Projects funded by the NCN


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192 projects found matching your search criteria :

  1. Role of CUL4-DDB1-based E3 ligases in the regulation of seed germination and dormancy alleviation of Brassicaceae seeds

    Call: SONATA 2 , Panel: NZ9

    Principal investigator: dr Krystyna Maria Oracz

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

  2. Lipid-Proteasome Interplay in Aging and Proteostasis

    Call: SONATINA 9 , Panel: NZ1

    Principal investigator: Pankaj Thapa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  3. Nitroxyl's role in the signaling cross-talk between cell death and life during potato leaves' hypersensitive response to...

    Call: OPUS 28 , Panel: NZ9

    Principal investigator: prof. Magdalena Arasimowicz-Jelonek

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  4. Tick-borne encephalitis virus protease as a molecular target for novel inhibitors and activity-based probes

    Call: OPUS 28 , Panel: NZ6

    Principal investigator: dr Renata Grzywa

    Politechnika Wrocławska

  5. Where Inhibition is not Enough- Development of Innovative Compounds for Targeted Degradation of Extracellular and Membra...

    Call: OPUS 28 (LAP) , Panel: NZ5

    Principal investigator: dr Marcin Skoreński

    Politechnika Wrocławska

  6. Development of cIAP1-targeting CDK4/6 degraders (PROTACs) containing a phosphoroorganic warhead (POWERTAP)

    Call: SONATA 20 , Panel: NZ3

    Principal investigator: dr Agnieszka Łupicka-Słowik

    Politechnika Wrocławska

  7. The first antibody-drug conjugates for Alzheimer's disease therapy

    Call: SONATA BIS 14 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  8. Molecular factors and pathomechanism of cancer-associated cachexia.

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr hab. Marcin Tomasz Skrzypski

    Gdański Uniwersytet Medyczny

  9. Mitochondrial quality control in plants: the relationship between mitophagy and the mitochondrial inner membrane proteas...

    Call: OPUS 27 , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Heidorn-Czarna

    Uniwersytet Wrocławski

  10. Unique metallopeptidase (family M97) in Bacteroidota's species biology and pathogenicity

    Call: OPUS 27 , Panel: NZ1

    Principal investigator: prof. Jan Stanisław Potempa

    Uniwersytet Jagielloński

  11. 'Trojan horse' mechanism used by Candida albicans Sap6 protease in evading neutrophil response

    Call: OPUS 27 , Panel: NZ6

    Principal investigator: dr Marcin Michał Zawrotniak

    Uniwersytet Jagielloński

  12. Phoenixin as a new factor regulating maternal-embryonic communication in the peri-implantation period - multi-omics appr...

    Call: OPUS 27 , Panel: NZ9

    Principal investigator: dr hab. Agata Żmijewska

    Uniwersytet Warmińsko-Mazurski w Olsztynie

  13. Probable molecular mechanism of transmission of the spirochete Borrelia burgdorferi sensu lato - comparative studies of ...

    Call: PRELUDIUM 23 , Panel: NZ6

    Principal investigator: Magdalena Szczotko

    Uniwersytet Warmińsko-Mazurski w Olsztynie

  14. Endurance ability– multiomics investigation of organism adaptation to long lasting effort based on Arabian horses model...

    Call: PRELUDIUM 23 , Panel: NZ9

    Principal investigator: Grzegorz Myćka

    Instytut Zootechniki - Państwowy Instytut Badawczy

  15. Polyphosphate condensates in regulation of proteases' localization and activity in stressed Escherichia coli cells

    Call: PRELUDIUM 23 , Panel: NZ1

    Principal investigator: Zuzanna Karolina Hirsz

    Uniwersytet Gdański

  16. Analysis od selected physiological processes and alterations within cauliflower mitochondrial proteome under drought str...

    Call: OPUS 2 , Panel: NZ9

    Principal investigator: dr Włodzimierz Zygmunt Krzesiński

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Ogrodnictwa i Architektury Krajobrazu

  17. Nuclear protein quality control in neurodegeneration

    Call: SONATA 19 , Panel: NZ3

    Principal investigator: dr Lidia Wróbel

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  18. Nesfatin-1, the new hormone controlling the pig reproductive system: studies of the transcriptome, proteome, metabolome ...

    Call: OPUS 26 , Panel: NZ9

    Principal investigator: prof. Tadeusz Szczepan Kamiński

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  19. Protease-induced neutrophilic networks in cancer development.

