Projects funded by the NCN


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237 projects found matching your search criteria :

  1. The search for a common structural motif in newly discovered ligands of human ficolin H - endotoxins of Proteus spp.

    Call: PRELUDIUM 4 , Panel: NZ6

    Principal investigator: dr Aleksandra Man-Kupisińska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

  2. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

    Call: SONATA BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Starowicz-Bubak

    Instytut Farmakologii PAN

  3. Search of novel multifunctional ligands targeting neurodegereneration processes.

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Barbara Malawska

    Uniwersytet Jagielloński-Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  4. Taylor dispersion analysis in coiled capillaries at high flow rates - new tool in analytical chemistry for determination...

    Call: OPUS 4 , Panel: ST4

    Principal investigator: prof. Robert Hołyst

    Instytut Chemii Fizycznej PAN

  5. In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Anna Wesołowska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  6. Design, synthesis and properties of novel hybrid materials based on pyridylphosphonic acids.

    Call: PRELUDIUM 1 , Panel: ST5

    Principal investigator: Magdalena Wilk

    Politechnika Wrocławska, Wydział Chemiczny

  7. New ligands with P-P bond - synthesis and structural investigations

    Call: HARMONIA 3 , Panel: ST5

    Principal investigator: prof. Jerzy Pikies

    Politechnika Gdańska, Wydział Chemiczny

  8. Structural study of the complexes of hydrolytic enzymes with heteroorganic substrates and substrate analogs

    Call: OPUS 3 , Panel: ST4

    Principal investigator: dr hab. Jarosław Błaszczyk

    Centrum Badań Molekularnych i Makromolekularnych PAN

  9. Design and modular synthesis of tailor made catalysts of special properties, among others water-soluble and immobilized ...

    Call: OPUS 3 , Panel: ST5

    Principal investigator: dr Oleh Demchuk

    Uniwersytet Marii Curie-Skłodowskiej, Wydział Chemii

  10. A new class of P-stereogenic cyclohexane-based diphosphine ligands - effective application of Birch reduction in organop...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: Magdalena Jaklińska

    Uniwersytet Marii Curie-Skłodowskiej, Wydział Chemii

  11. Pirymidine phosphorothioate analogues of nucleotides as multifunctional regulators of P2Y6 and P2Y14 nucleotide receptor...

    Call: PRELUDIUM 3 , Panel: NZ5

    Principal investigator: Edyta Węgłowska

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  12. Impact of mine waters from lignite open-pit mines on changes of quality and ecological status of river waters and chemis...

    Call: OPUS 1 , Panel: ST10

    Principal investigator: dr Ryszard Staniszewski

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Melioracji i Inżynierii Środowiska

  13. The synthesis of new optically active aziridine alcohols and their application in asymmetric synthesis.

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr hab. Michał Rachwalski

    Uniwersytet Łódzki, Wydział Chemii, Katedra Chemii Organicznej i Stosowanej

  14. Influence of PPAR-gama receptor agonists on antitumor activity of photodynamic therapy.

    Call: PRELUDIUM 3 , Panel: NZ5

    Principal investigator: dr Piotr Mrówka

    Warszawski Uniwersytet Medyczny, Wydział Nauki o Zdrowiu

  15. Studies on activity and immunogenicity of baculovirus-expressed recombinant Plasmodium falciparum EBA-140 ligand binding...

    Call: PRELUDIUM 3 , Panel: NZ6

    Principal investigator: dr Joanna Rydzak

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

  16. Synthesis, structure and reactivity of chiral-at-metal vanadium complexes in aspect of enantioselective catalyst.

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: Ewa Kober

    Uniwersytet Wrocławski, Wydział Chemii

  17. LCAP biomimetics - alicyclic amine derivatives as a new class of monoaminergic receptor ligands

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr hab. Paweł Zajdel

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  18. Search for new "drug-like" molecules designed as adenosine receptors ligands

    Call: HARMONIA 2 , Panel: NZ4

    Principal investigator: prof. Katarzyna Kieć-Kononowicz

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  19. Modeling spectroscopic properties of high-pressure probes for HMF-EMR studies

    Call: HARMONIA 2 , Panel: ST3

    Principal investigator: prof. Czesław Rudowicz

    Zachodniopomorski Uniwersytet Technologiczny w Szczecinie, Wydział Inżynierii Mechanicznej i Mechatroniki, Instytut Fizyki

  20. The effects of histamine receptor signalling suppression on the course and structural and functional consequences of hea...

    Call: HARMONIA 2 , Panel: NZ4

    Principal investigator: prof. Wiesława Fogel

    Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski, Zakład Biochemii Hormonów

  21. Role of CUL4-DDB1-based E3 ligases in the regulation of seed germination and dormancy alleviation of Brassicaceae seeds

    Call: SONATA 2 , Panel: NZ9

    Principal investigator: dr Krystyna Oracz

    SZKOŁA GŁÓWNA GOSPODARSTWA WIEJSKIEGO

  22. Probing molecular recognition by mass spectrometry. A case study: Examination of properties of non-covalent complexes of...

