Projects funded by the NCN


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114 projects found matching your search criteria :

  1. Game of Tails: Understanding the role of 3'-end processing of long noncoding RNAs during zebrafish development

    Call: PRELUDIUM 21 , Panel: NZ2

    Principal investigator: Monika Kwiatkowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  2. Ultrasensitive profiling of mutations driving tumorigenesis in hereditary syndromes associated with tumor suppressor gen...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr Katarzyna Klonowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  3. RAN translation at CAG repeats in spinocerebellar ataxia type 3

    Call: SONATA 10 , Panel: NZ5

    Principal investigator: dr Magdalena Jazurek-Ciesiołka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  4. Histidine Biosynthetic Pathway in Plants: Structural and Functional Studies as a Framework for the Design of Inhibitors ...

    Call: SONATA 14 , Panel: NZ1

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  5. Deciphering the molecular causes and consequences of circular RNAs elevated expression levels in myotonic dystrophy type...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  6. Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular bi...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Dagmara Baraniak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  7. Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites.

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  8. Antibiotic resistance genes and integrons as indicators of biotic pollution and resistance load of Arctic ecosystems

    Call: SONATINA 4 , Panel: NZ9

    Principal investigator: dr Nicoletta Makowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  9. In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

    Call: OPUS 10 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  10. The role of membrane transporters in the cytokinin signaling upon Legume- Rhizobia Symbiosis

    Call: OPUS 10 , Panel: NZ9

    Principal investigator: dr hab. Michał Jasiński

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  11. Identification of CAG repeat-binding proteins and imaging RNA-protein interactions in cells

    Call: OPUS 10 , Panel: NZ2

    Principal investigator: dr Adam Ciesiołka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  12. Bifunctional antisense oligonucleotides - optimization of alternative splicing regulation in cancer cell lines

    Call: SONATA 11 , Panel: NZ5

    Principal investigator: dr Jolanta Lisowiec-Wąchnicka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  13. Modified siRNAs, ribozymes and CRISPR/Cas system as strategies for influenza A virus inhibition. Application and compari...

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: dr Julita Piasecka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  14. N-Oxide phosphobetaines in new synthetic strategies for P-modified phosphates and polyphospates of natural biomolecules ...

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Magdalena Materna

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  15. Function of secondary structure of influenza A virus vRNA in ribonucleoprotein complex during viral life cycle

    Call: SONATINA 1 , Panel: NZ1

    Principal investigator: dr Elżbieta Lenartowicz

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  16. Development of methodology aiming at stabilisation of RNA in a hairpin form for crystallographic studies

    Call: SONATA BIS 7 , Panel: NZ1

    Principal investigator: dr hab. Agnieszka Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  17. The characteristic of the regulatory RNAs landscape in glioblastoma multiforme (GBM). Circular RNAs and micro RNA-like m...

    Call: SONATA BIS 7 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Rolle

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  18. Mechanisms of human gene expression regulation by uridilation

    Call: SONATA 13 , Panel: NZ1

    Principal investigator: dr hab. Zbigniew Warkocki

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  19. Caged bioluminogenic substrates for a selective molecular imaging of biochemical parameters in cancer

    Call: SONATA 13 , Panel: NZ1

    Principal investigator: dr Jacek Kolanowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  20. Lanthanide binding oligonucleotides (LBOs) as paramagnetic tags for NMR spectroscopy of nucleic acids

    Call: OPUS 19 , Panel: ST4

    Principal investigator: dr Witold Andrałojć

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  21. Identification of cancer-driver mutations in non-coding parts of protein-coding genes and long non-coding RNA genes

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: prof. Piotr Kozłowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  22. Function and dysfunction of repeated tracts in non-coding and protein-coding transcripts

    Call: OPUS 21 , Panel: NZ3

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  23. Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Weronika Kotkowiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  24. Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  25. Exploring Ty3 genomic RNA structure during retrotransposition in yeast

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: Angelika Andrzejewska-Romanowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  26. Searching for novel mechanisms of gene expression regulation, independent from RNAi pathway - short RNAs derived from sn...

