Projects funded by the NCN

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199 projects found matching your search criteria :

  1. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Rafał Kurczab

    Instytut Farmakologii PAN

  2. The effect of typical and atypical neuroleptics on the expression of cytochrome P450 isoenzymes 1A2 (CYP1A2) and 3A4 (CY...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Basińska-Ziobroń

    Instytut Farmakologii PAN

  3. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii PAN

  4. Reinforcement sensitivity phenotypes as determinants of various motivational styles of alcohol drinking: craving for rew...

    Call: OPUS 28 , Panel: HS6

    Principal investigator: prof. Rafał Ryguła

    Instytut Farmakologii PAN

  5. Design and Pharmacological Evaluation of Marine Alkaloid-Inspired 5-HT2A Receptor Ligands

    Call: PRELUDIUM 24 , Panel: NZ1

    Principal investigator: Szymon Kazimierz Kordylewski

    Instytut Farmakologii PAN

  6. Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Katarzyna Elżbieta Głombik

    Instytut Farmakologii PAN

  7. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Michał Józef Wilczkowski

    Instytut Farmakologii PAN

  8. Novel hope for diseased joints: a polymer-based treatment to promoteregenerative strategies for patients with osteoarthr...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Marta Kędziora

    Instytut Farmakologii PAN

  9. Biological roles of transcriptional networks activated in the brain by psychotropic drugs

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Michał Korostyński

    Instytut Farmakologii PAN

  10. Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mech...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr hab. Bernadeta Szewczyk

    Instytut Farmakologii PAN

  11. The role of astrocytes and cellular metabolism in functional compensation of degeneration of dopaminergic system in the ...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Katarzyna Kuter

    Instytut Farmakologii PAN

  12. Neurobiological basis of sensation seeking behaviour

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Magdalena Maria Sikora

    Instytut Farmakologii PAN

  13. Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Jolanta Sowa-Kućma

    Instytut Farmakologii PAN

  14. "Legal Higsh"- CNS effects and neurotoxicity

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Krystyna Czesława Gołembiowska

    Instytut Farmakologii PAN

  15. Noradrenergic modulation of cocaine-seeking

    Call: SONATA 6 , Panel: NZ4

    Principal investigator: dr Wojciech Barnaba Solecki

    Instytut Farmakologii PAN

  16. Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha...

    Call: PRELUDIUM 7 , Panel: NZ6

    Principal investigator: Katarzyna Curzytek

    Instytut Farmakologii PAN

  17. Neuroplasticity regulation by alternative gene transcription

    Call: SONATA 2 , Panel: NZ3

    Principal investigator: dr Michał Korostyński

    Instytut Farmakologii PAN

  18. The molecular basis of stress-induced anxiety and affective disorders

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr Michał Korostyński

    Instytut Farmakologii PAN

  19. Glucocorticoid-induced alterations of astrocytic metabolism in stress-related disorders.

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: dr Michał Wiesław Ślęzak

    Instytut Farmakologii PAN

  20. The influence of molecular fingerprint bit density on chemical pattern recognition effectiveness

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: Rafał Jerzy Kurczab

    Instytut Farmakologii PAN

  21. Molecular mechanism of interactions between GPCRs and G protein.

    Call: PRELUDIUM 10 , Panel: NZ2

    Principal investigator: Stefan Mateusz Mordalski

    Instytut Farmakologii PAN

  22. Development of protocol for in silico design of compounds inhibit Ebola virus infection

    Call: PRELUDIUM 11 , Panel: NZ2

    Principal investigator: Dawid Zdzisław Warszycki

    Instytut Farmakologii PAN

  23. Pharmacological properties and neurotoxicity of novel NBOMe derivatives

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Krystyna Czesława Gołembiowska

    Instytut Farmakologii PAN

  24. The role of the endogenuous opioid system in prosocial behavior

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  25. Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Zofia Maria Rogóż

    Instytut Farmakologii PAN

  26. Comparative effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) and olanzapine on the cognitive dysfunction meas...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Wąsik

    Instytut Farmakologii PAN

  27. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  28. The effect of chronic treatment with iasenapine and iloperidone on the expression and activity of cytochrome P450 in the...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Przemysław Jan Danek

    Instytut Farmakologii PAN

  29. Effects of a novel nonaddictive opioid on response to stress

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: dr Łucja Elżbieta Szumiec

    Instytut Farmakologii PAN

  30. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii PAN

  31. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Justyna Beata Barut

    Instytut Farmakologii PAN

  32. Effects of prenatal stress on properities of neurons and synaptic transmission in dorsal raphe nucleus of the rat

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Joanna Grażyna Sowa

    Instytut Farmakologii PAN

  33. Unusual 5-HT6 receptor ligands

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  34. Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Krystyna Czesława Gołembiowska

    Instytut Farmakologii PAN

  35. The effect of omega-3 fatty acid-enriched diet on the myelination impairment and the depression-like phenotype induced b...

    Call: SONATA 16 , Panel: NZ5

    Principal investigator: dr Irena Maria Smaga-Maślanka

    Instytut Farmakologii PAN

  36. Impact of pharmacogenetic profiles on depression treatment outcomes

    Call: SONATINA 5 , Panel: NZ2

    Principal investigator: dr Małgorzata Maria Borczyk

    Instytut Farmakologii PAN

  37. Investigation of novel functionally selective opioid receptors agonists

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Łucja Elżbieta Szumiec

    Instytut Farmakologii PAN

  38. A premotor disease signature for ALS

    Call: JPco-fuND2 Call 2021 , Panel: NZ7

    Principal investigator: dr Wojciech Kuban

    Instytut Farmakologii PAN

  39. New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii PAN

  40. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  41. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Bartłomiej Pochwat

    Instytut Farmakologii PAN

  42. Genetics of GR-dependent behavioral traits in humans

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Michał Korostyński

    Instytut Farmakologii PAN

  43. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  44. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  45. Plasticity of neuroanatomically identified synaptic inputs and functions of the dorsal raphe nucleus in an animal model ...

    Call: OPUS 25 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii PAN

  46. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

    Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

    Principal investigator: dr hab. Anna Ludwika Haduch

    Instytut Farmakologii PAN

  47. Effects of ketamine optical isomers on motivation and decision-making in rats using deep learning for behavioral analysi...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Natalia Alicja Malikowska-Racia

    Instytut Farmakologii PAN

  48. Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Barbara Wanda Chruścicka-Smaga

    Instytut Farmakologii PAN

  49. The role of glucocorticoids in the regulaton of neurodegenerative prosses

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Anna Jadwiga Kurek

    Instytut Farmakologii PAN

  50. The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Joanna Solich

    Instytut Farmakologii PAN

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