Projects funded by the NCN

Precisie quantum chemical calculations for light atomic and molecular systems

Call: OPUS 1 , Panel: ST4

Principal investigator: dr Mariusz Puchalski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

A new strategy to fight antibiotic resistance based on hybrids of fluoroquinolones and quaternary ammonium salts

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Joanna Dagmara Fedorowicz

Gdański Uniwersytet Medyczny

Janus nanoparticles - research on the effect of the duality of carriers of the activesubstance in targeted therapy of sk...

Call: OPUS 28 , Panel: ST8

Principal investigator: dr hab. Bożena Anna Tyliszczak

Politechnika Krakowska im. Tadeusza Kościuszki

Advancing Skeletal Muscle Tissue Engineering: Biologically Active Bioinks for Drug-Induced Disease Modelling and On-Dema...

Call: OPUS 28 , Panel: ST8

Principal investigator: prof. Wojciech Święszkowski

Politechnika Warszawska

In vitro cultures of Trifolium rubens L. – phytochemical, biotechnological studies and evaluation of biological activity...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Marta Karolina Klimek-Szczykutowicz

Uniwersytet Jana Kochanowskiego w Kielcach

New Horizons in Cancer Immunotherapy: Blocking LAG-3/FGL1 Interactions

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Jacek Plewka

Uniwersytet Jagielloński

Could fibroblast senescence and their resistance to apoptosis be the hidden drivers behind endometrial fibrosis in equin...

Call: OPUS 28 , Panel: NZ5

Principal investigator: dr Katarzyna Karolina Piotrowska-Tomala

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

Microbial degradation of cardiac drugs: discovering the degradation pathways of one of the most commonly used beta-block...

Call: SONATA 20 , Panel: NZ9

Principal investigator: dr Anna Maria Dzionek

Uniwersytet Śląski w Katowicach

"Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The first antibody-drug conjugates for Alzheimer's disease therapy

Call: SONATA BIS 14 , Panel: NZ5

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

Demonstration of the key role of vitamin B12 uptake in regulating Mycobacterium tuberculosis virulence lipids synthesis ...

Call: SONATA BIS 14 , Panel: NZ6

Principal investigator: dr Jakub Pawełczyk

Instytut Biologii Medycznej Polskiej Akademii Nauk

Molecular analyses of human dihydrouridine synthases acting on tRNA

Call: SONATA BIS 14 , Panel: NZ1

Principal investigator: dr Monika Ewelina Gaik

Uniwersytet Jagielloński

Supramolecular nanoparticles able to block calcium channels in cancer cells

Call: SONATA BIS 14 , Panel: ST11

Principal investigator: dr hab. Marek Brzeziński

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

The influence of tunicamycin analogues and mimetics on hepatitis C virus (HCV) propagation.

Call: PRELUDIUM 2 , Panel: NZ6

Principal investigator: dr Ewelina Król

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

Call: OPUS 27 , Panel: NZ5

Principal investigator: Kamila Ostrowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Biological activity of AmB: Are the dynamics of interaction with the cell membrane the key?

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Sebastian Janik

Uniwersytet Marii Curie-Skłodowskiej w Lublinie

Dual Se-containing 5-HT1A and 5-HT7 biased agonists activating sigma-1 receptor as a hope of finding fast-acting antidep...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Karolina Anna Pytka

Uniwersytet Jagielloński

Disruption of the posttranslational activation of the translation factor EF-P as a new target for antimicrobial agents.

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr Piotr Wilk

Uniwersytet Jagielloński

Strong bonds make perfect relationships. Covalent interactions between antibiotics and polymeric matrix as a key factor ...

Call: PRELUDIUM 23 , Panel: ST5

Principal investigator: Konrad Wojciech Kwiecień

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

Development of novel screening method for identifying xanthine oxidase inhibitors – towards new drug candidates for gout...

Call: PRELUDIUM 23 , Panel: ST4

Principal investigator: Monika Katarzyna Rola

Politechnika Łódzka

Nanocrystalline and amorphous light-weight complex concentrated alloys of Mg-Al-Ti-Fe-Cr type

Call: OPUS 27 , Panel: ST11

Principal investigator: dr hab. Marek Maciej Krasnowski

Politechnika Warszawska

Assessment of long-term effects of semaglutide administered in repeated short cycles in obese mice

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Jakub Łukasz Wojcieszak

Uniwersytet Medyczny w Łodzi

The role of gut microbiota in the treatment of epilepsy: experimental studies

Call: OPUS 27 , Panel: NZ4

Principal investigator: prof. Piotr Wiktor Wlaź

Uniwersytet Marii Curie-Skłodowskiej w Lublinie

Development of novel potential therapeutics in inflammatory bowel diseases based on nanoformulations employing senomodul...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Jakub Jerzy Fichna

Uniwersytet Medyczny w Łodzi

A Compound Screening Platform for the Discovery of Histone- and Nucleosome-Targeting Agents

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Curtis Davey

Uniwersytet Jagielloński

Electrochemically Induced Release Systems Based on Conductive Surfaces Modified with Electroactive Microgels

Call: PRELUDIUM 23 , Panel: ST5

Principal investigator: Paulina Adriana Gwardys

Uniwersytet Warszawski

Assessment of virulence, biofilm formation and drug-susceptibility of Candida albicans treated with plant essential oils...

