Projects funded by the NCN

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58 projects found matching your search criteria :

  1. Physicochemical and structural study on the influence of charged amino acidic residues presence in the sequence in stabi...

    Call: SONATA 1 , Panel: ST4

    Principal investigator: dr Joanna Makowska

    Uniwersytet Gdański, Wydział Chemii

  2. Assessment of the state and function of the brain cholinergic system in animal models of Alzheimer-type and frontotempor...

    Call: OPUS 8 , Panel: NZ4

    Principal investigator: dr hab. Grażyna Niewiadomska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  3. Search for early molecular mechanisms and markers of preclinical stage of sporadic form of Alzheimer's disease (SAD) in ...

    Call: SONATA 8 , Panel: NZ4

    Principal investigator: dr Anna Mietelska-Porowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  4. Molecular basis of amyloidogenesis - structure of conformational dynamics slected complexes of human prion protein PrPc ...

    Call: OPUS 8 , Panel: ST4

    Principal investigator: prof. Maciej Kozak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  5. New protein bilayer system based on antigen-antibody interactions - is situ physicochemical characteristics

    Call: SONATA 7 , Panel: ST4

    Principal investigator: dr Monika Wasilewska

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  6. Structural and biophysical characteristics of highly conserved zinc hook domain of Rad50 protein - Studies on stability ...

    Call: OPUS 7 , Panel: NZ1

    Principal investigator: dr hab. Artur Krężel

    Uniwersytet Wrocławski, Wydział Biotechnologii

  7. Functional analysis of HSPB8 i model organisms (Danio rerio, Drosophila melanogaster): getting insights into HSPB8-linke...

    Call: SONATA 7 , Panel: NZ4

    Principal investigator: dr Magda Dubińska-Magiera

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  8. Structural and dynamic aspect of the electrostatic interaction in HIV-1 protease.

    Call: PRELUDIUM 7 , Panel: ST4

    Principal investigator: Prashant Kumar

    Uniwersytet Warszawski, Wydział Chemii

  9. Transient protein states in designing small-molecule inhibitors of protein-protein interactions

    Call: SYMFONIA 2 , Panel: NZ1

    Principal investigator: prof. Tadeusz Holak

    Uniwersytet Jagielloński, Wydział Chemii

  10. New high dimensional NMR methods for intrinsically disordered proteines investigation.

    Call: PRELUDIUM 6 , Panel: ST4

    Principal investigator: Szymon Żerko

    Uniwersytet Warszawski, Wydział Chemii

  11. Modeling realistic tear film structure including tear protein and analyzing its role in stability and biophysical proper...

    Call: PRELUDIUM 6 , Panel: ST7

    Principal investigator: Alicja Wizert

    Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

  12. Protein stability in aqueous solutions of osmolytes studied through complementary theoretical and experimental approach

    Call: OPUS 6 , Panel: NZ1

    Principal investigator: prof. Janusz Stangret

    Politechnika Gdańska, Wydział Chemiczny

  13. Investigation of MCPIP1 transcript function using smRNA FISH. Role of MCPIP1 protein in the regulation of inflammation.

    Call: PRELUDIUM 4 , Panel: NZ1

    Principal investigator: Jakub Kochan

    Uniwersytet Jagielloński w Krakowie, Wydział Biochemii, Biofizyki i Biotechnologii

  14. Halogen Bonding in Protein-Ligand Complexes. Thermodynamics and Structural Studies on Rationally Selected Protein-Ligand...

    Call: OPUS 4 , Panel: ST4

    Principal investigator: prof. Jarosław Poznański

    Instytut Biochemii i Biofizyki PAN

  15. Theoretical model of SH2-dependent STAT1 dimerization as a novel tool to identify specific compounds of functional inhib...

    Call: PRELUDIUM 4 , Panel: NZ2

    Principal investigator: Małgorzata Szeląg

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  16. Revealing adsorption mechanisms of anisotropic proteins under well-defined transport conditions.

    Call: OPUS 4 , Panel: ST4

    Principal investigator: prof. Zbigniew Adamczyk

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  17. Proteins at solid interfaces and proteinic structures in simulations and experiment

    Call: OPUS 1 , Panel: ST3

    Principal investigator: prof. Marek Cieplak

    Instytut Fizyki PAN

  18. Exploration of zinc proteome - Identification and characterization of new zinc domains and their function in stabilizati...

    Call: SONATA BIS 2 , Panel: NZ1

    Principal investigator: dr hab. Artur Krężel

    Uniwersytet Wrocławski, Wydział Biotechnologii

  19. Assessment of protective immunity against fasciolosis through vaccination of sheep with a multivalent stage-specific rec...

    Call: HARMONIA 3 , Panel: NZ6

    Principal investigator: dr Luke Norbury

    Instytut Parazytologii im. Witolda Stefańskiego PAN

  20. Synthesis of protein fragments of pathogens mimics human proteins and their use in diagnosis and prognosis of rheumatoid...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: Inga Relich

    Politechnika Łódzka, Wydział Chemiczny

  21. Biological mechanism of resting state raft formation and their participation in the regulation of certain cellular funct...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: prof. Aleksander Sikorski

    Uniwersytet Wrocławski, Wydział Biotechnologii

  22. Studies of the processes of aggregation of GAPDH and other proteins participating in neurodegenerative diseases, induced...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: prof. Grzegorz Bartosz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska, Katedra Biofizyki Molekularnej

  23. The role of Maf1 protein, repressor of Pol III RNA, in controlling tRNA stabilization

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: dr Tomasz Turowski

    Politechnika Warszawska, Wydział Chemiczny

  24. Exotic beta-sheet conformations in chiral superstructures of peptide fibrils

    Call: OPUS 2 , Panel: ST4

    Principal investigator: dr hab. Wojciech Dzwolak

    UNIWERSYTET WARSZAWSKI, Wydział Chemii

  25. Epicutaneous (EC) application of a protein antigen as a new method to treat collagen induced arthritis (CIA) in humanize...

