Projects funded by the NCN

Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

Call: OPUS 24 (LAP) , Panel: NZ7

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński, Collegium Medicum

Bunyaviral strategies to reorganize and exploit cellular translation

Call: SONATA BIS 12 , Panel: NZ1

Principal investigator: dr Piotr Gerlach

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Kamil Przyborowski

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Subsistence strategies and their transformations in the Late and Final Neolithic of East-Central Europe (SubTrans)

Call: OPUS 22 , Panel: HS3

Principal investigator: dr Łukasz Pospieszny

Uniwersytet Gdański, Wydział Historyczny

Why cells become smaller to survive? Analysis of tobacco BY2 cells adapted to osmotic and salt stress in the search of k...

Call: OPUS 20 , Panel: NZ9

Principal investigator: dr Agnieszka Szuba

Instytut Dendrologii PAN

Astrocytes-regulated oligomerization state of fructose bisphosphatase 2 (FBP2) in neurons as a basic factor regulating m...

Call: OPUS 19 , Panel: NZ4

Principal investigator: prof. Dariusz Stanisław Rakus

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

New regioselective chemical and biochemical strategies for proteins labeling

Call: OPUS 17 , Panel: ST4

Principal investigator: prof. Artur Krężel

Uniwersytet Wrocławski, Wydział Biotechnologii

The effect of nitric oxide on histone protein acetylation status in Phytophthora infestans (Mont.) de Bary

Call: OPUS 16 , Panel: NZ9

Principal investigator: dr hab. Magdalena Arasimowicz-Jelonek

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The effect of thiol redox regulators on seed quality and the aging process

Call: OPUS 16 , Panel: NZ9

Principal investigator: dr hab. Ewelina Antonina Ratajczak

Instytut Dendrologii PAN

Role of RNase activity of MCPIP1 protein in neuroblastoma suppression.

Call: PRELUDIUM 13 , Panel: NZ1

Principal investigator: dr Iwona Daria Nowak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Structural determinants of optical control of insulin and neuroligin release by photoactive protein ligands.

Call: OPUS 12 , Panel: ST4

Principal investigator: prof. Wiesław Nowak

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

The role of the ESCRT-0 protein complex in viral RNA-dependent activation of TLR3 signaling in murine astrocytes

Call: PRELUDIUM 12 , Panel: NZ6

Principal investigator: Matylda Barbara Mielcarska

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Medycyny Weterynaryjnej

ADAM17 as a key protein in cellular response to proinflammatory mediators

Call: OPUS 11 , Panel: NZ3

Principal investigator: prof. Joanna Katarzyna Bereta

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The influence of air pollution on the metabolic activity, chemical composition and proteins profile of silver birch (Bet...

Call: PRELUDIUM 11 , Panel: NZ8

Principal investigator: Monika Anna Ziemianin

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Memetic algorithms for the excited ligand diffusion in condensed biological matter

Call: PRELUDIUM 10 , Panel: ST3

Principal investigator: Jakub Mateusz Rydzewski

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Recognition of genes associated with H3K4me3 histone protein responsible for polarization of neutrophils into suppressor...

Call: OPUS 9 , Panel: NZ6

Principal investigator: dr hab. Przemysław Andrzej Lewkowicz

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The role of HAX-1 protein in induction of pro-inflammatory responce of cancer cells.

Call: PRELUDIUM 9 , Panel: NZ1

Principal investigator: dr Ewelina Macech-Klicka

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Functional analysis of HSPB8 i model organisms (Danio rerio, Drosophila melanogaster): getting insights into HSPB8-linke...

Call: SONATA 7 , Panel: NZ4

Principal investigator: dr Magda Dubińska-Magiera

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Transient protein states in designing small-molecule inhibitors of protein-protein interactions

Call: SYMFONIA 2 , Panel: NZ1

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Investigation of MCPIP1 transcript function using smRNA FISH. Role of MCPIP1 protein in the regulation of inflammation.

Call: PRELUDIUM 4 , Panel: NZ1

Principal investigator: Jakub Andrzej Kochan

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Theoretical model of SH2-dependent STAT1 dimerization as a novel tool to identify specific compounds of functional inhib...

Call: PRELUDIUM 4 , Panel: NZ2

Principal investigator: Małgorzata Szeląg

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Synthesis of protein fragments of pathogens mimics human proteins and their use in diagnosis and prognosis of rheumatoid...

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: Inga Relich

Politechnika Łódzka, Wydział Chemiczny

Epicutaneous (EC) application of a protein antigen as a new method to treat collagen induced arthritis (CIA) in humanize...

Call: OPUS 2 , Panel: NZ6

Principal investigator: prof. Marian Szczepanik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Nauk o Zdrowiu

StAR protein trafficking of pro-atherogenic cholesterol hydroperoxides in macrophages

Call: OPUS 1 , Panel: NZ3

Principal investigator: dr hab. Witold Korytowski

Uniwersytet Jagielloński