Projects funded by the NCN

New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in...

Call: OPUS 5 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an...

Call: SONATA BIS 1 , Panel: ST5

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Identification and therapeutic targeting of the mRNA splicing alteration mechanisms driven by gain-of-function TP53 muta...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Magdalena Oroń

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Mammalian cell delivery of stable therapeutic mRNA packaged inside virus-like particles.

Call: OPUS 17 , Panel: NZ6

Principal investigator: prof. Bogusław Szewczyk

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

mRNA 5' end methylation status: towards deeper understanding of biological role and identification of synthetic mimics

Call: OPUS 17 , Panel: ST4

Principal investigator: dr hab. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of...

Call: OPUS 17 , Panel: NZ1

Principal investigator: prof. Edward Darżynkiewicz

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Gold and silver nanoparticles as carriers for delivery of 5' end mRNA cap analogues with potential therapeutical applica...

Call: OPUS 16 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Investigating the biological role of 5' nucleotidases cN-IIIA and cN-IIIB in mRNA degradation and their terapeutic signi...

Call: SONATINA 1 , Panel: NZ1

Principal investigator: dr Dorota Kubacka

Uniwersytet Warszawski, Wydział Fizyki

Chemically modified mRNA for studies on cellular processes and therapeutic applications

Call: OPUS 11 , Panel: ST5

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego