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Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the context of obsessive-compulsive disorder

2012/05/N/NZ7/00664

Keywords:

paroxetine risperidone obsessive-compulsive disorder heterodimerization

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Kolasa 

Number of co-investigators in the project: 3

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 99 710 PLN

Project start date (Y-m-d): 2013-02-05

Project end date (Y-m-d): 2016-02-04

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. Paroxetine and low-dose risperidone induce serotonin 5-HT1A and dopamine D2 receptor heteromerization in the mouse prefrontal cortex
    Authors:
    Magdalena Kolasa, Joanna Solich, Agata Faron-Górecka, Dariusz Żurawek, Paulina Pabian, Sylwia Łukasiewicz, Maciej Kuśmider, Kinga Szafran-Pilch, Marta Szlachta, Marta Dziedzicka-Wasylewska
    Academic press:
    Neuroscience , Wydawca: Elsevier
    Status:
    Accepted for publication
    DOI:
    10.1016/j.neuroscience.2018.03.004 - link to the publication
  1. Effect of combined paroxetine and low-dose risperidone treatment on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptors in mice brain cortex
    Authors:
    Kolasa M., Solich J., Faron-Górecka A, Żurawek D., Pabian P., Szafran K., Kuśmider M., Dziedzicka-Wasylewska M.
    Conference:
    2nd Central European Biomedical Congress (CEBC) - " From emerging biochemical strategies to personalized medicine" (rok: 2016, ), Wydawca: CEBC 2016 Congress Office
    Data:
    konferencja 15-18 czerwca 2016
    Status:
    Accepted for publication
  2. Paroxetine and risperidone influence the level of heterodimers of dopamine D2 and serotonin 5-HT1A receptors in brain cortex neuronal cells
    Authors:
    Magdalena Kolasa, Kinga Szafran, Dariusz Żurawek, Agata Faron-Górecka, Joanna Solich, Paulina Pabian, Maciej Kuśmider, Marta Dziedzicka-Wasylewska
    Conference:
    NEURONUS 2016 (rok: 2016, ), Wydawca: Neuronus 2016 Organizing Comittee
    Data:
    konferencja 22-24 kwietnia 2016
    Status:
    Accepted for publication

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