Projects funded by the NCN

Selective recognition of toxic heteroaromatic amines and N-nitrosamines in protein providing food products

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Włodzimierz Kutner

Instytut Chemii Fizycznej PAN

Study of iron catalysis for the activation of carbon-hydrogen bonds: design of new reactions and their application in me...

Call: SONATA 8 , Panel: ST5

Principal investigator: dr Michał Szostak

Uniwersytet Opolski, Wydział Chemii

Synthesis and pharmacological evaluation of novel benzizoxazolepropylpyrolidine derivatives as multifunctional ligands w...

Call: SONATA 8 , Panel: NZ7

Principal investigator: dr Monika Marcinkowska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Enzymatic catalysis as a versatile tool for the synthesis of 1,3-dimethylxanthine derivatives with potential anticancer ...

Call: PRELUDIUM 7 , Panel: ST5

Principal investigator: dr Paweł Borowiecki

Politechnika Warszawska, Politechnika Warszawska

New inhibitors of catalytic subunit of telomerase.

Call: OPUS 7 , Panel: NZ7

Principal investigator: prof. Maciej Bagiński

Politechnika Gdańska, Wydział Chemiczny

Metabolomic analysis of prostate cancer with the use of analytical techniques hyphenated with mass spectrometry and adva...

Call: SONATA 7 , Panel: NZ7

Principal investigator: dr Wiktoria Struck-Lewicka

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Optimization of analytical methods in order to apply them to determination of water-soluble vitamins in ultrafiltrates o...

Call: PRELUDIUM 5 , Panel: NZ7

Principal investigator: Dorota Wirkus

Uniwersytet Gdański, Wydział Chemii

Elaboration of anti-cancer drug implantational delivery system immobilized on polymer matrix

Call: OPUS 5 , Panel: ST5

Principal investigator: dr Andrzej Plichta

Politechnika Warszawska, Wydział Chemiczny

Ocena fotochemiczna porfirazyn i ftalocyjanin z podstawnikami heterocyklicznymi i alkoksylowymi o potencjalnym zastosowa...

Call: ETIUDA 1 , Panel: NZ7

Principal investigator: Łukasz Sobotta

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Studies on generation conditions and identification of reactive intermediates from model antitumor acridinone derivative...

Call: SONATA 4 , Panel: NZ7

Principal investigator: dr Agnieszka Potęga

Politechnika Gdańska, Wydział Chemiczny

Towards an understanding the nature of environmental release and exposure of nanoparticles

Call: SONATA 4 , Panel: NZ7

Principal investigator: dr Celina Sikorska

Uniwersytet Gdański, Wydział Chemii

Drug Design: Chirality Measures as QSAR descriptors.

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: Piotr Lipiński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Identyfication of biologically active compounds of Dermestes maculatus and Dermestes ater as compounds with antifungal p...

Call: PRELUDIUM 3 , Panel: NZ4

Principal investigator: Magdalena Cerkowniak

Uniwersytet Gdański, Wydział Chemii

Multicomponent, metathesis reactions, and biotransformations as usefull tools in synthesis of anticancer peptydomimetics

Call: PRELUDIUM 2 , Panel: ST5

Principal investigator: Szymon Kłossowski

Instytut Chemii Organicznej PAN

Design, synthesis and biological evaluation of Steroid Sulfatase Inhibitors based on organophosphorus compounds.

Call: SONATA 2 , Panel: NZ7

Principal investigator: dr Sebastian Demkowicz

POLITECHNIKA GDAŃSKA

Synthesis and application of new mixed-mode materials to study the metabolism of drugs used in Poland for the treatment ...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Sylwia Studzińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

Assessment of twin screw extrusion potential as a continuous and scalable method of mechanochemical synthesis of active ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Anna Gołkowska

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny

Feel the chemistry if you're close enough - proximity-induced SuFEx ligation for mRNA biology and medicine

Call: OPUS 25 , Panel: ST5

Principal investigator: prof. Jacek Jemielity

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Chemosensors with molecularly imprinted polymers for determination of antiviral active drug substances in body fluids - ...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr Krzysztof Noworyta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Design, Synthesis and Characterization of Functionalized 1,2,4-Trioxanes/Trioxepanes for Antimalarial and Anticancer Use

Call: SONATINA 7 , Panel: NZ7

Principal investigator: dr Mohit Tiwari

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

CHIRAL RHENIUM AND RHODIUM COMPLEXES OF ANTICANCER AND ANTIBACTERIAL ACTIVITY: SYNTHESIS, ACTIVITY, AND PHYSICOCHEMICAL ...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Jan Dobrowolski

Narodowy Instytut Leków

Step beyond classical lipophilicity - modeling of phospholipids affinity using immobilized artificial membranes chromato...

