Projects funded by the NCN


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131 projects found matching your search criteria :

  1. The role of CXXC5 in the epigenetic profile of Hodgkin lymphoma

    Call: PRELUDIUM 24 , Panel: NZ2

    Principal investigator: Daniel Sikora

    Instytut Genetyki Człowieka PAN

  2. The role of clozapine in moderating the biological effects of miR-181b-5p and miR-34a-5p in the context of schizophrenia...

    Call: PRELUDIUM 24 , Panel: NZ5

    Principal investigator: Marek Mateusz Kotas

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  3. Mechanisms of programmed degradation of meiotic non-coding RNAs

    Call: OPUS 29 , Panel: NZ2

    Principal investigator: dr Jacek Krzysztof Nowak

    Instytut Biochemii i Biofizyki PAN

  4. Identifying changes in Purkinje cell chromatin dynamics as novel drivers of neuronal vulnerability in spinocerebellar at...

    Call: OPUS 29 , Panel: NZ2

    Principal investigator: dr Paweł Michał Świtoński

    Instytut Chemii Bioorganicznej PAN

  5. The role of DNA methylation in therapy that increases CFTR channel activity in cystic fibrosis

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Beata Maria Narożna

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  6. The role of EZH2 activity in the development of resistance to targeted therapy in melanoma

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr Michał Jerzy Woźniak

    Uniwersytet Medyczny w Łodzi

  7. Role of Histone Deacetylase 9 in B cell Non-Hodgkin's Lymphoma

    Call: OPUS 28 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Łukasz Szymański

    Instytut Genetyki i Hodowli Zwierząt PAN

  8. Revealing the component of epigenetic ageing in monocarpic plant leaves

    Call: SONATA 20 , Panel: NZ9

    Principal investigator: dr Magda Dominika Grabsztunowicz

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  9. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Leszczyńska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  10. N6-methyladenine metabolism - potential relationships with the development of hematological malignancies.

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Marta Starczak

    Uniwersytet Mikołaja Kopernika

  11. From methylation to malformation: the role of DNA methylation in the pathogenesis of Klippel-Feil syndrome

    Call: PRELUDIUM 23 , Panel: NZ5

    Principal investigator: Anna Szoszkiewicz

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  12. Impact of vitamin D on the epigenetic programming of CD34+ hematopoietic progenitor cells derived from human cord blood

    Call: OPUS 27 , Panel: NZ2

    Principal investigator: prof. Carsten Johannes Carlberg

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  13. Role of chromatin loops in transcription attenuation and termination

    Call: PRELUDIUM BIS 5 , Panel: NZ2

    Principal investigator: dr hab. Michał Ryszard Gdula

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  14. Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identificati...

    Call: JPND Call 2023 , Panel: NZ5

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  15. Biomaterials inducing DNA demethylation as tools for future neuron regeneration therapies

    Call: OPUS 25 , Panel: ST8

    Principal investigator: dr hab. Katarzyna Nawrotek

    Politechnika Warszawska

  16. Elucidating molecular mechanisms of the crosstalk between the muscle and the brain during physical activity in obesity

    Call: OPUS 25 , Panel: NZ9

    Principal investigator: prof. Joanna Helena Śliwowska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  17. Investigating the mechanisms of epigenetic memory at the example of the responsiveness of human immune cells to vitamin ...

    Call: OPUS 25 , Panel: NZ9

    Principal investigator: prof. Carsten Johannes Carlberg

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  18. The role of genome architecture and related chromatin modifications in innate immune transcriptional memory of antigen p...

    Call: Polskie Powroty NAWA 2022 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk - Imol

  19. Effect of embryonic signals on methylome of the porcine endometrium as a novel mechanism contributing to pregnancy estab...

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: prof. Agnieszka Wacławik

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  20. The impact of early life environment and (epi)genetics on animal cognition using a neuroepigenetic approach

    Call: PRELUDIUM BIS 4 , Panel: NZ8

    Principal investigator: dr hab. Irene Camerlink

    Instytut Genetyki i Hodowli Zwierząt PAN

  21. The discovery of multifactorial regulation at epigenetic memory of active gene expression state

    Call: SONATA 18 , Panel: NZ2

    Principal investigator: dr Paweł Sławomir Mikulski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  22. Mechanisms for Establishment of Transcriptional Memory

    Call: SONATA 18 , Panel: NZ1

    Principal investigator: dr Wojciech Siwek

    Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

  23. Decoding "metabolic memory" - how do glycemic control and variability affect epigenetic changes in young people with typ...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Wojciech Maksymilian Fendler

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  24. Impact of lipid metabolism on histone acetylation during mouse embryo development.

    Call: PRELUDIUM BIS 4 , Panel: NZ3

    Principal investigator: dr Domenico Iuso

    Instytut Genetyki i Hodowli Zwierząt PAN

  25. Molecular Mechanisms of Dietary Intervention on Neurodegeneration

    Call: JPND Call 2022 , Panel: NZ2

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  26. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  27. N6-methyladenosine (m6A) RNA modification as a putative metabolic switch between cell survival and cell death in induced...