    Call: SONATA 7 , Panel: NZ1

    Principal investigator: dr Kamilla Bąkowska-Żywicka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  27. Kinetin riboside and its derivatives-analysis of apoptotic properties and mechanism of action in brain tumor cells

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Eliza Wyszko

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  28. Inhibition of S-adenosyl-L-homocysteine hydrolase from Pseudomonas aeruginosa by targeting the enzyme dynamics

    Call: SONATA BIS 8 , Panel: NZ1

    Principal investigator: dr hab. Krzysztof Brzeziński

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  29. Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficienc...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  30. Thermodynamic parameters and rules towards the determination of RNA folding in in vivo-like conditions. RNA folding pred...

    Call: OPUS 17 , Panel: ST4

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  31. Allele-selective therapy for polyglutamine diseases with the use of RNA interference technology

    Call: PRELUDIUM BIS 1 , Panel: NZ1

    Principal investigator: dr hab. Marta Olejniczak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  32. Description of the key mechanisms of coordination and prioritization of barley's response to simultaneous biotic and abi...

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: dr Anna Piasecka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  33. Microscopic identification of proteins involved in DNA repair of CAG repeats regions

    Call: PRELUDIUM 21 , Panel: NZ3

    Principal investigator: Mateusz Nowaczyk

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  34. Multiomic characterization of neurogenerative processes in Zebrin-II positive and Zebrin-II negative Purkinje cells

    Call: PRELUDIUM 22 , Panel: NZ3

    Principal investigator: Grażyna Adamek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  35. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  36. Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  37. RNA structures and interactions with Gag protein that specify Ty1 RNA functions during retrotransposon replication

    Call: SONATA BIS 6 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Pachulska-Wieczorek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  38. Unknown areas of activity of human ribonuclease Dicer

    Call: SONATA BIS 6 , Panel: NZ1

    Principal investigator: dr hab. Anna Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  39. Designing a new method for direct identification and absolute quantification of premature transcription termination even...

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: dr Piotr Machtel

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  40. Copy number polymorphism of microRNA genes in Arabidopsis thaliana accessions and its impact on the post-transcriptional...

    Call: PRELUDIUM 13 , Panel: NZ2

    Principal investigator: dr Anna Samelak-Czajka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  41. Cotranscriptional folding of influenza virus RNA in MDCK cells in presence of antisense oligonucleotides. A new method f...

    Call: OPUS 13 , Panel: NZ1

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  42. Functional crostallk between circRNAs and extracellular matrix (ECM) - the importance for glioblastoma stem cells (GSC) ...

    Call: OPUS 13 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Rolle

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  43. Identification of biomolecules released by colorectal cancer cells and detected in serum or/and exosomes

    Call: SONATA 13 , Panel: NZ2

    Principal investigator: dr hab. Anna Wojakowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  44. Changes in the ribosomal protein composition and in the ribosome-associated small noncoding RNAs in Saccharomyces cerevi...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: dr hab. Kamilla Grzywacz

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  45. The study of chitinolytic enzymes, aiming at constructing an artificial chitinosome.

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: prof. Wojciech Rypniewski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  46. Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: dr Paweł Zmora

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  47. Comprehensive analysis of the Schmidtea mediterranea transcriptome – identification of non-coding RNAs involved in cell ...

    Call: OPUS 18 , Panel: NZ2

    Principal investigator: dr hab. Paulina Jackowiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  48. Anticoagulant and antiproliferative properties of novel thrombin binding aptamer analogues

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: Weronika Kotkowiak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  49. The role of protein factors that bind to the 5' non-coding region of human p53 mRNA in regulation of p53 expression at t...

    Call: OPUS 11 , Panel: NZ1

    Principal investigator: prof. Jerzy Ciesiołka

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  50. Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer

    Call: SONATA 11 , Panel: NZ3

    Principal investigator: dr Patrick Perrigue

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk