Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of ceramide and sphingosine-1-phosphate receptor signalling in amyloid beta precursor protein metabolism.

2013/11/N/NZ4/02233

Keywords:

sphingolipids neurodegeneration neuroprotection

Descriptors:

  • NZ4_9: Systems neurobiology
  • NZ7_12: Prevention of human diseases

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Kinga Czubowicz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 98 640 PLN

Project start date (Y-m-d): 2014-07-24

Project end date (Y-m-d): 2018-05-23

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. komputer (3 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. The role of ceramide and SEW 2871 on transcription of enzymes involved in amyloid beta precursor protein metabolism in experimental model of Alzheimer's disease.
    Authors:
    Kinga Czubowicz, Sylwia Wójtowicz, Przemysław L. Wencel, Robert P. Strosznajder
    Academic press:
    Folia Neuropathologica (rok: 2018, tom: 56 numer 3, strony: 196-205), Wydawca: Polish Association of Neuropathologists and M. Mossakowski Medical Research Centre of the Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.5114/fn.2018.78700 - link to the publication
  2. The Role of Ceramide and Sphingosine-1-Phosphate in Alzheimer's Disease and Other Neurodegenerative Disorders
    Authors:
    Kinga Czubowicz, Henryk Jęśko, Przemysław Wencel, Walter Lukiw, Robert P. Strosznajder
    Academic press:
    Molecular Neurobiology (rok: 2019, tom: 56(8), strony: 5436-5455), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-018-1448-3 - link to the publication
  1. "Ceramide and sphingosine-1-phosphate crucial modulators of neuronal death. Relevance to neurodegenerative disorders". Prezentacja ustna, abstrakt.
    Authors:
    Kinga Czubowicz, Przemysław L. Wencel, Robert P. Strosznajder
    Conference:
    Advances in molecular and epigenetic mechanisms in neurodegeneration and neuroinflammation: novel therapeutic approaches". Neurochemical Conference (rok: 2017, ), Wydawca: Folia Neuropathologica
    Data:
    konferencja 19-20 październik
    Status:
    Published
  2. "The role of bioactive sphingolipid signalling in neuronal cell survival/death". Sesja posterowa. abstrakt
    Authors:
    Kinga Czubowicz, Przemysław L. Wencel, Robert P. Strosznajder
    Conference:
    Advances in molecular and epigenetic mechanisms in neurodegeneration and neuroinflammation: novel therapeutic approaches". Neurochemical Conference (rok: 2017, ), Wydawca: Folia Neuropathologica
    Data:
    konferencja 19-20 październik
    Status:
    Published

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