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1. Obtaining of new quinoline derivatives with potential activity for serotonin receptors and inhibition of serotonin reupt…

Principal investigator: Przemysław Paweł Taciak

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: PRELUDIUM 5, Panel: NZ7

2. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr…

Principal investigator: dr Sabina Marta Podlewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATINA 2, Panel: NZ7

3. Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

Principal investigator: Patryk Pyka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

4. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: HARMONIA 7, Panel: NZ7

5. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto…

Principal investigator: dr Magdalena Joanna Zaniewska

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ4

6. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application…

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: PRELUDIUM 5, Panel: NZ2

7. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

Principal investigator: Grzegorz Marek Satała

Instytut Farmakologii PAN

Call: PRELUDIUM 3, Panel: NZ7

8. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search…

Principal investigator: prof. Marcin Roman Kołaczkowski

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 21, Panel: NZ7

9. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i…

Principal investigator: dr Agnieszka Wioleta Jankowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 13, Panel: NZ7

10. In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia…

Principal investigator: prof. Anna Małgorzata Wesołowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 1, Panel: NZ4

11. Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D…

Principal investigator: Kinga Maria Czarnota-Łydka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 21, Panel: NZ7

12. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni…

Principal investigator: dr Agata Siwek

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: SONATA 14, Panel: NZ7

13. The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot…

Principal investigator: Annamaria Teresa Lubelska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 11, Panel: NZ7

14. Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte…

Principal investigator: dr Magdalena Anna Kolasa

Instytut Farmakologii PAN

Call: PRELUDIUM 3, Panel: NZ7

15. The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

Principal investigator: prof. Andrzej Pilc

Instytut Farmakologii PAN

Call: MAESTRO 3, Panel: NZ7

16. Unusual 5-HT6 receptor ligands

Principal investigator: prof. Andrzej Jacek Bojarski

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

17. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl…

Principal investigator: dr Przemysław Patryk Zaręba

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Call: PRELUDIUM 19, Panel: NZ7

18. Thymol-derived 1,3,5-triazines, the non-indole and non-sulfone 5-HT6 receptor ligands, as a starter in search for an inn…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ7

19. Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

Principal investigator: dr hab. Jadwiga Handzlik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 9, Panel: NZ7

20. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

21. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

Principal investigator: dr Rafał Kurczab

Instytut Farmakologii PAN

Call: SONATA 8, Panel: NZ7

22. Synthesis and biological evaluation of pyrrolidine-2,5-dione derivatives as potential antidepressant agents.

Principal investigator: dr Andrzej Józef Chodkowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: OPUS 5, Panel: NZ7

23. Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi…

Principal investigator: dr hab. Maciej Stawnisław Sałaga

Uniwersytet Medyczny w Łodzi

Call: SONATA 16, Panel: NZ7

24. Cooperative involvement of serotonergic signaling and extracellular matrix in synaptic plasticity underlying the pathoge…

Principal investigator: dr hab. Jakub Mateusz Włodarczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: HARMONIA 3, Panel: NZ3

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