    Call: PRELUDIUM 21 , Panel: NZ9

    Principal investigator: Elżbieta Marta Rudy

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  28. Transgenerational inheritance of Liver Disease in mouse offspring conceived by Assisted Reproduction Technologies.

    Call: SONATINA 6 , Panel: NZ4

    Principal investigator: dr Maria Florencia Heber

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  29. The role of histone-modifying enzymes in the epigenetics and pathogenesis of periodontitis.

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Aleksander M Grabiec

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  30. Structure-guided design of histone demethylase inhibitors for cancer therapy.

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Piotr Henryk Małecki

    Instytut Chemii Bioorganicznej PAN

  31. Epigenetic traces of anhydrobiosis: a study of DNA and protein modifications through tardigrade generations

    Call: PRELUDIUM BIS 3 , Panel: NZ4

    Principal investigator: dr hab. Robert Nawrot

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  32. Mechanisms of early embryo development impairment in hyperhomocysteinemia

    Call: OPUS 22 , Panel: NZ3

    Principal investigator: dr Joanna Maria Suszyńska-Zajczyk

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i i Biotechnologii

  33. Epigenetic regulation of estrogen receptor beta driven response in colon cancer.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Agnieszka Anna Rawłuszko-Wieczorek

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  34. Epigenetic regulation of exophers biogenesis

    Call: SONATA BIS 11 , Panel: NZ3

    Principal investigator: dr Michał Radosław Turek

    Instytut Biochemii i Biofizyki PAN

  35. The role of hypoxia-sensitive miRNA181a, miRNA199a, and SIRT1 in diabetes mellitus development in obstructive sleep apne...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Filip Franciszek Karuga

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  36. The genome-wide DNA methylation pattern alterations in the peripheral whole blood cells' in Graves' disease patients and...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Mikołaj Artur Radziszewski

    Warszawski Uniwersytet Medyczny

  37. Functional divergence of Flowering Locus T gene duplicates in photoperiod and vernalization control of flowering inducti...

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr hab. Michał Piotr Książkiewicz

    Instytut Genetyki Roślin PAN

  38. The effect of extremely low-frequency electromagnetic field (ELF-EMF) radiation on epigenetic regulation of gene express...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Paweł Józef Wydorski

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  39. Genetic and epigenetic fundamentals of cerebral vasospasm after aneurysmal subarachnoid hemorrhage

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: Tomasz Klepinowski

    Pomorski Uniwersytet Medyczny w Szczecinie

  40. MicroEpiQ: contact with adult as a major factor in microbiome-associated epigenetic modifications in Japanese quail (Cot...

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr hab. Anna Sławińska

    Uniwersytet Mikołaja Kopernika

  41. Polystyrene nanoparticles and their epigenetic and genotoxic properties in human peripheral blood mononuclear cells

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Kinga Malinowska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  42. Relevance of epigenetic regulation of the FKBP5 gene in moderating the association between psychosocial stress and psych...

    Call: OPUS 21 , Panel: HS6

    Principal investigator: dr hab. Błażej Andrzej Misiak

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

  43. Uracil in DNA and aberrant DNA methylation/hydroxymethylation as a new biomarkers of multiple myeloma development? A sea...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: prof. Ryszard Oliński

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  44. The role of 5-hydroxymethyluracil in chronic lymphocytic leukemia development

    Call: PRELUDIUM BIS 2 , Panel: NZ5

    Principal investigator: dr hab. Daniel Stefan Gackowski

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

  45. Mechanisms of modification breast cancer risk by environmentally induced epigenetic changes.

    Call: PRELUDIUM BIS 2 , Panel: NZ2

    Principal investigator: dr hab. Tomasz Kazimierz Wojdacz

    Pomorski Uniwersytet Medyczny w Szczecinie

  46. The role of 3D genome folding in the establishment of keratinocyte-specific promoter-enhancer network.

    Call: OPUS 19 , Panel: NZ3

    Principal investigator: dr hab. Michal Ryszard Gdula

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  47. The cell reprogramming processes: epigenetic and proteomic analyses of the cell fate in common and Tartary buckwheat

    Call: OPUS 19 , Panel: NZ9

    Principal investigator: dr Alexander Betekhtin

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  48. Mutations of cis-regulatory elements as potential mechanism leading to chromatin inaccessibility and gene silencing in c...

    Call: PRELUDIUM 19 , Panel: NZ2

    Principal investigator: Adam Ustaszewski

    Instytut Genetyki Człowieka PAN

  49. Application of small compounds in the epigenetic therapy of malignant brain gliomas

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Mirosława Zofia Naskręt-Barciszewska

    Instytut Chemii Bioorganicznej PAN

  50. Epigenetic immunomodulation dependent on elements of the microbiome. Model of direct and indirect interactions of Th17 a...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr hab. Marcin Marek Ratajewski

    Instytut Biologii Medycznej PAN