Call: PRELUDIUM 1 , Panel: NZ6

Principal investigator: Aleksandra Budzyńska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

Innovative organocatalytic strategies in functionalization of drugs, natural products and biological compounds.

Call: PRELUDIUM 23 , Panel: ST4

Principal investigator: Kamil Dawid Hanek

Uniwersytet im. Adama Mickiewicza w Poznaniu

EGR1 Protein: A Key Factor in Cellular Homeostasis?

Call: PRELUDIUM 23 , Panel: NZ3

Principal investigator: Marta Leśniczak-Staszak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Role of mitochondrial DNA damage and repair in the resistance of BCR/ABL-expressing cells to imatinib

Call: OPUS 2 , Panel: NZ2

Principal investigator: prof. Janusz Błasiak

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Stealth" asparaginases as improved protein drugs for the treatment of childhood acute lymphoblastic leukemia (ALL)

Call: OPUS 27 , Panel: NZ1

Principal investigator: prof. Matthias Bochtler

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

Impact of cytostatic drugs present in the environment on Gram-negative bacteria: mechanisms of adaptation and implicatio...

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Adam Grzywaczyk

Politechnika Poznańska

Development of technology for producing emulsions stabilized using biosurfactants dissolved in the oil phase. Increasing...

Call: OPUS 27 , Panel: ST8

Principal investigator: dr hab. Marcel Krzan

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera Polskiej Akademii Nauk

Coating dextran nanocarriers with immune cell membranes as a way to transport active substances across the blood-brain b...

Call: PRELUDIUM 23 , Panel: ST11

Principal investigator: Daniel Filip Wyleziński

Politechnika Warszawska

New functional MOF@hydroxyapatite composites for the treatment of bacterial bone infections

Call: PRELUDIUM 23 , Panel: ST11

Principal investigator: Weronika Bodylska

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego Polskiej Akademii Nauk

Development and characterization of novel multitargeted organometallic tubulin polymerization inhibitors for enhancing t...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Damian Nestor Plażuk

Uniwersytet Łódzki

Analytical methods for the determination of contaminants in dairy products using electrochemical multisensors platform w...

Call: DAINA 3 , Panel: NZ7

Principal investigator: dr Krzysztof Robert Noworyta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Stimuli-Responsive Metal-Organic Frameworks: Structural Dynamics and Sorption Properties

Call: SONATINA 8 , Panel: ST5

Principal investigator: dr Marzena Pander

Uniwersytet Jagielloński

Manufacture of a new generation three-dimensional "drug-on-chip" materials with controlled release of active agents dedi...

Call: SONATINA 8 , Panel: ST8

Principal investigator: dr Wiktoria Dominika Tomal

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera Polskiej Akademii Nauk

Stimuli-responsive anion transporters for targeted drug delivery

Call: OPUS 26 , Panel: ST5

Principal investigator: dr hab. Michał Jan Chmielewski

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Eutectic composition as an innovative approach for tackling the limited physical stability problem of amorphous pharmace...

Call: OPUS 26 , Panel: ST5

Principal investigator: prof. Marian Wilhelm Paluch

Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Agnieszka Wnuk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Experimental and numerical explanation of solidification behavior, hot deformability and brittleness phenomena in lightw...

Call: OPUS 26 (LAP) , Panel: ST11

Principal investigator: prof. Adam Szczepan Grajcar

Politechnika Śląska, Wydział Mechaniczny Technologiczny

Activation of Staphylococcus aureus LytM autolysin as a potential target for antimicrobials development.

Call: OPUS 26 , Panel: NZ1

Principal investigator: dr hab. Izabela Sabała

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Taming aggregation with AmyloGraph 2.0: a database and prediction models of amyloid self-assembly modulators

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Michał Jan Burdukiewicz

Uniwersytet Medyczny w Białymstoku

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Classification of treatment processes of wastewater containing antimicrobial drugs based on changes in their micriobial ...

Call: SONATA 2 , Panel: NZ7

Principal investigator: dr hab. Wojciech Baran

Śląski Uniwersytet Medyczny w Katowicach, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej w Sosnowcu

Synthesis, characterization, and evaluation of the biological activity of innovative thermosensitive suppositories compr...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Ewa Olędzka

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Tumor viscoelasticity as a central player in glioblastoma treatment - towards mechanopharmacology

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk