Projects funded by the NCN

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q...

Call: OPUS 21 , Panel: NZ2

Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej PAN

Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Weronika Paulina Kotkowiak

Instytut Chemii Bioorganicznej PAN

Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr hab. Maciej Stawnisław Sałaga

Uniwersytet Medyczny w Łodzi

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

Novel bispecific G-quadruplex conjugates as potential anticancer agents

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: dr Carolina Sofia Pereira Roxo

Instytut Chemii Bioorganicznej PAN

Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

Call: SONATA 14 , Panel: NZ7

Principal investigator: dr Artur Wnorowski

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr...

Call: SONATINA 2 , Panel: NZ7

Principal investigator: dr Sabina Marta Podlewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Structural determinants of anticancer properties of G-rich oligonucleotides

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

The effect of membrane domains on the G protein-lipid interactions

Call: OPUS 12 , Panel: NZ1

Principal investigator: dr Agnieszka Polit

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Agents affecting the rate of food tolerance development in children with cow's milk protein allergy

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Małgorzata Kaczorowska

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Nauk o Zdrowiu

Molecular mechanism of unique action of clozapine in the context of GPCR.

Call: OPUS 8 , Panel: NZ7

Principal investigator: dr Agata Faron-Górecka

Instytut Farmakologii PAN

Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

Call: SONATA 4 , Panel: NZ1

Principal investigator: dr Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Interaction of dopamine receptors with G proteins – structural and kinetic aspects

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr Agnieszka Polit

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii