Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The effect of prolonged treatment with the new antipsychotics brexpiprazole and lumateperone on human liver function using in vitro model of 3D hepatocyte spheroids

2023/51/B/NZ4/01847

Keywords:

hepatocytes spheroids liver antipsychotic drugs cytochrome P450 transcriptional factors

Descriptors:

  • NZ4_4: Pathophysiology
  • NZ4_11: Metabolism
  • NZ7_12: Prevention of human diseases

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Przemysław Danek 

Number of co-investigators in the project: 5

Call: OPUS 26 - announced on 2023-09-18

Amount awarded: 2 505 758 PLN

Project start date (Y-m-d): 2024-07-24

Project end date (Y-m-d): 2028-07-23

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.