Projects funded by the NCN

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43 projects found matching your search criteria :

  1. Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Małgorzata Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. Abeta 4-x peptides as copper binding molecules resistant to chelating drugs, promoting the formation of amyloid oligomer...

    Call: OPUS 8 , Panel: ST5

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki PAN

  3. Engineering disulfide bridges in human beta-defensin 3 for novel antibacterial and antifungal activities

    Call: SONATA 8 , Panel: ST5

    Principal investigator: dr Aleksandra Walewska

    Uniwersytet Gdański, Wydział Chemii

  4. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  5. Impact of opioid-neurotensin chimera (PK20) on inflammation in murine model of contact sensitivity reaction and non-atho...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kaczyńska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  6. Novel peptide inhibitors of dipeptidyl peptidase IV (DPP IV) as novel approach for diabetes type 2 and inflammatory bowe...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Maciej Sałaga

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  7. Synthesis, physico-chemical and biological studies on macromolecular carriers of antimicrobial peptides

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Urszula Piotrowska

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  8. Synthesis and pharmacological characterization of novel cyclic opioid peptide analogs incorporating fluoro amino acids.

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  9. Functionalization of photosensitizing compounds with antimicrobial peptides to enhance photoantimicrobial chemotherapy o...

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr Joanna Nakonieczna

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  10. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Detka

    Instytut Farmakologii PAN

  11. A novel strategy for construction of antifungal pro-drugs based on the cell-penetrating peptides

    Call: OPUS 3 , Panel: ST5

    Principal investigator: prof. Sławomir Milewski

    Politechnika Gdańska, Wydział Chemiczny

  12. Development and evaluation of a new type of wound healing stimulators based on binding loops of the PDGF and VEGF growth...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Przemysław Karpowicz

    Uniwersytet Gdański, Wydział Chemii

  13. Metallacarborane-peptide amphiphiles as a new strategy in the fight against multidrug-resistant Gram-negative bacteria

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Krzysztof Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  14. Macrocyclic peptides for targeting of membrane-anchored serine protease

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Paulina Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  15. Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Piotr Chyży

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  16. Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Izabela Siekierska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  17. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Piotrowska

    Warszawski Uniwersytet Medyczny

  18. Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Natalia Karska

    Uniwersytet Gdański, Wydział Chemii

  19. Anticancer drug candidates from Nostoc edaphicum CCNP1411 and Pseudanabaena galeata CCNP1313 (CYANOCRAB)

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: prof. Hanna Mazur-Marzec

    Uniwersytet Gdański, Wydział Oceanografii i Geografii

  20. Bionanoparticles with a molecular targeting device as a weapon for breast cancer

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  21. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Papaj

    Politechnika Śląska, Centrum Biotechnologii

  22. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Instytut Hematologii i Transfuzjologii

  23. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  24. Development of tools for the rational design of peptide therapeutics

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Sebastian Kmiecik

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  25. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  26. Studies over the dissociation of peptides in non-aqueous enviroments and the development of a universal counter-ion exch...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  27. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  28. Lipophilic Prodrug Charge Masking (LPCM) as a novel strategy to enhance oral bioavailability of charged active peptides....

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Agata Gitlin-Domagalska

    Uniwersytet Gdański, Wydział Chemii

  29. The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – foc...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Marta Zielińska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  30. Conjugates of metallacarboranes and short cationic peptides with antibacterial and anticancer activity.

    Call: SONATINA 3 , Panel: NZ7

    Principal investigator: dr Krzysztof Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  31. Effect of omega-3 fatty acids supplementation on exercise-induced myokines and other peptides in physically active men

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Maja Tomczyk

    Akademia Wychowania Fizycznego i Sportu im. Jędrzeja Śniadeckiego w Gdańsku, Wydział Wychowania Fizycznego

  32. Mesoporous and self-assembling molecular transporters as carriers of drugs and others low-molecular chemical species.

    Call: OPUS 16 , Panel: ST4

    Principal investigator: prof. Marek Potrzebowski

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  33. Development of macrocyclic peptide antagonists of the PD-1/PD-L1 pathway. Charcterization of simultaneous administration...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Katarzyna Magiera-Mularz

    Uniwersytet Jagielloński, Wydział Chemii

  34. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  35. Investigation of the effect of thiol group and urea bond on the peptidomimetics' affinity to receptors associated with a...

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: dr Anna Puszko

    Uniwersytet Warszawski, Wydział Chemii

  36. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. Directed Evolution of Peptides Able to Dissolve Crystals of Calcium Pyrophosphate Dihydrate- a factor causing Calcium Py...

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: Radosław Piast

    Uniwersytet Warszawski, Wydział Chemii

  38. Interaction of membrane-active peptides with model cell membrane and their role in a drug delivery system. Electrochemic...

    Call: OPUS 12 , Panel: ST4

    Principal investigator: dr Piotr Pięta

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  39. The research on the use of novel analogues of endogenous antimicrobial peptides in therapy of staphylococcal skin infect...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  40. Design and chemical synthesis of peptide-based conjugates with antimicrobial activity - a promising approach to improve ...

    Call: OPUS 11 , Panel: ST5

    Principal investigator: prof. Krzysztof Rolka

    Uniwersytet Gdański, Wydział Chemii

  41. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Barbara Malawska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  42. Synthesis, physicochemical and biological properties of thymosin beta4 - boron cluster conjugates. New strategy of impro...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Krzysztof Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  43. Ability of CRISPR/dCas9 system and cell-penetrating proteins as the aim of prevention against coronary artery restenosis...

    Call: SONATA 9 , Panel: NZ7

    Principal investigator: dr Maciej Gagat

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Lekarski

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