Projects funded by the NCN

Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte...

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: dr Magdalena Anna Kolasa

Instytut Farmakologii PAN

Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop...

Call: MAESTRO 3 , Panel: NZ4

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma

Call: SONATA 4 , Panel: NZ4

Principal investigator: dr Marta Ewa Kot

Instytut Farmakologii PAN

The role of the brain serotonergic system in the expression and activity of liver cytochrome P450.

Call: PRELUDIUM 4 , Panel: NZ7

Principal investigator: dr Marta Anna Rysz

Instytut Farmakologii PAN

Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

Call: OPUS 4 , Panel: NZ4

Principal investigator: dr Maciej Sławomir Kuśmider

Instytut Farmakologii PAN

The role of kynurenine pathway in neurophatic pain in view of innovative treatment approaches

Call: SONATA 9 , Panel: NZ4

Principal investigator: dr Ewelina Joanna Rojewska

Instytut Farmakologii PAN

The impact of early-life stress (maternal separation) and fluctuation in corticosterone levels during adolescence on pre...

Call: PRELUDIUM 9 , Panel: NZ4

Principal investigator: Iwona Magdalena Majcher-Maślanka

Instytut Farmakologii PAN

Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Call: HARMONIA 7 , Panel: NZ7

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

Call: PRELUDIUM 10 , Panel: NZ7

Principal investigator: Karolina Sylwia Podkowa

Instytut Farmakologii PAN

Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa...

Call: OPUS 11 , Panel: NZ4

Principal investigator: prof. Joanna Gabriela Mika

Instytut Farmakologii PAN

Characterisation of the orbitofrontal cortex dopamine D1 and D2 receptors' influence on rat's cognitive flexibility and ...

Call: PRELUDIUM 11 , Panel: NZ4

Principal investigator: Michał Dariusz Rychlik

Instytut Farmakologii PAN

Effects of chosen chemokines on the activity and synaptic transmission in central and basolateral complex of the amygdal...

Call: PRELUDIUM 11 , Panel: NZ4

Principal investigator: Joanna Ewa Sowa

Instytut Farmakologii PAN

The role of halogen bonding in interaction of ligands with SERT.

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Jakub Staroń

Instytut Farmakologii PAN

The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Anna Nikiforuk

Instytut Farmakologii PAN

Impact of early-life stress on maturation, permeability of blood brain-barrier and neuroinflammatory processes activatio...

Call: PRELUDIUM 12 , Panel: NZ4

Principal investigator: Anna Katarzyna Solarz

Instytut Farmakologii PAN

Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

Call: OPUS 12 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Brain GABAB receptors as determinants of obesity phenotypes: evaluation of adolescent female and male rats

Call: OPUS 22 , Panel: NZ5

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii PAN

Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

Call: OPUS 22 , Panel: HS6

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Cognitive impairment in chronic pain - CBD as the undervalued remedy.

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii PAN

The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: dr Magdalena Białoń

Instytut Farmakologii PAN

Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Władysława Anna Daniel

Instytut Farmakologii PAN

Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Bernadeta Angelika Pietrzak-Wawrzyńska

Instytut Farmakologii PAN

The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Agata Faron-Górecka

Instytut Farmakologii PAN

Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

Call: HARMONIA 9 , Panel: NZ7

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 ...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: dr Klaudia Kwiatkowski

Instytut Farmakologii PAN

The role of cognitive bias in individual vulnerability to to the transition from controlled use to uncontrolled abuse of...

Call: OPUS 16 , Panel: NZ7

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

Call: OPUS 16 , Panel: NZ2

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

The role of epigenetic readers from BET family in the emergence and treatment of schizophrenia-like abnormalities in a n...

Call: OPUS 16 , Panel: NZ4

Principal investigator: prof. Marzena Małgorzata Maćkowiak

Instytut Farmakologii PAN

The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni...

Call: PRELUDIUM 16 , Panel: NZ7

Principal investigator: dr Paulina Agnieszka Cieślik

Instytut Farmakologii PAN

Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

Call: OPUS 18 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

Instytut Farmakologii PAN

In vivo effects, underlying signaling pathways and mechanism of action of ghrelin receptor agonist against pathological ...

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Piotr Chmielarz

Instytut Farmakologii PAN

Fluorine substitution – a new algorithm for increasing biological activity

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Wojciech Pietruś

Instytut Farmakologii PAN

Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

Call: SONATINA 4 , Panel: NZ7

Principal investigator: Katarzyna Anna Szczepańska

Instytut Farmakologii PAN

Maternal obesity as a risk factor of autism spectrum disorder in offspring - in search of the role of the gut microbiota...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr Dawid Mateusz Gawliński

Instytut Farmakologii PAN

New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Joanna Gabriela Mika

Instytut Farmakologii PAN

The role of the immune checkpoints in the pathomechanism of depressive disorders.

Call: OPUS 22 , Panel: NZ6

Principal investigator: prof. Marta Wanda Kubera

Instytut Farmakologii PAN

The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

Call: OPUS 5 , Panel: NZ7

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Effect of caffeine on neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine in the mouse brain.

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Anna Maria Górska

Instytut Farmakologii PAN

The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r...

Call: OPUS 6 , Panel: NZ4

Principal investigator: prof. Grzegorz Władysław Hess

Instytut Farmakologii PAN

Involvement of cyclooxygenase 2 in antidepressant-like effects of metabotropic glutamatergic receptors group I.

Call: SONATA 7 , Panel: NZ7

Principal investigator: dr Katarzyna Małgorzata Stachowicz

Instytut Farmakologii PAN

The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio...

Call: PRELUDIUM 8 , Panel: NZ7

Principal investigator: Agnieszka Teresa Potasiewicz

Instytut Farmakologii PAN

Neural substrates of decision making under risk and uncertainty: role of phasic activity of dopamine neurons

Call: PRELUDIUM 8 , Panel: NZ4

Principal investigator: Przemysław Eligiusz Cieślak

Instytut Farmakologii PAN

seQinspector - genome-wide analysis of gene transcription regulation mechanisms

Call: PRELUDIUM 1 , Panel: NZ2

Principal investigator: dr Marcin Piechota

Instytut Farmakologii PAN