Projects funded by the NCN

Development and study of peptide inhibitors of membrane fusion in flaviviruses, based on the STEM region of the tick-bor...

Call: PRELUDIUM 24 , Panel: NZ6

Principal investigator: Krzysztof Polaczek

Uniwersytet Gdański

Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Synthesis and evaluation of PD-L1 inhibitors based on mixed mode scaffolds containing amino acid derivatives, short pept...

Call: SONATA 16 , Panel: ST4

Principal investigator: dr Ewa Maria Surmiak

Uniwersytet Jagielloński, Wydział Chemii

Application of N-(2-thioethyl)glycine analogues in orthogonal cleavage of peptides from solid support

Call: PRELUDIUM 18 , Panel: ST4

Principal investigator: Magdalena Elżbieta Wierzbicka

Uniwersytet Wrocławski, Wydział Chemii

Novel analogs of human cathelicidin (LL-37) with enhanced resistant to enzymatic degradation. Design chemical synthesis ...

Call: PRELUDIUM BIS 1 , Panel: ST4

Principal investigator: prof. Adam Jerzy Lesner

Uniwersytet Gdański, Wydział Chemii

Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

New class of nucelus penetrating peptides. Design, synthesis and mechanism of action

Call: OPUS 14 , Panel: ST5

Principal investigator: dr hab. Magdalena Wysocka

Uniwersytet Gdański, Wydział Chemii

Do copper(I) complexes with conjugates of phosphine-peptide carriers can cause selective cancer cells death? Synthesis, ...

Call: SONATA 12 , Panel: ST5

Principal investigator: dr Urszula Katarzyna Komarnicka

Uniwersytet Wrocławski, Wydział Chemii

The research on the use of novel analogues of endogenous antimicrobial peptides in therapy of staphylococcal skin infect...

Call: OPUS 12 , Panel: NZ7

Principal investigator: prof. Wojciech Kamysz

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Design and chemical synthesis of peptide-based conjugates with antimicrobial activity - a promising approach to improve ...

Call: OPUS 11 , Panel: ST5

Principal investigator: prof. Krzysztof Rolka

Uniwersytet Gdański, Wydział Chemii

Dehydropeptides as substrates for synthesis of building blocks for construction artzymes

Call: OPUS 11 , Panel: ST5

Principal investigator: prof. Paweł Kazimierz Kafarski

Politechnika Wrocławska

Synthesis, physicochemical and biological properties of thymosin beta4 - boron cluster conjugates. New strategy of impro...

Call: PRELUDIUM 10 , Panel: NZ7

Principal investigator: Krzysztof Konrad Fink

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple recept...

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Anna Ewa Janecka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Synthesis and tandem mass spectrometry examination of new ionization tags based on thiazolidinecarboxylic acid and oxazo...

Call: PRELUDIUM 8 , Panel: ST5

Principal investigator: Bartosz Wojciech Setner

Uniwersytet Wrocławski, Wydział Chemii

Can Fusobacterium nucleatum adhesion proteins increase prooxidative activity of iron and copper ions?

Call: OPUS 7 , Panel: ST5

Principal investigator: dr Kamila Kamila Stokowa-Sołtys

Uniwersytet Wrocławski, Wydział Chemii

Design, chemical synthesis and biological activity of inhibitors of matriptase-2.

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: Agata Elżbieta Gitlin-Domagalska

Uniwersytet Gdański, Wydział Chemii

Synthesis and structural study of modified porphyrinoids

Call: PRELUDIUM 6 , Panel: ST5

Principal investigator: Justyna Śniechowska

Centrum Badań Molekularnych i Makromolekularnych PAN

A development of a method of micro-scale synthesis of peptides labelled with stable isotopes for quantitative proteomics

Call: PRELUDIUM 6 , Panel: ST4

Principal investigator: Maciej Paweł Modzel

Uniwersytet Wrocławski, Wydział Chemii

Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

Call: OPUS 6 , Panel: ST5

Principal investigator: dr hab. Marzena Jankowska-Anyszka

Uniwersytet Warszawski, Wydział Chemii

Synthesis, physico-chemical and biological studies on macromolecular carriers of antimicrobial peptides

Call: PRELUDIUM 6 , Panel: NZ7

Principal investigator: Urszula Helena Piotrowska

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Synthesis and pharmacological characterization of novel cyclic opioid peptide analogs incorporating fluoro amino acids.

Call: PRELUDIUM 5 , Panel: NZ7

Principal investigator: dr Justyna Piekielna-Ciesielska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Synthesis and fragmentation of peptides conjugated with betaine derivatives - a search for isobaric markers for quantita...

Call: OPUS 5 , Panel: ST4

Principal investigator: prof. Zbigniew Szewczuk

Uniwersytet Wrocławski, Wydział Chemii

Morita-Baylis-Hillman adducts as substrates in the synthesis of biologically active organophosphorus compounds

Call: OPUS 5 , Panel: ST5

Principal investigator: dr hab. Artur Jacek Mucha

Politechnika Wrocławska, Wydział Chemiczny

Synthetic cysteine peptides as molecular layers for studies of interactions between copper ions and beta-amyloid

Call: SONATA 4 , Panel: ST4

Principal investigator: dr Urszula Elżbieta Wawrzyniak

Politechnika Warszawska, Wydział Chemiczny

Design, chemical synthesis and enzymatic evaluation of peptidic substrates and inhibitors of cathepsin C

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: dr Monika Katarzyna Łęgowska

Uniwersytet Gdański, Wydział Chemii

Fluorescent substrates of neutrophil proteinases: design, chemical synthesis , selection by the combinatorial chemistry ...

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: dr Jadwiga Danuta Popow - Stellmaszyk

Uniwersytet Gdański, Wydział Chemii

Synthesis and biological studies of conjugates formed by peptide dendrimers and natural polyphenols and their analogs

Call: OPUS 4 , Panel: ST5

Principal investigator: prof. Zofia Lipkowska

Instytut Chemii Organicznej Polska Akademia Nauk

Quaternary ammonium salts of cryptando-peptidic conjugates. Synthesis and chemical properties.

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: dr Remigiusz Marcin Bąchor

Uniwersytet Wrocławski, Wydział Chemii

The impact of synthetic modifications of the histidine side chain on coordination properties of analogues of the N-termi...

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: dr Izabela Anna Zawisza

Instytut Biochemii i Biofizyki PAN

Identification of amino acid residues located in positions P7 and P8 of model inhibitor of proprotein convertases that d...

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: Izabela Małuch

Uniwersytet Gdański, Wydział Chemii

Synthesis of deltorphin I and dermorphin analogues modified with alfa-alkyl-beta-azido(amino)alanine in postion 2 or 3.

Call: PRELUDIUM 2 , Panel: ST5

Principal investigator: Anika Marta Lasota

Politechnika Łódzka, Politechnika Łódzka, Wydział Chemiczny,