    Call: OPUS 2 , Panel: NZ6

    Principal investigator: prof. Marian Szczepanik

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Nauk o Zdrowiu

  26. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  27. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

    Call: OPUS 24 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  28. Inhibition of protein disulfide isomerases as a strategy for reduction of prothrombotic state in atherosclerosis; therap...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Kamil Przyborowski

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  29. Ancestral traits and genomic innovations in early diverging fungi - implications for mucormycosis

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: dr hab. Anna Muszewska

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  30. Why cells become smaller to survive? Analysis of tobacco BY2 cells adapted to osmotic and salt stress in the search of k...

    Call: OPUS 20 , Panel: NZ9

    Principal investigator: dr Agnieszka Szuba

    Instytut Dendrologii Polskiej Akademii Nauk

  31. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  32. Astrocytes-regulated oligomerization state of fructose bisphosphatase 2 (FBP2) in neurons as a basic factor regulating m...

    Call: OPUS 19 , Panel: NZ4

    Principal investigator: prof. Dariusz Rakus

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  33. Protein S-nitrosation as a trigger for DNA leakage from the nucleus: in the quest for a mechanism

    Call: PRELUDIUM 18 , Panel: NZ3

    Principal investigator: Aleksandra Kopacz

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  34. Inhibitors of serine proteases as regulators of dendritic cell function.

    Call: MAESTRO 1 , Panel: NZ5

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  35. Platelets in the Uremic Milieu – The link between protein carbamylation and platelet dysfunctions in end stage renal dis...

    Call: OPUS 17 , Panel: NZ4

    Principal investigator: dr hab. Piotr Mydel

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  36. Novel methods for structural biology of large symmetric protein assemblies by solid-state Nuclear Magnetic Resonance (NM...

    Call: OPUS 17 , Panel: ST4

    Principal investigator: dr Jan Stanek

    Uniwersytet Warszawski, Wydział Chemii

  37. Interaction of iron ions with heat shock protein B1.

    Call: SONATA 14 , Panel: ST4

    Principal investigator: dr Agnieszka Szebesczyk

    Uniwersytet Opolski

  38. The effect of nitric oxide on histone protein acetylation status in Phytophthora infestans (Mont.) de Bary

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: dr hab. Magdalena Arasimowicz-Jelonek

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  39. The effect of thiol redox regulators on seed quality and the aging process

    Call: OPUS 16 , Panel: NZ9

    Principal investigator: dr hab. Ewelina Ratajczak

    Instytut Dendrologii Polskiej Akademii Nauk

  40. Mechanistic insights into the specificity of glycosaminoglycan interactions with regulatory proteins

    Call: BEETHOVEN 3 , Panel: ST4

    Principal investigator: dr hab. Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  41. Molecular mechanisms of signaling lipid recognition in the membrane: phosphatidic acid and ceramide-1-phosphate

    Call: SONATA BIS 8 , Panel: NZ1

    Principal investigator: dr hab. Aleksander Czogalla

    Uniwersytet Wrocławski, Wydział Biotechnologii

  42. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr...

    Call: SONATINA 2 , Panel: NZ7

    Principal investigator: dr Sabina Podlewska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  43. Enhancing resolution and predictive power of the UNRES force field for protein folding simulations by revision of the po...

    Call: PRELUDIUM 1 , Panel: ST4

    Principal investigator: dr Adam Sieradzan

    Uniwersytet Gdański, Wydział Chemii

  44. The self-assembly of superstructures of peptidic nanofibrils controlled by conformational memory effect

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Wojciech Dzwolak

    Instytut Wysokich Ciśnień Polskiej Akademii Nauk

  45. Role of RNase activity of MCPIP1 protein in neuroblastoma suppression.

    Call: PRELUDIUM 13 , Panel: NZ1

    Principal investigator: dr Iwona Nowak

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  46. Structural determinants of optical control of insulin and neuroligin release by photoactive protein ligands.

    Call: OPUS 12 , Panel: ST4

    Principal investigator: prof. Wiesław Nowak

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  47. The role of the ESCRT-0 protein complex in viral RNA-dependent activation of TLR3 signaling in murine astrocytes

    Call: PRELUDIUM 12 , Panel: NZ6

    Principal investigator: Matylda Mielcarska

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Medycyny Weterynaryjnej

  48. Mechanism of substrate recognition and binding by gamma-secretase on the example of the amyloid precursor protein

    Call: PRELUDIUM 12 , Panel: ST4

    Principal investigator: Łukasz Nierzwicki

    Politechnika Gdańska, Wydział Chemiczny

  49. Detailed mechanism of resting state membrane raft formation via dissecting the MPP1-flotillins/lipids interactions in vi...

    Call: OPUS 11 , Panel: NZ1

    Principal investigator: dr hab. Aleksander Czogalla

    Uniwersytet Wrocławski, Wydział Biotechnologii

  50. Modification of biological and tribological properties of Ti6Al4V titanium alloy and composite material on the basis of ...

    Call: OPUS 1 , Panel: ST8

    Principal investigator: prof. Tadeusz Wierzchoń

    Politechnika Warszawska, Wydział Inżynierii Materiałowej

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