    Call: SONATA 2 , Panel: ST4

    Principal investigator: dr Magdalena Zimnicka

    Instytut Chemii Organicznej PAN

  23. EFFECTS OF ADENOSINE A2A RECEPTOR LIGANDS ON BEHAVIORAL EFFECTS OF ABUSED DRUG (COCAINE) AND NATURAL REWARD (FOOD) USING...

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: Karolina Wydra

    INSTYTUT FARMAKOLOGII PAN

  24. Solution NMR investigations of human cystatin C - structure, dynamics and protein-ligand interactions.

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: Martyna Maszota-Zieleniak

    Uniwersytet Gdański, Wydział Chemii

  25. Conjugated linoleic acid (CLA)-induced transcriptional activation of PPAR-an investigation of molecular machanisms of pu...

    Call: OPUS 2 , Panel: NZ9

    Principal investigator: prof. Teresa Leszczyńska

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

  26. New bioinformatics method for predicting ligand-binding sites in RNA structures

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: dr Anna Philips

    Uniwersytet im. Adama Mickiewicza, Wydział Biologii

  27. The mast cell response to synthetic analogues of viral genomes (TLR3 and TLR7 ligands).

    Call: PRELUDIUM 2 , Panel: NZ6

    Principal investigator: dr Piotr Witczak

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  28. Development of a new scoring function for models of protein-small molecule complexes and its use for studying the mechan...

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: dr Irina Tuszyńska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  29. Mechanisms of contact sensitivity response (CS) mediated via NK cells activated by Toll like receptor (TLR) ligands in m...

    Call: OPUS 2 , Panel: NZ6

    Principal investigator: dr Monika Majewska-Szczepanik

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Nauk o Zdrowiu

  30. Deciphering the promiscuous bioinorganic chemistry of putative copper transporters in bacteria

    Call: SONATA 19 , Panel: ST5

    Principal investigator: dr Aleksandra Hecel-Czaplicka

    Uniwersytet Wrocławski, Wydział Chemii

  31. Insights in the phenylpropanoid transport in model legume plant Medicago truncatula

    Call: SONATA 19 , Panel: NZ9

    Principal investigator: dr Wanda Biała-Leonhard

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  32. Electronic Structure and Electron Transfer Reactions in Selected Molecular Prototypes Involving Non-innocent Ligands: An...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr Piotr Zarzycki

    Instytut Chemii Fizycznej PAN

  33. Playing with Carbene Ligand Rigidity to Control Olefin Metathesis Stability, Productivity and Selectivity

    Call: OPUS 26 , Panel: ST4

    Principal investigator: prof. Karol Grela

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  34. Crownphyrins - hybrids of crown ethers and porphyrins, constituting macrocyclic platforms for the construction of two- a...

    Call: PRELUDIUM BIS 5 , Panel: ST4

    Principal investigator: dr hab. Bartosz Szyszko

    Uniwersytet Wrocławski, Wydział Chemii

  35. Determination of the molecular mechanism of action of TRIM32 E3 ligase in the regulation of adipocytes' function

    Call: PRELUDIUM 22 , Panel: NZ4

    Principal investigator: Katia Alghoz

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  36. Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ...

    Call: PRELUDIUM 22 , Panel: NZ2

    Principal investigator: Nishita Mandal

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  37. New applications of non-conventional nonempirical methodologies for the analysis of catalytic and inhibitory properties ...

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr Edyta Dyguda-Kazimierowicz

    Politechnika Wrocławska

  38. Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Sławomir Filipek

    Uniwersytet Warszawski, Wydział Chemii

  39. Psychedelic-induced molecular changes in the brain

    Call: SONATINA 7 , Panel: NZ2

    Principal investigator: dr Dominik Cysewski

    Uniwersytet Medyczny w Białymstoku

  40. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego PZH - Państwowy Instytut Badawczy

  41. Palladium-catalyzed cascades for the rapid and enantioselective construction of polycyclic scaffolds of alkaloids and ps...

    Call: OPUS 24 , Panel: ST4

    Principal investigator: dr hab. Rafał Loska

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  42. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Sławomir Kasperowicz

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  43. Metallocarbaporphyrinoids as ligands in monomeric and oligomeric complexes. Synthesis, interactions, and catalysis.

    Call: OPUS 23 , Panel: ST4

    Principal investigator: prof. Piotr Chmielewski

    Uniwersytet Wrocławski, Wydział Chemii

  44. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  46. Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sławomir Filipek

    Uniwersytet Warszawski, Wydział Chemii

  47. Metallosupramolecular architectures based on flexidentate pyridyl-β-diketonate ligands - synthesis, properties and catal...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Gracjan Kurpik

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  48. Novel tricyclic glycomimetics as DC-SIGN receptor ligands.

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr Mykhaylo Potopnyk

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  49. Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf...

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Ewelina Honkisz-Orzechowska

    Uniwersytet Jagielloński, Collegium Medicum

  50. Targeting cell surface proteoglycans with high affinity multimeric ligands and their cytotoxic conjugates – towards prec...

    Call: OPUS 22 , Panel: NZ1

    Principal investigator: dr hab. Łukasz Opaliński

    Uniwersytet Wrocławski, Wydział Biotechnologii