Projects funded by the NCN

Proteins at solid interfaces and proteinic structures in simulations and experiment

Call: OPUS 1 , Panel: ST3

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

The impact of human HAX-1 protein expression and localisation on granulopoiesis.

Call: PRELUDIUM 4 , Panel: NZ1

Principal investigator: Alicja Trębińska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Theoretical model of SH2-dependent STAT1 dimerization as a novel tool to identify specific compounds of functional inhib...

Call: PRELUDIUM 4 , Panel: NZ2

Principal investigator: Małgorzata Szeląg

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Structures of Actin-bound WH2 Domains of Spire: the Implication for Filament Nucleation

Call: OPUS 1 , Panel: NZ1

Principal investigator: prof. Tadeusz Holak

UNIWERSYTET JAGIELLOŃSKI, Wydzial Chemii UJ

Personalized medicine for CLL

Call: OPUS 1 , Panel: NZ4

Principal investigator: dr Małgorzata Rogalińska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Oxidative modification of amino acid residues in proteins - synthetic studies towards selective detection

Call: SONATA 4 , Panel: ST5

Principal investigator: dr Monika Kijewska

Uniwersytet Wrocławski, Wydział Chemii

Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

Call: SONATA 4 , Panel: NZ1

Principal investigator: dr Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Spatiotemporal dynamics of Rho GTPase activity during electrotaxis of cells representing different strategy of cell migr...

Call: OPUS 4 , Panel: NZ3

Principal investigator: prof. Zbigniew Madeja

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Examination of the thiazine reaction products of N-homocysteinylated proteins and their metabolites with aldehydes

Call: OPUS 4 , Panel: ST5

Principal investigator: dr hab. Rafał Głowacki

Uniwersytet Łódzki, Wydział Chemii

The impact of O-GlcNAc transferase on Polycomb dependent repression of genes associated with differentiation of breast c...

Call: OPUS 4 , Panel: NZ3

Principal investigator: dr hab. Anna Krześlak

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

DNA double-stranded break repair proteins as a target for personalized cancer therapy based on synthetic lethality

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr hab. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Members of eIF4E protein family, their affinities towards 5' mRNA cap and protein binding partners: an interdisciplinary...

Call: OPUS 4 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Wydział Fizyki

The role of AS160 protein in the myocytes fatty acid transport and subsequent development of insulin resistance

Call: PRELUDIUM 4 , Panel: NZ3

Principal investigator: Agnieszka Mikłosz

Uniwersytet Medyczny w Białymstoku

Identification of natural compounds activating PPAR (peroxisome-proliferator-activated receptors) - regulators of glucos...

Call: OPUS 1 , Panel: NZ9

Principal investigator: prof. Maria Koziołkiewicz

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Assessment of protective immunity against fasciolosis through vaccination of sheep with a multivalent stage-specific rec...

Call: HARMONIA 3 , Panel: NZ6

Principal investigator: dr Luke Norbury

Instytut Parazytologii im. Witolda Stefańskiego PAN

A unified coarse-grained model of biological macromolecules based on mean-field multipole-multipole interactions

Call: MAESTRO 3 , Panel: ST4

Principal investigator: prof. Józef Liwo

Uniwersytet Gdański, Wydział Chemii

The NUPDB project - The study of mutations in natively unfolded (stretches) of proteins related to human health and dise...

Call: HARMONIA 3 , Panel: NZ2

Principal investigator: dr hab. Lucjan Wyrwicz

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Molecular mechanisms behind functional diversification of mitochondrial Hsp70 chaperones

Call: MAESTRO 3 , Panel: NZ1

Principal investigator: prof. Jarosław Marszałek

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Structure and dynamics of protein chain at its folding temparature

Call: PRELUDIUM 3 , Panel: ST4

Principal investigator: Anna Hałabis

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Theoretical simulation of NMR parameters of heavy metals as a tool for structural research

Call: OPUS 1 , Panel: ST4

Principal investigator: dr hab. Magdalena Pecul-Kudelska

Uniwersytet Warszawski, Wydział Chemii

Synthesis of protein fragments of pathogens mimics human proteins and their use in diagnosis and prognosis of rheumatoid...

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: Inga Relich

Politechnika Łódzka, Wydział Chemiczny

Identifcation of regulatory effects of bacteriophages with therapeutic potential on mammalian cell functions and immunit...

Call: SONATA BIS 1 , Panel: NZ6

Principal investigator: dr hab. Krystyna Dąbrowska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

Biological mechanism of resting state raft formation and their participation in the regulation of certain cellular funct...

Call: OPUS 3 , Panel: NZ1

Principal investigator: prof. Aleksander Sikorski

Uniwersytet Wrocławski, Wydział Biotechnologii

Does overexpression of cell adhesion molecule L1 in rats with complete spinal cord transection influences the expression...

Call: PRELUDIUM 3 , Panel: NZ4

Principal investigator: dr Rafał Płatek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Finding a role of LAT adaptor in development of T cell acute lymphoblastic leukemia (T-ALL)

Call: OPUS 3 , Panel: NZ5

Principal investigator: dr hab. Arkadiusz Miążek

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

Call: OPUS 3 , Panel: NZ4

Principal investigator: dr Joanna Solich

Instytut Farmakologii PAN

Late neuroanatomical and neuropsychological sequelae of central nervous system prophylaxis in children with acute lympho...

