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15 projects found matching your search criteria:

  1. 1. Novel insights into inhibition of PD-L1/PD-1 immune checkpoint – discovery and optimization of covalent PD-L1 inhibitors…

    Principal investigator: dr Radosław Dariusz Kitel

    Uniwersytet Jagielloński

    Call: SONATA 20, Panel: ST5

  2. 2. Controlling the covalent activity of a PD-L1 inhibitors with light

    Principal investigator: Wiktor Jan Uzar

    Uniwersytet Jagielloński

    Call: PRELUDIUM 23, Panel: NZ7

  3. 3. Photoswitchable and chimeric molecules for spatially restricted and endoplasmic reticulum-specific blockade of PD-L1 pro…

    Principal investigator: dr Łukasz Dariusz Skalniak

    Uniwersytet Jagielloński, Wydział Chemii

    Call: SONATA BIS 11, Panel: NZ7

  4. 4. Development of novel bimodal PET/MRI probes targeting PD-L1.

    Principal investigator: Anna Izabela Kastelik-Hryniewiecka

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

    Call: PRELUDIUM 21, Panel: NZ5

  5. 5. Investigation on PD-L1 biology for precise shaping of anticancer adoptive therapies

    Principal investigator: dr Agnieszka Graczyk-Jarzynka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

    Call: SONATA 15, Panel: NZ6

  6. 6. Evaluation of the anticancer efficacy of a new chimeric antigen receptor targeting PD-L1 molecule

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

    Call: OPUS 12, Panel: NZ6

  7. 7. Molecular mechanisms linking BRAF mutations and the expression of immunoregulatory molecules, galectin-1 and PD-L1 in me…

    Principal investigator: Maja Magdalena Wasylecka-Juszczyńska

    Instytut Hematologii i Transfuzjologii

    Call: PRELUDIUM 8, Panel: NZ5

  8. 8. Small-molecule inhibitors for characterization of the interaction between extracellular domains of Programmed Cell Death…

    Principal investigator: prof. Tadeusz Andrzej Holak

    Uniwersytet Jagielloński, Wydział Chemii

    Call: MAESTRO 9, Panel: ST5

  9. 9. Synthesis and evaluation of PD-L1 inhibitors based on mixed mode scaffolds containing amino acid derivatives, short pept…

    Principal investigator: dr Ewa Maria Surmiak

    Uniwersytet Jagielloński, Wydział Chemii

    Call: SONATA 16, Panel: ST4

  10. 10. Synthesis and Struktural Characterization of Small-Molecule Probes for the Programmed Death 1/ Programmed Death Ligand 1…

    Principal investigator: Katarzyna Agnieszka Guzik

    Uniwersytet Jagielloński, Wydział Chemii

    Call: PRELUDIUM 10, Panel: ST5

  11. 11. Photodynamic therapy combined with PD-1/PD-L1 blockade immunotherapy: new possibilities for the treatment of immunogenic…

    Principal investigator: dr hab. Janusz Marcin Dąbrowski

    Uniwersytet Jagielloński, Wydział Chemii

    Call: OPUS 19, Panel: NZ7

  12. 12. Structure optimization of the PD-1/PD-L1 inhibitors based on the terphenyl scaffold

    Principal investigator: dr Damian Muszak

    Uniwersytet Jagielloński, Wydział Chemii

    Call: PRELUDIUM 19, Panel: ST4

  13. 13. The role of the immune checkpoints in the pathomechanism of depressive disorders.

    Principal investigator: prof. Marta Wanda Kubera

    Instytut Farmakologii PAN

    Call: OPUS 22, Panel: NZ6

  14. 14. Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces…

    Principal investigator: prof. Tadeusz Holak

    Uniwersytet Gdański

    Call: OPUS 27, Panel: NZ7

  15. 15. Impact of the CDK4/6 targeted degradation by PROTACs on immune checkpoint signaling in cancer

    Principal investigator: dr Katarzyna Magiera-Mularz

    Uniwersytet Jagielloński, Wydział Chemii

    Call: OPUS 22, Panel: NZ7

Graphic design and implementation: Jakub Piotrowski