Projects funded by the NCN

Hepatic neoplasia modifications induced by reprograming of the monocyte/macrophage system in rats and humans.

Call: OPUS 8 , Panel: NZ5

Principal investigator: dr Marta Wójcik

Uniwersytet Przyrodniczy w Lublinie, Wydział Medycyny Weterynaryjnej

New mechanisms of cellular reprogramming: role of TLR3 and RIG-1 activation and downstream anti-inflammatory response to...

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: dr Jacek Stępniewski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Reprogramming of somatic cells in the environment of early mouse embryo, characteristics of reprogrammed cells and deriv...

Call: PRELUDIUM 3 , Panel: NZ3

Principal investigator: dr Krystyna Żyżyńska-Galeńska

Instytut Genetyki i Hodowli Zwierząt PAN

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

FATE-IDR: The role of intrinsically disordered protein domains in cell fate determination

Call: Polskie Powroty NAWA 2021 , Panel: NZ1

Principal investigator: dr Adam Stanisław Kłosin

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Targeting of metabolic and transcriptomic cross-talk between leukemic cells and macrophages as a therapeutic strategy in...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr Baran Natalia

Instytut Hematologii i Transfuzjologii

Identification of molecular mechanism underlying the phenotype development of Emery-Dreifuss muscular dystrophy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Katarzyna Piekarowicz

Uniwersytet Wrocławski, Wydział Biotechnologii

Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Carlo Vascotto

Instytut Hematologii i Transfuzjologii

Identification of novel disease modifiers in Huntington's disease: neuro-glia interactions in the patient-derived multid...

Call: SONATA BIS 11 , Panel: NZ3

Principal investigator: dr Agnieszka Krzyżosiak

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Metabolic reprogramming in age-dependent endothelial dysfunction and vascular stiffness; novel mechanism of 'inflamm-age...

Call: MAESTRO 13 , Panel: NZ4

Principal investigator: prof. Stefan Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Building a genomic atlas of human inner ear malformations: focus on novel genes and functional non-coding regions

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr hab. Monika Ołdak

Instytut Fizjologii i Patologii Słuchu

Epigenetic Reprograming and All-trans-Retinoic Acid in Therapy of Myelodysplastic Syndromes

Call: OPUS 21 , Panel: NZ5

Principal investigator: prof. Artur Zelent

Instytut Genetyki i Biotechnologii Zwierząt Polskiej Akademii Nauk

Modulation of ATP production using glycolysis inhibitors in cancer cells monitored by novel biosensing systems based on ...

Call: PRELUDIUM 19 , Panel: ST4

Principal investigator: Katarzyna Ratajczak

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

The cell reprogramming processes: epigenetic and proteomic analyses of the cell fate in common and Tartary buckwheat

Call: OPUS 19 , Panel: NZ9

Principal investigator: dr Alexander Betekhtin

Uniwersytet Śląski w Katowicach, Wydział Nauk Przyrodniczych

Development of an innovative method of preparing iPS cells for gene-cell therapy of hereditary diseases based on the Ost...

Call: PRELUDIUM 19 , Panel: NZ2

Principal investigator: Agnieszka Fus-Kujawa

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Protaminization of somatic cells nuclei as a model for nuclear reprogramming in somatic cell nuclear transfer.

Call: OPUS 18 , Panel: NZ3

Principal investigator: dr hab. Marta Czernik

Instytut Genetyki i Hodowli Zwierząt Polskiej Akademii Nauk

Modified tumor-derived exosomes as novel nanocarriers of anti-tumor molecules for the reprogramming of tumor microenviro...

Call: SONATA BIS 8 , Panel: NZ5

Principal investigator: dr hab. Joanna Rossowska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Development of alternative and effecive strategies for induction full nuclear reprogramming of somatic nuclei introduced...

Call: PRELUDIUM 1 , Panel: NZ3

Principal investigator: Magdalena Kotlarska

Instytut Genetyki i Hodowli Zwierząt PAN

Reprograming of leaves senescence by polyamines - new perspectives to enhance crop plants stress tolerance

Call: PRELUDIUM 14 , Panel: NZ9

Principal investigator: dr Ewelina Paluch-Lubawa

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The influence of mitochondria-derived hydrogen sulfide (H2S) on the reprogramming of macrophages in atherosclerosis and ...

Call: SONATA 13 , Panel: NZ4

Principal investigator: dr Aneta Stachowicz

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

Reprogramming antitumor innate immunity in gliomas with osteopontin/Spp1 interfering peptides and nanovehicles-delivered...

Call: OPUS 13 , Panel: NZ3

Principal investigator: dr Aleksandra Ellert-Miklaszewska

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Cytoplasmatic roadblocks in cell fate reprogramming: from players to molecular mechanisms

Call: OPUS 10 , Panel: NZ3

Principal investigator: dr hab. Rafał Ciosk

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk