Projects funded by the NCN


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14 projects found matching your search criteria :

  1. Comprehensive analysis of the therapeutic potential of oligonucleotides for the treatment of polyglutamine diseases

    Call: SONATA 9 , Panel: NZ5

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej PAN

  2. MIST: Artificial intelligence-assisted design of experiments as a tool to streamline the development of siRNA-lipid nano...

    Call: OPUS 29 , Panel: NZ7

    Principal investigator: dr hab. Paulina Krystyna Skupin-Mrugalska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  3. Molecular Pathogenesis and Precision Antisense Oligonucleotide Therapy for BAG3-Related Myofibrillar Myopathy Type 6 Usi...

    Call: OPUS 29 , Panel: NZ2

    Principal investigator: dr Estera Elmira Rintz

    Uniwersytet Gdański

  4. Evaluation of the therapeutic potential of synthetic miRNA-223-3p analog in a rat model of severe asthma

    Call: SONATA 19 , Panel: NZ4

    Principal investigator: dr Wojciech Jerzy Langwiński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  5. Targeting IGH enhancer RNAs as a therapeutic approach in B-cell lymphoma

    Call: SONATA BIS 13 , Panel: NZ1

    Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

    Instytut Genetyki Człowieka PAN

  6. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Alex Jun Matsuda

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  7. Identification and therapeutic targeting of the mRNA splicing alteration mechanisms driven by gain-of-function TP53 muta...

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Magdalena Oroń

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  8. Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

    Call: MAESTRO 12 , Panel: NZ3

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  9. Therapeutic activation and signalling determinants of the autoregulatory MBNL1 expression in myotonic dystrophy.

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr Ewa Agnieszka Stępniak-Konieczna

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

  10. Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of...

    Call: OPUS 17 , Panel: NZ1

    Principal investigator: dr Renata Joanna Grzela

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  11. How dysfunction in the nuclear, RNA degrading enzyme DIS3 leads to mitotic defects creating a possible therapeutic strat...

    Call: SONATINA 3 , Panel: NZ2

    Principal investigator: dr Tomasz M. Kuliński

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  12. Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets ...

    Call: OPUS 16 , Panel: NZ5

    Principal investigator: prof. Marzena Magdalena Gajęcka

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  13. Cotranscriptional folding of influenza virus RNA in MDCK cells in presence of antisense oligonucleotides. A new method f...

    Call: OPUS 13 , Panel: NZ1

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej PAN

  14. Chemically modified mRNA for studies on cellular processes and therapeutic applications

    Call: OPUS 11 , Panel: ST5

    Principal investigator: prof. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego