Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Modeling of the excipients effect on drug skin permeability

2023/49/N/NZ7/01039

Keywords:

pharmacokinetic modeling skin swine excipients

Descriptors:

  • NZ7_14:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Laura Agnieszka Krumpholz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 22 - announced on 2023-03-16

Amount awarded: 209 960 PLN

Project start date (Y-m-d): 2024-01-16

Project end date (Y-m-d): 2027-01-15

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Towards the understanding of the IVPT results variability-Development, verification and validation of the PBPK model of caffeine in vitro human skin permeation
    Authors:
    Krumpholz Laura, Polak Sebastian, Wiśniowska Barbara
    Academic press:
    European Journal of Pharmaceutical Sciences (rok: 2025, tom: 204, strony: nie dotyczy), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejps.2024.106943 - link to the publication
  2. Physiologically-based pharmacokinetic model of in vitro porcine ear skin permeation for drug delivery research
    Authors:
    Krumpholz Laura, Polak Sebastian, Wiśniowska Barbara
    Academic press:
    Journal of Applied Toxicology (rok: 2024, tom: 44, strony: 1936-1948), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jat.4687 - link to the publication