Projects funded by the NCN

Fentanyl opioid designer drugs: from molecular modeling to in vitro studies

Call: OPUS 6 , Panel: ST4

Principal investigator: prof. Joanna Sadlej

Narodowy Instytut Leków

Structure-activity relationship of bifunctional peptides, agonists of opioid receptors and antagonists of neurokinin rec...

Call: PRELUDIUM 2 , Panel: ST5

Principal investigator: Jolanta Dyniewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Sławomir Filipek

Uniwersytet Warszawski, Wydział Chemii

The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

Call: OPUS 23 , Panel: NZ7

Principal investigator: dr Katarzyna Szczepańska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Anna Piotrowska-Murzyn

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Neurobiological mechanisms of migraine pain - role of opioid and NOP systems

Call: SONATA BIS 11 , Panel: NZ7

Principal investigator: dr Katarzyna Targowska-Duda

Uniwersytet Medyczny w Lublinie

Role of opioid receptors in arterial hypertension. Examination of hypotensive action of biphalin, a synthetic non-addtic...

Call: OPUS 2 , Panel: NZ4

Principal investigator: prof. Janusz Sadowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr Jan Rodriguez Parkitna

Instytut Farmakologii PAN

Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr hab. Maciej Sałaga

Uniwersytet Medyczny w Łodzi

Investigation of novel functionally selective opioid receptors agonists

Call: ETIUDA 8 , Panel: NZ7

Principal investigator: Łucja Kudła

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Kappa opioid receptors integrate neuronal signaling involved in social behavior

Call: OPUS 18 , Panel: NZ7

Principal investigator: dr hab. Jan Rodriguez Parkitna

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – foc...

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Marta Zielińska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Effects of a novel nonaddictive opioid on response to stress

Call: PRELUDIUM 17 , Panel: NZ7

Principal investigator: Łucja Kudła

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Rational design and evaluation of functionally biased opioid agonists

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Ryszard Przewłocki

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Searching for mu opioid receptor peptide agonists with G protein/beta-arrestin biased profile and their pharmacological ...

Call: SONATA 14 , Panel: ST5

Principal investigator: dr Justyna Piekielna-Ciesielska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 ...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: dr Klaudia Kwiatkowski

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Barbara Przewłocka

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

MOLECULAR DETERMINANTS OF SIGNAL PROPAGATION IN THE DELTA AND MU OPIOID RECEPTORS - IN SEARCH FOR ANALGETICS WITH LESS S...

Call: PRELUDIUM 14 , Panel: NZ2

Principal investigator: Tomasz Stepniewski

Uniwersytet Warszawski, Wydział Chemii

Gene and protein analysis of OPRM1/MOR and OPRK1/KOR opioid receptors expression and neurobiological marker of nerve ter...

Call: PRELUDIUM 1 , Panel: NZ4

Principal investigator: Piotr Kupczyk

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple recept...

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Anna Janecka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski