Projects funded by the NCN


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127 projects found matching your search criteria :

  1. The study on the mechanism of vitamin D analogues anticancer action in combination with anastrozole in a human breast ca...

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Beata Filip-Psurska

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

  2. Development of methods for the synthesis of flourinated isoselenocyanate sulforaphane analogs with expected improved ant...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: Tomasz Cierpiał

    Centrum Badań Molekularnych i Makromolekularnych PAN

  3. Synthesis of mononucleotide N2,N2,7-trimethylguanosine cap analogues as translation inhibitors in Ascaris suum

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: dr Karolina Piecyk

    Uniwersytet Warszawski, Wydział Chemii

  4. Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

    Call: SONATA 1 , Panel: ST5

    Principal investigator: dr Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  5. Peptide splicing - the mechanism and its application for designing compounds with potential use in medicinal practice

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Krzysztof Rolka

    Uniwersytet Gdański, Wydział Chemii

  6. The mast cell response to synthetic analogues of viral genomes (TLR3 and TLR7 ligands).

    Call: PRELUDIUM 2 , Panel: NZ6

    Principal investigator: dr Piotr Witczak

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  7. Stereodefined phosphorothioate Glycol Nucleic Acids (GNA) - synthesis and physico-chemical properties.

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr Agnieszka Tomaszewska-Antczak

    Centrum Badań Molekularnych i Makromolekularnych PAN

  8. Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Piotr Guga

    Centrum Badań Molekularnych i Makromolekularnych PAN

  9. Design, synthesis and biological evaluation of methylthio analogues of combretastatin A-4 - potential antimitotic agents

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Stanisław Sobiak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  10. The influence of tunicamycin analogues and mimetics on hepatitis C virus (HCV) propagation.

    Call: PRELUDIUM 2 , Panel: NZ6

    Principal investigator: dr Ewelina Król

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  11. Synthesis of deltorphin I and dermorphin analogues modified with alfa-alkyl-beta-azido(amino)alanine in postion 2 or 3.

    Call: PRELUDIUM 2 , Panel: ST5

    Principal investigator: Anika Lasota

    POLITECHNIKA ŁÓDZKA, Politechnika Łódzka, Wydział Chemiczny,

  12. Application of defect engineering and electronic structure engineering in the elaboration of Prussian blue analogues bas...

    Call: OPUS 26 , Panel: ST11

    Principal investigator: prof. Janina Molenda

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Energetyki i Paliw

  13. Design and synthesis of new rifampicin analogs as a source of effective bacterial RNA polymerase inhibitors

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Piotr Przybylski

    Uniwersytet im. Adama Mickiewicza, Wydział Chemii

  14. Biomimetic analogues of siderophores as structural probes for microbial iron uptake processes

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Elżbieta Gumienna-Kontecka

    Uniwersytet Wrocławski, Wydział Chemii

  15. Machine learning and advanced NMR crystallography - complementary tools for optimizing the pathways of synthesis, predic...

    Call: OPUS 24 (LAP) , Panel: ST4

    Principal investigator: prof. Marek Potrzebowski

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  16. Exploring the unknown drug-like chemical space: new classes of sulfoximine derivatives and their biological activities.

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr hab. Maciej Dawidowski

    Warszawski Uniwersytet Medyczny

  17. Are MCPIP1 and MCPIP3 analogous or opposite players in the maintenance of skin function?

    Call: SONATA 18 , Panel: NZ3

    Principal investigator: dr Agata Lichawska-Cieślar

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  18. In vitro and in vivo investigations of the radiometals influence on the ability of CCK2R receptors imaging by the radiol...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Renata Mikołajczak

    Narodowe Centrum Badań Jądrowych

  19. Design, synthesis and in vitro and in vivo studies of anticancer potential of phosphonic and phosphinic analogs of sulfo...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: prof. Tadeusz Gajda

    POLITECHNIKA ŁÓDZKA, Wydział Chemiczny

  20. Plastic-(not)fantastic? Effect of bisphenol A and its analogues on calcium homeostasis in mammalian oocytes.

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr hab. Anna Ajduk

    Uniwersytet Warszawski, Wydział Biologii

  21. Laser Emission of Thioflavin T and its analogues to uncover the early symptoms of neurodegenerative diseases.

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Piotr Hańczyc

    Uniwersytet Warszawski, Wydział Fizyki

  22. P-stereodefined phosphorothioate analogs of 'morpholino" oligonucleotides (sTMO) as a new model of therapeutic nucleic a...

