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Information on the principal investigator and host institution

Information of the project and the call

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Hepatic neoplasia modifications induced by reprograming of the monocyte/macrophage system in rats and humans.

2014/15/B/NZ5/01587

Keywords:

hepatocellular carcinoma M1 macrophages training immunity oval cells

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_4: Pathogenesis of animal diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Przyrodniczy w Lublinie, Wydział Medycyny Weterynaryjnej

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marta Wójcik 

Number of co-investigators in the project: 6

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 350 000 PLN

Project start date (Y-m-d): 2015-09-02

Project end date (Y-m-d): 2019-01-01

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (4)
  1. Expression of receptor interacting protein 1 and receptor interacting protein 3 oval cells in rat model of hepatocarcinogenesis
    Authors:
    Wójcik Marta, Bobowic Ryszard, Lisiecka Urszula, Śmiech Anna
    Academic press:
    Experimental and Therapeutic medicine (rok: 2018, tom: 15, strony: 4448-4456), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/etm.2018.5988 - link to the publication
  2. In Vitro Proinflamtory Polarization of Macrophages Isolated from Hepatocrcinogenic Stage in Humans and Rats
    Authors:
    Marta Wójcik, Joanna Wessely-Szponder, Halina Cichoż-Lach, Krzysztof Celiński, Ryszard Bobowiec
    Academic press:
    In Vivo (rok: 2016, tom: 30, strony: 853-862), Wydawca: International Institute of Anticancer Research
    Status:
    Published
    DOI:
    10.21873/invivo.11005 - link to the publication
  3. Influence of proinflammatory macrophages (M-1) on proliferative activity and PPAR -γ expression of neoplastic rat hepatocytes in vitro
    Authors:
    Wójcik Marta, Kosior-Korzecka Urszula, Plewik Michał, Bobowiec Ryszard
    Academic press:
    Medycyna Weterynaryjna (rok: 2019, tom: 75, strony: 572-576), Wydawca: Polskie Towarzystwo Nauk Weterynaryjnych
    Status:
    Published
    DOI:
    10.21521/mw.6220 - link to the publication
  1. Activity of heme oxygenase and thiobarbituric acid-reactive substances (TBRAS)in neoplastic hepatocytes co-cultured with proinflamatory macrophages M1 in 3D Quasi-Vivo System.
    Authors:
    Wójcik M., Bobowiec R., Kosior-Korzecka U., Celiński K.
    Conference:
    27th Congress of the Polish Physiological Society (rok: 2017, ), Wydawca: Polish Physiological Society
    Data:
    konferencja 21-22 September
    Status:
    Published
  2. Activity of Neoplastic Rat Hepatocytes Co-Cultured with Proinflamatory Macrophages (M-1) In Vitro.
    Authors:
    Marta Wójcik, Joanna Wessely-Szponder, Ryszard Bobowiec, Urszula Kosior-Korzecka
    Conference:
    XV Kongres Polskiego Towarzystwa Nauk Weterynaryjnych (rok: 2016, ), Wydawca: Wydawnictwo Morpol
    Data:
    konferencja 22-24.09.
    Status:
    Published
  3. Gene expression of Cycline E2 and kinases MAPK in rat neoplastic hepatocytes exposed on proinflammatory macrophages M1 in vitro
    Authors:
    Marta Wójcik, Urszula Kosior-Korzecka
    Conference:
    XXI Zjazd Polskiego Towarzystwa Patologów (rok: 2019, ), Wydawca: Polish Journal of Pathology
    Data:
    konferencja 26-28 września
    Status:
    Published
  4. Apoptotic and necroptotic potential in progenitor cells of hepatocellular carcinoma.
    Authors:
    Bobowiec R., Wójcik M., Lisiecka U
    Conference:
    27th Congress of the Polish Physiological Society (rok: 2017, ), Wydawca: Polish Physiological Society
    Data:
    konferencja 21-22 September
    Status:
    Published

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