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Danuta Teresa Bryzek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  20. PROteolysis TArgeting Chimeras (PROTACs) intended to knock down excessive amyloidogenic proteins, human islet amyloid po...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  21. Proteolytic processing of adhesion G-protein coupled receptors through proteases

    Call: WEAVE-UNISONO , Panel: NZ1

    Principal investigator: dr Renata Katarzyna Mężyk-Kopeć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  22. The role of extracytoplasmic proteases in the physiology and morphology of the bacterium Helicobacter pylori

    Call: SONATA 19 , Panel: NZ2

    Principal investigator: dr Urszula Zarzecka

    Uniwersytet Gdański, Wydział Biologii

  23. Exploring the Impact of Salmonella on the Ubiquitin-Proteasome System

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr Grzegorz Jan Grabe

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  24. Macrocyclic peptides for targeting of membrane-anchored serine protease

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  25. Bacterial Meltome Atlas and its use in the assessment of bacterial sensitivity to temperature in the context of infectio...

    Call: SONATA BIS 13 , Panel: NZ2

    Principal investigator: dr Anna Ewelina Jarząb

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  26. Unraveling protease activation in stimulated CAR-T cells to identify new biomarkers for assessing their clinical efficac...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  27. Impact of OMA1 protease on aggregation-prone proteins associated with neurodegenerative diseases.

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Magda Alicja Krakowczyk

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  28. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  29. Mitochondrial stress induced proteasome

    Call: SONATA 18 , Panel: NZ5

    Principal investigator: dr Agata Kodroń

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  30. Biological membranes and macromolecular crowding in the function of the hepatitis C virus proteases

    Call: PRELUDIUM BIS 4 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  31. Bunyaviral strategies to reorganize and exploit cellular translation

    Call: SONATA BIS 12 , Panel: NZ1

    Principal investigator: dr Piotr Gerlach

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  32. Role of neutrophil serine proteases in chronic inflammatory skin diseases associated with Regnase-1 malfunction

    Call: OPUS 23 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  33. The identification of new components of the plant mitochondrial proteolytic system based on yeast known homologs

    Call: SONATA 2 , Panel: NZ1

    Principal investigator: dr Iwona Dorota Migdał

    Uniwersytet Wrocławski, Wydział Biotechnologii

  34. Epigenetic traces of anhydrobiosis: a study of DNA and protein modifications through tardigrade generations

    Call: PRELUDIUM BIS 3 , Panel: NZ4

    Principal investigator: dr hab. Robert Nawrot

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  35. Evaluation of the brain microbiome and proteome as well as the role of fecal microbiota transplantation (FMT) in schizop...

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Dominika Salamon

    Uniwersytet Jagielloński, Collegium Medicum

  36. The structures, biochemistry, physiology, and evolution of bacterial α2-macroglobulins from the human periodontopathogen...

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  37. Adaptation of Proteins to Evade Premature Degradation by the Ubiquitin-Proteasome System

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr hab. Wojciech Mieczysław Pokrzywa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  38. Role of DPPIV family proteases in transposon silencing and genome maintenance

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Rajani Kanth Gudipatti

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  39. The role of obestatin in the porcine uterus during the oestrous cycle and early pregnancy

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: dr Grzegorz Tomasz Kopij

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  40. Mechanism of biofilm formation by uropatogenic E. coli producing fimbrial adhesin Dr - studies of proteome and metabolom...

    Call: OPUS 21 , Panel: NZ6

    Principal investigator: dr hab. Rafał Piątek

    Politechnika Gdańska, Wydział Chemiczny

  41. Role of GAB glutaminase in glioblastoma.

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Monika Paulina Szeliga

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  42. Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: prof. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  43. Comprehensive analysis of frost tolerance mechanisms in the sequence of cold acclimation, de-acclimation and re-acclimat...

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr Dawid Bogdan Perlikowski

    Instytut Genetyki Roślin PAN

  44. The study of adsorption mechanisms of N-benzenamino(boronphenyl)methylphosphonic acids on different metal surfaces

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: dr Natalia Anna Piergies

    Uniwersytet Jagielloński, Wydział Chemii

  45. Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Wioletta Katarzyna Rut

    Politechnika Wrocławska

  46. The role of neutrophil serine proteases in the regulation of function of the podocyte and glomerular filtration barrier.

    Call: OPUS 21 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  47. Identification of natural substrates and physiological partners of mitochondrial AtFtsH4 protease from Arabidopsis thali...

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: dr Elwira Smakowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  48. Living on the edge: evolutionary adaptation of substrate-recruiting subunits of the cullin-RING ubiquitin ligase complex...

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: Natalia Anna Szulc

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  49. Expanding the mitochondrial proteome via the non-canonical translation mechanisms

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: prof. Joanna Kufel

    Uniwersytet Warszawski, Wydział Biologii

  50. Molecular and physiological basis of seeds priming as a strategy improving salinity tolerance of germinating rape seeds ...

    Call: OPUS 2 , Panel: NZ9

    Principal investigator: dr hab. Małgorzata Garnczarska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii