Eutectic composition as an innovative approach for tackling the limited physical

Eutectic composition as an innovative approach for tackling the limited physical stability problem of amorphous pharmaceuticals

2023/51/B/ST5/02317

Keywords

Descriptors

NZ7_14: Farmacja, farmakoterapia, farmakologia
ST3_13: Struktura i dynamika układów nieuporządkowanych, miękka materia itp.
ST5_06: Materiały porowate, ceramiczne, szkła

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Voivodeship: śląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Marian Wilhelm Paluch

Number of co-investigators in the project: 5

Call

OPUS 26 – announced on 2023-09-18

Amount awarded: 1 999 946 PLN
Project start date: 2024-08-01
Project end date: 2028-07-31
Project duration: 48 months (the same as in the proposal)
Project status: Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

High-Pressure Dielectric Spectroscopic Studies of Amorphous CBD: Investigating Molecular Dynamics and Physical Stability Under Manufacturing Conditions of the Pharmaceuticals

Authors:
Mariya Mathew, Justyna Knapik-Kowalczuk, Mateusz Dulski, Marian Paluch

Academic press:
Pharmaceutics (year: 2025, volume: 17(3), 358, pages: 46039), Publisher: mdpi

Status:
Published

DOI:
10.3390/pharmaceutics17030358 – link to the publication
Eutectic Coamorphous System of Enzalutamide and Acetyl Maltose: A Strategy for Improved Physical Stability and Aqueous Solubility

Authors:
Julia Cichocka-Łokuciejewska, Justyna Knapik-Kowalczuk, Mateusz Dulski, Katarzyna Ewa Greber, Wiesław Sawicki, Marian Paluch

Academic press:
Mol. Pharmaceutics (year: 2026, volume: jeszcze nie nadano, pages: jeszcze nie nadano), Publisher: ACS

Status:
Published

DOI:
10.1021/acs.molpharmaceut.5c01164 – link to the publication

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