawski Uniwersytet Medyczny

Three-phase drug carriers - design towards a prolonged release, development of a transport model and its verification. C...

Call: PRELUDIUM BIS 4 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska