Projects funded by the NCN

Structures of oligomers of amyloid beta peptides: Multiscale molecular simulations.

Call: PRELUDIUM 14 , Panel: NZ1

Principal investigator: Dinh Quoc Huy Pham

Instytut Fizyki Polskiej Akademii Nauk

Mechanisms of binding and transport in plasma of amyloid beta oligomers by human serum albumin (HSA) in presence of sele...

Call: OPUS 14 , Panel: ST4

Principal investigator: prof. Maciej Kozak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

On the role of gangliosides, insulin and zinc ions in amylin interactions with biomimetic membranes

Call: SONATA 13 , Panel: ST4

Principal investigator: dr Joanna Juhaniewicz-Dębińska

Uniwersytet Warszawski, Wydział Chemii

Influence of hydration water properties on the process of amyloid fibrils formation

Call: SONATA 13 , Panel: NZ1

Principal investigator: dr hab. Piotr Bruździak

Politechnika Gdańska, Wydział Chemiczny

The self-assembly of superstructures of peptidic nanofibrils controlled by conformational memory effect

Call: OPUS 13 , Panel: ST5

Principal investigator: prof. Wojciech Dzwolak

Instytut Wysokich Ciśnień Polskiej Akademii Nauk

Interaction of membrane-active peptides with model cell membrane and their role in a drug delivery system. Electrochemic...

Call: OPUS 12 , Panel: ST4

Principal investigator: dr Piotr Pięta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Structural studies of the impact of gemini surfactants on model amyloidogenic peptides.

Call: PRELUDIUM 12 , Panel: ST5

Principal investigator: Julia Ludwiczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Mechanism of substrate recognition and binding by gamma-secretase on the example of the amyloid precursor protein

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Łukasz Nierzwicki

Politechnika Gdańska, Wydział Chemiczny

Study of mechanism of proteolysis and a selective ligand binding to gamma-secretase complex

Call: OPUS 12 , Panel: NZ2

Principal investigator: prof. Sławomir Filipek

Uniwersytet Warszawski, Wydział Chemii

Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube...

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Bożena Dziadek

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Is interaction with albumin is relevant for metal dependent toxicity of beta-amyloid peptides?

Call: PRELUDIUM 11 , Panel: NZ1

Principal investigator: Ewelina Stefaniak

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Synthesis and biological evaluation of novel, drug-like multifunctional ligands, as potential anti-Alzheimer's agents ta...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Dawid Panek

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Inhibitors, protein aggregation and carbon nanotube

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr hab. Mai Li

INSTYTUT FIZYKI PAN

Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Barbara Malawska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Copper induced Ab aggregation upon synaptic excitation. Reaction - diffusion simulations in realistic 3D reconstruction ...

Call: PRELUDIUM 10 , Panel: NZ1

Principal investigator: Wojciech Goch

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Interactions of amyloid beta peptides with metal ions and lipid membranes: Insights from lattice and all-atom simulation...

Call: OPUS 10 , Panel: ST4

Principal investigator: prof. Mai Li

Instytut Fizyki Polskiej Akademii Nauk

Self-aggregation of protein complexes: virus capsids and amyloids

Call: POLONEZ 1 , Panel: ST3

Principal investigator: dr Panagiotis Theodorakis

Instytut Fizyki Polskiej Akademii Nauk

New hydrids of tetrahydroacridine derivatives as a acetylocholinesterase with multifunctional activity

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Paweł Szymański

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

Conformational transition pathways and molecular mechanisms of aggregation of the amyloidogenic H-fragment of insulin

Call: OPUS 9 , Panel: NZ1

Principal investigator: prof. Wojciech Dzwolak

Uniwersytet Warszawski, Wydział Chemii

Physicochemical and structural aspects of fibrillogenesis modulated by halogeno-chalcone molecules in the presence of li...

Call: OPUS 9 , Panel: ST4

Principal investigator: dr Katarzyna Cieślik-Boczula

Uniwersytet Wrocławski, Wydział Chemii

Influence of neurotoxic factors on aspartate N-acetyltransferase activity in cholinergic neurons

Call: PRELUDIUM 9 , Panel: NZ3

Principal investigator: dr Marlena Zyśk

Gdański Uniwersytet Medyczny, Wydział Lekarski