Projects funded by the NCN

Optimization of the substrates structure to study deubiquitinating enzymes using methods of combinatorial chemistry

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: Wioletta Rut

Politechnika Wrocławska, Wydział Chemiczny, Zakład Chemii Bioorganicznej

Synthesis of fluorogenic substrates, inhibitors and activity-based probes of human neutrophil proteinase NSP4 and its ev...

Call: OPUS 8 , Panel: ST5

Principal investigator: prof. Adam Lesner

Uniwersytet Gdański, Wydział Chemii

Tailored fluorogenic substrate library with natural / unnatural amino acids in search for specific substrates of matrix ...

Call: OPUS 7 , Panel: ST5

Principal investigator: dr hab. Marcin Drąg

Politechnika Wrocławska, Wydział Chemiczny

The search for novel human proteasome inhibitors and fluorogenic substrates.

Call: SONATA 1 , Panel: ST5

Principal investigator: dr Dawid Dębowski

Uniwersytet Gdański, Wydział Chemii

Aminopeptidases activity profiling in lysates of cell line HeLa using library of fluorogenic substrates

Call: PRELUDIUM 5 , Panel: NZ1

Principal investigator: dr Anna Byzia

Politechnika Wrocławska, Wydział Chemiczny

Unnatural amino acids as a tool for optimization of substrates architecture for targeting human cysteine protease, cathe...

Call: PRELUDIUM 5 , Panel: ST5

Principal investigator: dr Marcin Poręba

Politechnika Wrocławska, Wydział Chemiczny

Combinatorial library of fluorogenic substrates containing natural / unnatural amino acids for substrate specificity pro...

Call: OPUS 2 , Panel: ST5

Principal investigator: dr hab. Marcin Drąg

Politechnika Wrocławska, Wydział Chemiczny

Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

Call: OPUS 21 , Panel: ST4

Principal investigator: dr Wioletta Rut

Politechnika Wrocławska

Dissecting the mechanisms of proteolytic cross-talk underlying pyroptosis, a programmed inflammatory cell death.

Call: OPUS 15 , Panel: NZ1

Principal investigator: dr Marcin Poręba

Politechnika Wrocławska, Wydział Chemiczny