Projects funded by the NCN
Multicomponent, metathesis reactions, and biotransformations as usefull tools in synthesis of anticancer peptydomimetics
2011/03/N/ST5/04353
Keywords:
medicinal chemistry Ugi reaction peptydomimetics metathesis
Descriptors:
- ST5_16:
- ST5_23:
- NZ1_9: Biotechnology
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Instytut Chemii Organicznej PAN
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 2 - announced on 2011-09-15
Amount awarded: 123 750 PLN
Project start date (Y-m-d): 2012-08-27
Project end date (Y-m-d): 2014-08-26
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (2)
- Model Studies On the First Example of the Enzyme-Catalyzed Ugi reactionAuthors:Szymon Kłossowski, Barbara Wiraszka, Stanisław Berłożecki, Ryszard OstaszewskiAcademic press:Organic Letters (rok: 2013, tom: 15, strony: 566-569), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/ol3033829 - link to the publication
- Chemoenzymatic synthesis and application of a new, easily cleavable chiral auxiliary for the synthesis of peptidomimetics via an Ugi reactionAuthors:Szymon Klossowski, Anna Brodzka, Małgorzata Zysk, Ryszard OstaszewskiAcademic press:Tetrahedron: Asymmetry (rok: 2014, tom: 25, strony: 8), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.tetasy.2014.01.016 - link to the publication