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Katarzyna Jastrzębska

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  23. New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Olga Ciupak

    Politechnika Gdańska, Wydział Chemiczny

  24. Switchable with visible light cisplatin analogs and complexes of selected transition metals - photochemical and anticanc...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Krzysztof Szczubiałka

    Uniwersytet Jagielloński, Wydział Chemii

  25. Synthetic analogs of minerals as advanced Cu-based solid-solution photocatalysts

    Call: PRELUDIUM 20 , Panel: ST10

    Principal investigator: Edyta Waluś

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Geologii, Geofizyki i Ochrony Środowiska

  26. The study of adsorption mechanisms of N-benzenamino(boronphenyl)methylphosphonic acids on different metal surfaces

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: dr Natalia Piergies

    Uniwersytet Jagielloński, Wydział Chemii

  27. Photodynamics of metal complexes with 2,6-bis(thiazol-2-yl)pyridine derivatives functionalized by aryls and N-donors as ...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Anna Maroń

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  28. Preparation and evaluation of biological activity of new biotinylated hop flavonoid analogues.

    Call: SONATA 16 , Panel: NZ9

    Principal investigator: dr hab. Monika Stompor-Gorący

    Uniwersytet Rzeszowski

  29. The effect of methylated resveratrol analogue 3,4,4',5-tetramethoxystilbene (DMU-212) on secretion profile and different...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Małgorzata Józkowiak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  30. Influence of rapidly progressing climate change on polar marine organisms - investigations along naturally occurring env...

    Call: OPUS 19 , Panel: ST10

    Principal investigator: prof. Piotr Kukliński

    Instytut Oceanologii Polskiej Akademii Nauk

  31. Neuromimetic effects in perovskites and their analogues

    Call: ETIUDA 8 , Panel: ST5

    Principal investigator: Piotr Zawal

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Akademickie Centrum Materiałów i Nanotechnologii AGH

  32. Modeling of mechanical properties of hemicellulose-cellulose networks in plant cell wall analogues

    Call: SONATA 15 , Panel: NZ9

    Principal investigator: dr Piotr Pieczywek

    Instytut Agrofizyki im. Bohdana Dobrzańskiego Polskiej Akademii Nauk

  33. Application of N-(2-thioethyl)glycine analogues in orthogonal cleavage of peptides from solid support

    Call: PRELUDIUM 18 , Panel: ST4

    Principal investigator: Magdalena Wierzbicka

    Uniwersytet Wrocławski, Wydział Chemii

  34. Novel analogs of human cathelicidin (LL-37) with enhanced resistant to enzymatic degradation. Design chemical synthesis ...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: prof. Adam Lesner

    Uniwersytet Gdański, Wydział Chemii

  35. Synthetic analogues of opioid growth factor linked to derivatives of glucosamine as a potential compounds for targeted t...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Iwona Inkielewicz-Stępniak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  36. Conformational studies of selected neurohypophyseal hormone analogues in a membrane-mimicking environment

    Call: PRELUDIUM 1 , Panel: ST4

    Principal investigator: dr Emilia Lubecka

    Uniwersytet Gdański, Wydział Chemii

  37. Designing modified mRNAs as vaccines and therapeutic protein carriers. Studies on their immunogenicity in the context of...

    Call: OPUS 17 , Panel: NZ1

    Principal investigator: prof. Edward Darżynkiewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  38. Gut microbiota dependent modulation of therapeutic response and side effects to irinotecan and new camptothecin analogue...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jerzy Ostrowski

    Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

  39. A new gereration of anticancer pronucleotides

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Jacek Stawiński

    Instytut Chemii Bioorganicznej PAN

  40. New calcitriol analogues with unnatural D ring

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: Adrian Fabisiak

    Uniwersytet Warszawski, Wydział Chemii

  41. Gold and silver nanoparticles as carriers for delivery of 5' end mRNA cap analogues with potential therapeutical applica...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Marzena Jankowska-Anyszka

    Uniwersytet Warszawski, Wydział Chemii

  42. Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new struc...

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: dr Justyna Gołębiewska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  43. Chemical synthesis of 1-O-acyl-2-O-methyl-3-O-phosphodiester and 1-O-acyl-2-O-methyl-3-O-phosphorothioate analogs of sel...

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Andrzej Okruszek

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  44. Synthesis and the properties studies of Prussian blue analogues nanorods

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: Wojciech Sas

    Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

  45. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  46. Synthetic alakloid analogues: aminoalcohols beyond the chiral pool

    Call: SONATA BIS 8 , Panel: ST5

    Principal investigator: dr hab. Przemysław Boratyński

    Politechnika Wrocławska

  47. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  48. The biological activity of the gonadoinhibitory peptides and nanodiamonds conjugates in the Tenebrio molitor beetle.

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Patryk Nowicki

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  49. The role of extracellular ATP fraction in induction of epithelial-mesenchymal transition - studies using analogs of nucl...

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Róża Pawłowska

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  50. SILVERLAND. Unique silver route to superconducting cuprate analogs.

    Call: MAESTRO 9 , Panel: ST5

    Principal investigator: prof. Wojciech Grochala

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego