Projects funded by the NCN

Functional, epigenetic and genetic aspects of base excision repair pathway in Alzheimer's disease

Call: OPUS 3 , Panel: NZ7

Principal investigator: dr hab. Tomasz Śliwiński

UNIWERSYTET ŁÓDZKI, Wydział Biologii i Ochrony Środowiska

Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: dr Tomasz Stokłosa

Warszawski Uniwersytet Medyczny, Wydział Lekarski

The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Agnieszka Magdalena Woźniak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Selective PPARγ modulation by amorfrutin B as a novel therapeutic approach to chemotherapy-induced damage to mammalian b...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Bernadeta Pietrzak

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

Call: OPUS 27 , Panel: NZ5

Principal investigator: Kamila Ostrowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Genetic and epigenetic interaction of exposure to endocrine disrupting chemicals included in everyday use products and e...

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Joanna Katarzyna Jurewicz

Instytut Medycyny Pracy im. prof. dr. med. Jerzego Nofera

The role of DNA methylation in enhancing the sensitivity of colorectal cancer cells to topoisomerase inhibitors.

Call: PRELUDIUM 9 , Panel: NZ3

Principal investigator: Alicja Pawlak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

Cultural changes in the evolution of humans and its effects on the epigenetic mechanisms of modern life-style diseases

Call: POLONEZ 1 , Panel: NZ7

Principal investigator: dr Olaf Thalmann

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Karolina Barbara Przepiórska-Drońska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The effect of maternal treatment with metformin in pregnancy and lactation on programming metabolic adverse conditions i...

Call: SONATA BIS 12 , Panel: NZ7

Principal investigator: dr hab. Monika Słupecka-Ziemilska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identificati...

Call: JPND Call 2023 , Panel: NZ5

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu

Semaglutide and neurodevelopment: investigating risks arising from prenatal exposure to a widely popular drug for diabet...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Agnieszka Wnuk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

A search for mechanism of anticancer properities of vitamin C; possible link between epigenetic DNA modyfications and vi...

Call: OPUS 14 , Panel: NZ7

Principal investigator: prof. Ryszard Oliński

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

Search for the mechanisms of the modulation of canonical Wnt signaling which effectively attenuate the survival of head ...

Call: SONATA 7 , Panel: NZ7

Principal investigator: dr Jarosław Paluszczak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Apoptotic mechanisms in skeletal muscle aging; physical exercise intervention

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Barbara Morawin

Uniwersytet Zielonogórski, Wydział Lekarski i Nauk o Zdrowiu

Pharmacogenomics of SGLT2 inhibitors - investigating the role of empagliflozin in epigenetic modification of non-coding ...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Anna Nowak

Warszawski Uniwersytet Medyczny

MicroRNAs in blood as biomarkers for Alzheimer's disease: molecular signature for personalized therapy

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

Call: SONATA 5 , Panel: NZ7

Principal investigator: dr Magdalena Sowa-Kućma

Instytut Farmakologii PAN

Molecular mechanism of epigenetic drugs action to prevent multi-organ injury in a mouse model of sepsis

Call: HARMONIA 6 , Panel: NZ5

Principal investigator: dr Michał Mikula

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

The 11beta-hydroxysteroid dehydrogenase 2 in pregnant women with hypertension

Call: OPUS 3 , Panel: NZ7

Principal investigator: prof. Franciszek Główka

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Drug metabolizing enzymes (DMEs) in liver pathology, proteomic characteristics, transcriptional and epigenetic regulatio...

Call: OPUS 19 , Panel: NZ7

Principal investigator: prof. Marek Droździk

Pomorski Uniwersytet Medyczny w Szczecinie

Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Katarzyna Elżbieta Głombik

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Structure-guided design of histone demethylase inhibitors for cancer therapy.

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Piotr Henryk Małecki

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Environmental and epigenetic modifications and atopy and allergic diseases prevention in rural population at all ages - ...

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr hab. Barbara Ewa Sozańska

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

Identification of epigenetic mechanisms contributing to glioma drug resistance

Call: POLONEZ 3 , Panel: NZ2

Principal investigator: dr Jakub Mieczkowski

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Searching for behavioural and molecular predictors of long-term benzodiazepine administration in preclinical chronic str...

Call: SONATINA 2 , Panel: NZ7

Principal investigator: dr Karolina Kołosowska

Instytut Psychiatrii i Neurologii

The role of epigenetic changes and p53 in visceral adipose tissue in the pathogenesis of type 2 diabetes mellitus

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Janusz Szemraj

Uniwersytet Medyczny w Łodzi, Katedra Biochemii Medycznej

Epigenetics of periodontitis: alterations in the host protein acetylation system as a potentially fundamental mechanism ...

Call: POLONEZ 1 , Panel: NZ7

Principal investigator: dr Aleksander Grabiec

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Using DNA methylation markers and epigenetic clocks as an innovative tool to assess health, risk indicators, and manage ...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Ewelina Pośpiech

Pomorski Uniwersytet Medyczny w Szczecinie

Impact of nanoparticles on cancer metastasis - epigenetic mechanisms

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Marcin Kruszewski

Wyższa Szkoła Informatyki i Zarządzania w Rzeszowie, Wydział Medyczny

Polystyrene nanoparticles and their epigenetic and genotoxic properties in human peripheral blood mononuclear cells

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Kinga Malinowska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Nanoplastic toxicity: effect on gut-brain axis

Call: OPUS 18 , Panel: NZ7

Principal investigator: prof. Marcin Konrad Kruszewski

Instytut Chemii i Techniki Jądrowej