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr hab. Krzesimir Ciura

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Exploring the unknown drug-like chemical space: new classes of sulfoximine derivatives and their biological activities.

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr hab. Maciej Dawidowski

Warszawski Uniwersytet Medyczny

Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP...

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Natalia Karska

Uniwersytet Gdański, Wydział Chemii

A smart stride for cancer: synergistic effect of co-delivery chemo- andphototherapeutic agents using magneto-fluorescent...

Call: POLONEZ BIS 2 , Panel: NZ7

Principal investigator: dr Prachi Ghoderao

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The assessment of purity and identity confirmation of extracellular vesicles withcapillary electrophoresis

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Aleksandra Steć

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Bionanoparticles with a molecular targeting device as a weapon for breast cancer

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Sylwia Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Kinga Czarnota-Łydka

Uniwersytet Jagielloński, Collegium Medicum

The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Maciej Spiegel

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny

Characteristics and health effects of the suspended fraction present in the indoor environment of elderly care and child...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Bożena Zabiegała

Politechnika Gdańska

Impact of the CDK4/6 targeted degradation by PROTACs on immune checkpoint signaling in cancer

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr Katarzyna Magiera-Mularz

Uniwersytet Jagielloński, Wydział Chemii

Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Papaj

Politechnika Śląska, Centrum Biotechnologii

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Olga Ciupak

Politechnika Gdańska, Wydział Chemiczny

Switchable with visible light cisplatin analogs and complexes of selected transition metals - photochemical and anticanc...

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Krzysztof Szczubiałka

Uniwersytet Jagielloński, Wydział Chemii

Novel BODIPY derivatives and ruthenium complexes conjugates as photosensitizers for bacterial inactivation in the in viv...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Weronika Porolnik

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Sylwia Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search...

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Marcin Kołaczkowski

Uniwersytet Jagielloński, Collegium Medicum

The isolation of phenolic components of Zingiber officinale extracts and the assessment of their anticonvulsant activity...

Call: OPUS 21 , Panel: NZ4

Principal investigator: dr hab. Wirginia Kukuła-Koch

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

Call: OPUS 21 , Panel: NZ7

Principal investigator: dr Dawid Panek

Uniwersytet Jagielloński, Collegium Medicum

A new class of antimicrobial compounds. Design, synthesis and study of the mechanism of action.

Call: PRELUDIUM BIS 2 , Panel: NZ7

Principal investigator: dr hab. Sylwia Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Paulina Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Tomasz Wróbel

Uniwersytet Medyczny w Lublinie

Quinoxalino-2,3-diones as potent tools for exploration of ionotropic kainate receptors

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Ewa Szymańska

Uniwersytet Jagielloński, Collegium Medicum

Make an old drug great again – isoniazid/rifamycin-boron clusters conjugates – synthesis and antitubercular activity....

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Olejniczak

Instytut Biologii Medycznej Polskiej Akademii Nauk

Ionotropic gelation and chemical crosslinking as tools to obtain matrix capsules with mesalazine

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Piotr Gadziński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Mechanistic clarification of the interaction of nanoparticles and nanoscale coordination compounds at the interface of m...

Call: OPUS 19 , Panel: ST4

Principal investigator: prof. Rudi van Eldik

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Towards innovative strategy for treatment of Alzheimer's Disease via dual inhibition of receptor 5-HT6 and kinase CDK5.

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Sylwia Sudoł

Uniwersytet Jagielloński, Collegium Medicum

New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Karol Biernacki

Politechnika Gdańska, Wydział Chemiczny