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: dr Olga Zając-Spychała

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

The role of astrocytes and cellular metabolism in functional compensation of degeneration of dopaminergic system in the ...

Call: OPUS 3 , Panel: NZ4

Principal investigator: dr Katarzyna Kuter

Instytut Farmakologii, Polska Akademia Nauk

Functional relationship among cucumber CsMTP5, CsMTP6 and CsMTP7: the three phylogenetically diffrent members of metal t...

Call: SONATA 3 , Panel: NZ1

Principal investigator: dr Magdalena Migocka

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Analysis of the participation of TL1A protein and its receptor, DR3, in the pathomechanism of inflammatory bowel disease...

Call: OPUS 1 , Panel: NZ5

Principal investigator: prof. Zbigniew Kmieć

Gdański Uniwersytet Medyczny, Wydział Lekarski

Synchrotron small angle X-ray scattering and TEM microscopy studies of Hsp90:Sgt1:Rar1 and Sgt1 TPR domain dimer complex...

Call: PRELUDIUM 3 , Panel: ST3

Principal investigator: Michał Taube

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Picture of molecular interactions in systems of molecules with anesthetic properties - from an isolated monomer to compl...

Call: OPUS 3 , Panel: ST4

Principal investigator: prof. Maria Rospenk

Uniwersytet Wrocławski, Wydział Chemii

Beyond the translational cycle - pleiotropic role of ribosomal L12 protein

Call: PRELUDIUM 3 , Panel: NZ1

Principal investigator: dr Leszek Wawiórka

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

Mechanics of single molecules: REELIN - neuronal growth steering protein.

Call: PRELUDIUM 3 , Panel: ST3

Principal investigator: dr Karolina Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Evaluation of the cytokine profile of endothelial progenitor cells during the process of their differentiation

Call: PRELUDIUM 3 , Panel: NZ3

Principal investigator: Aneta Kantor

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

Role of reactive oxygen species in BCR/ABL+ cells resistance to IM

Call: PRELUDIUM 3 , Panel: NZ3

Principal investigator: Sylwester Głowacki

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Genetic and immunological analysis of PD-1 in patients with rheumatoid arthritis

Call: PRELUDIUM 1 , Panel: NZ5

Principal investigator: Anna Król

Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

The role of AnxA2-S100A10 complex in the initiation of mineralization by human osteoblast-like cells

Call: PRELUDIUM 3 , Panel: NZ3

Principal investigator: Anna Ćmoch

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Attempt to identify a molecular basis (mutation) of a new hereditary hemolytic anemia associated with the lack of MPP1 p...

Call: OPUS 3 , Panel: NZ5

Principal investigator: dr Dżamila Bogusławska

Uniwersytet Zielonogórski, Wydział Nauk Biologicznych

The role of PML protein and PML nuclear bodies in adult mouse brain

Call: SONATA BIS 1 , Panel: NZ4

Principal investigator: prof. Grzegorz Wilczyński

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Interaction of myosin VI and DOCK7; possible involvement in neuritogenesis

Call: OPUS 3 , Panel: NZ3

Principal investigator: prof. Maria Rędowicz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The influence of S100A6 on epidermal growth and differentiation

Call: PRELUDIUM 3 , Panel: NZ3

Principal investigator: Agnieszka Graczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Helicobacter pylori Dsb (disulfide bond) proteins - analysis of the relations between sequence, structure and function o...

Call: OPUS 3 , Panel: NZ1

Principal investigator: prof. Elżbieta Jagusztyn-Krynicka

Uniwersytet Warszawski, Wydział Biologii

Haplotypes and serum protein level of Brain-Derived Neurotrophic Factor (BDNF) analysis and their association with cogni...

Call: OPUS 1 , Panel: HS6

Principal investigator: prof. Aleksander Araszkiewicz

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera, Wydział Lekarski

Structure and properties of multicomponent lipid films and their interactions with pore-forming peptides.

Call: OPUS 3 , Panel: ST4

Principal investigator: dr hab. Sławomir Sęk

Uniwersytet Warszawski, Wydział Chemii

Bone tissue engineering with human mesenchymal stem cells, bone morphogenetic proteins, bioactive scaffolds and dynamic ...

Call: OPUS 1 , Panel: NZ4

Principal investigator: dr hab. Anna Osyczka

UNIWERSYTET JAGIELLOŃSKI

New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an...

Call: SONATA BIS 1 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Multidomain and multimeric proteins: structural and mechanical insights

Call: OPUS 3 , Panel: NZ1

Principal investigator: dr Bartosz Różycki

Instytut Fizyki PAN

New benzo[b]furane and dicarboximide derivatives with anticancer activity- studies on the mechanism of action in human c...

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: Karolina Królewska

Centrum Badań Molekularnych i Makromolekularnych PAN

The role of Maf1 protein, repressor of Pol III RNA, in controlling tRNA stabilization

Call: PRELUDIUM 1 , Panel: NZ1

Principal investigator: dr Tomasz Turowski

Politechnika Warszawska, Wydział Chemiczny