Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The influence of tunicamycin analogues and mimetics on hepatitis C virus (HCV) propagation.

2011/03/N/NZ6/00059

Keywords:

hepatitis C virus glycoproteins tunicamycin antivirals

Descriptors:

  • NZ6_5: Virology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ewelina Król 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 397 000 PLN

Project start date (Y-m-d): 2012-08-06

Project end date (Y-m-d): 2016-08-05

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Moduł pomiarów luminescencji dwubarwnej z systemem liczenia fotonów (42 000 PLN)
  2. Wytrząsarka (kołyska) laboratoryjna (4 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Wirusowe zapalenie wątroby typu C – nowe metody leczenia i zapobiegania
    Authors:
    Alicja Chmielewska, Małgorzata Rychłowska, Ewelina Król, Karolina Solarz, Krystyna Bieńkowska-Szewczyk
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2015, tom: 69, strony: 946-963), Wydawca: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/17322693.1165197. - link to the publication
  2. Novel glycoconjugates, derivatives of 4-aminophenyl 1-thioglycosides, as potential antiviral compounds
    Authors:
    Ewelina Krol, Gabriela Pastuch-Gawolek, Binay Chaubey, Gabriela Brzuska, Karol Erfurt, Boguslaw Szewczyk
    Academic press:
    Molecules (rok: 2018, ), Wydawca: MDPI
    Status:
    Submitted
  3. Synthesis and antiviral activity of a novel glycosyl sulfoxide against classical swine fever virus
    Authors:
    Ewelina Krol, Gabriela Pastuch-Gawolek, Dawid Nidzworski, Michal Rychlowski, Wieslaw Szeja, Grzegorz Grynkiewicz, Boguslaw Szewczyk
    Academic press:
    Bioorganic & Medicinal Chemistry (rok: 2014, tom: 22, strony: 2662-2670), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bmc.2014.03.027 - link to the publication
  4. Novel thioglycosyl analogs of glycosyltransferase substrates as antiviral compounds against classical swine fever virus and hepatitis C virus
    Authors:
    Gabriela Pastuch-Gawolek, Binay Chaubey, Boguslaw Szewczyk, Ewelina Krol
    Academic press:
    European Journal of Medicinal Chemistry (rok: 2017, tom: 137, strony: 247-262), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejmech.2017.05.051 - link to the publication
  5. Anti-hepatitis C virus activity of uridine derivatives of 2-deoxy sugars
    Authors:
    Ewelina Krol, Ilona Wandzik, Gabriela Pastuch-Gawolek, Boguslaw Szewczyk
    Academic press:
    Molecules (rok: 2018, ), Wydawca: MDPI
    Status:
    Submitted