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Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Structures of Actin-bound WH2 Domains of Spire: the Implication for Filament Nucleation

2011/01/B/NZ1/00031

Keywords:

actin filament cytoskeleton Spire nucleation structure

Descriptors:

  • NZ1_4: Structural biology
  • NZ1_3: Biophysics
  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

UNIWERSYTET JAGIELLOŃSKI, Wydzial Chemii UJ

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Tadeusz Holak 

Number of co-investigators in the project: 2

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 706 620 PLN

Project start date (Y-m-d): 2011-12-06

Project end date (Y-m-d): 2015-10-05

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Naczynie Dewara.
  2. Modularna Chłodnia (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Side-binding proteins modulate actin filament dynamics
    Authors:
    Crevenna, A.H., Arciniega, M., Dupont, A., Mizuno, N., Kowalska, K., Lange, O.F., Wedlich-Söldner, R., Lamb, D.C.
    Academic press:
    eLife (rok: 2015, tom: 4, strony: e04599), Wydawca: eLife
    Status:
    Published
    DOI:
    10.7554/eLife.04599 - link to the publication
  2. Ablation of cyclase-associated protein 2 (CAP2) leads to cardiomyopathy
    Authors:
    Peche, V.S., Holak, T.A., Burgute, B.D., Kosmas, K., Kale, S.P., Wunderlich, F.T., Elhamine, F., Stehle, R., Pfitzer, G., Nohroudi, K., Addicks, K., Stockigt, F., Schrickel, J.W., Gallinger, J., Schleicher, M., Noegel, A.A.
    Academic press:
    Cell. Mol. Life Sci. (rok: 2013, tom: 70,, strony: 527-543), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-012-1142-y - link to the publication
  3. Molecular architecture of the Spire–actin nucleus and its implication for actin filament assembly
    Authors:
    Tomasz Sitar, Julia Gallinger, Anna M. Ducka, Teemu P. Ikonen, Michael Wohlhoefler, Kurt M. Schmoller, Andreas R. Bausch, Peteranne Joele, Kathleen M. Trybus, Angelika A. Noegel, Michael Schleicher, Robert Huber and Tad A. Holak
    Academic press:
    Proc. Natl. Acad. Sci. USA (rok: 2011, tom: 108, strony: 19575-19580), Wydawca: Natl. Acad. Sciences USA
    Status:
    Published
    DOI:
    10.1073/pnas.1115465108 - link to the publication

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