Projects funded by the NCN

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44 projects found matching your search criteria :

  1. Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. Abeta 4-x peptides as copper binding molecules resistant to chelating drugs, promoting the formation of amyloid oligomer...

    Call: OPUS 8 , Panel: ST5

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  3. Engineering disulfide bridges in human beta-defensin 3 for novel antibacterial and antifungal activities

    Call: SONATA 8 , Panel: ST5

    Principal investigator: dr Aleksandra Walewska

    Uniwersytet Gdański, Wydział Chemii

  4. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  5. Impact of opioid-neurotensin chimera (PK20) on inflammation in murine model of contact sensitivity reaction and non-atho...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kaczyńska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  6. Novel peptide inhibitors of dipeptidyl peptidase IV (DPP IV) as novel approach for diabetes type 2 and inflammatory bowe...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Maciej Stanisław Sałaga

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  7. Synthesis, physico-chemical and biological studies on macromolecular carriers of antimicrobial peptides

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Urszula Helena Piotrowska

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  8. Synthesis and pharmacological characterization of novel cyclic opioid peptide analogs incorporating fluoro amino acids.

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  9. Functionalization of photosensitizing compounds with antimicrobial peptides to enhance photoantimicrobial chemotherapy o...

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr Joanna Nakonieczna

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  10. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Stanisław Detka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. A novel strategy for construction of antifungal pro-drugs based on the cell-penetrating peptides

    Call: OPUS 3 , Panel: ST5

    Principal investigator: prof. Sławomir Piotr Milewski

    Politechnika Gdańska, Wydział Chemiczny

  12. The first antibody-drug conjugates for Alzheimer's disease therapy

    Call: SONATA BIS 14 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  13. Development and evaluation of a new type of wound healing stimulators based on binding loops of the PDGF and VEGF growth...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Przemysław Karpowicz

    Uniwersytet Gdański, Wydział Chemii

  14. Metallacarborane-peptide amphiphiles as a new strategy in the fight against multidrug-resistant Gram-negative bacteria

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Krzysztof Konrad Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  15. Macrocyclic peptides for targeting of membrane-anchored serine protease

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  16. Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Piotr Maciej Chyży

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  17. Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Izabela Siekierska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  18. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Helena Piotrowska

    Warszawski Uniwersytet Medyczny

  19. Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Natalia Anna Karska

    Uniwersytet Gdański, Wydział Chemii

  20. Anticancer drug candidates from Nostoc edaphicum CCNP1411 and Pseudanabaena galeata CCNP1313 (CYANOCRAB)

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: prof. Hanna Jurata Mazur-Marzec

    Uniwersytet Gdański, Wydział Biologii

  21. Bionanoparticles with a molecular targeting device as a weapon for breast cancer

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  22. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Joanna Papaj

    Politechnika Śląska, Centrum Biotechnologii

  23. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  24. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  25. Development of tools for the rational design of peptide therapeutics

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Sebastian Kmiecik

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  26. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  27. Studies over the dissociation of peptides in non-aqueous enviroments and the development of a universal counter-ion exch...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  28. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Marek Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  29. Lipophilic Prodrug Charge Masking (LPCM) as a novel strategy to enhance oral bioavailability of charged active peptides....

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Agata Elżbieta Gitlin-Domagalska

    Uniwersytet Gdański, Wydział Chemii

  30. The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – foc...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Marta Zielińska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  31. Conjugates of metallacarboranes and short cationic peptides with antibacterial and anticancer activity.

    Call: SONATINA 3 , Panel: NZ7

    Principal investigator: dr Krzysztof Konrad Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  32. Effect of omega-3 fatty acids supplementation on exercise-induced myokines and other peptides in physically active men

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Maja Zofia Tomczyk

    Akademia Wychowania Fizycznego i Sportu im. Jędrzeja Śniadeckiego w Gdańsku, Wydział Wychowania Fizycznego

  33. Mesoporous and self-assembling molecular transporters as carriers of drugs and others low-molecular chemical species.

    Call: OPUS 16 , Panel: ST4

    Principal investigator: prof. Marek Józef Potrzebowski

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  34. Development of macrocyclic peptide antagonists of the PD-1/PD-L1 pathway. Charcterization of simultaneous administration...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Katarzyna Magiera-Mularz

    Uniwersytet Jagielloński, Wydział Chemii

  35. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Elżbieta Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  36. Investigation of the effect of thiol group and urea bond on the peptidomimetics' affinity to receptors associated with a...

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: dr Anna Katarzyna Puszko

    Uniwersytet Warszawski, Wydział Chemii

  37. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  38. Directed Evolution of Peptides Able to Dissolve Crystals of Calcium Pyrophosphate Dihydrate- a factor causing Calcium Py...

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: Radosław Wojciech Piast

    Uniwersytet Warszawski, Wydział Chemii

  39. Interaction of membrane-active peptides with model cell membrane and their role in a drug delivery system. Electrochemic...

    Call: OPUS 12 , Panel: ST4

    Principal investigator: dr Piotr Rafał Pięta

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  40. The research on the use of novel analogues of endogenous antimicrobial peptides in therapy of staphylococcal skin infect...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  41. Design and chemical synthesis of peptide-based conjugates with antimicrobial activity - a promising approach to improve ...

    Call: OPUS 11 , Panel: ST5

    Principal investigator: prof. Krzysztof Rolka

    Uniwersytet Gdański, Wydział Chemii

  42. Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Barbara Antonina Malawska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  43. Synthesis, physicochemical and biological properties of thymosin beta4 - boron cluster conjugates. New strategy of impro...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Krzysztof Konrad Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  44. Ability of CRISPR/dCas9 system and cell-penetrating proteins as the aim of prevention against coronary artery restenosis...

    Call: SONATA 9 , Panel: NZ7

    Principal investigator: dr Maciej Gagat

    Uniwersytet Mikołaja Kopernika w Toruniu; Collegium Medicum im. Ludwika Rydygiera, Wydział Lekarski, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Lekarski

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