Projects funded by the NCN

Amine derivatives of hydantoin as selective 5-HT7 receptor ligand. Molecular modeling, synthesis and pharmacological eva...

Call: PRELUDIUM 8 , Panel: NZ7

Principal investigator: Katarzyna Kucwaj-Brysz

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum Uniwersytet Jagielloński, Wydział Farmaceutyczny

The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r...

Call: OPUS 6 , Panel: NZ4

Principal investigator: prof. Grzegorz Hess

Instytut Farmakologii PAN

The role of dystroglycan in synaptic plasticity modulated by small Rho GTPases

Call: PRELUDIUM 5 , Panel: NZ3

Principal investigator: Monika Bijata

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE...

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Maciej Pawłowski

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

In the search for active compounds among ligands of serotonin, particularly 5-HT7, and dopamine receptors, with potentia...

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Anna Wesołowska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: Grzegorz Satała

Instytut Farmakologii PAN

LCAP biomimetics - alicyclic amine derivatives as a new class of monoaminergic receptor ligands

Call: OPUS 3 , Panel: NZ7

Principal investigator: dr hab. Paweł Zajdel

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Targeting the serotonin 5-HT7 receptor in a search for new strategies of mental disorders treatment

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Patryk Pyka

Uniwersytet Jagielloński, Collegium Medicum

Molecular mechanisms of 5-HT7R-mediated resilience in stress-related disorders

Call: OPUS 21 , Panel: NZ4

Principal investigator: prof. Jakub Włodarczyk

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

The place does matter - 5-HT7R-mediated structural plasticity in the specific hippocampal subregions

Call: SONATA 15 , Panel: NZ4

Principal investigator: dr Monika Bijata

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

Call: OPUS 17 , Panel: NZ7

Principal investigator: prof. Paweł Zajdel

Uniwersytet Jagielloński, Collegium Medicum

Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

Call: OPUS 16 , Panel: NZ2

Principal investigator: dr hab. Sabina Podlewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr...

Call: SONATINA 2 , Panel: NZ7

Principal investigator: dr Sabina Podlewska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Andrzej Bojarski

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: dr Agnieszka Jankowska

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

Call: PRELUDIUM 12 , Panel: NZ4

Principal investigator: Marcin Siwiec

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of halogen bonding in interaction of ligands with SERT.

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Jakub Staroń

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Modulation of amygdala neural network activity by the 5-HT7 receptor

Call: OPUS 11 , Panel: NZ4

Principal investigator: prof. Krzysztof Tokarski

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Call: HARMONIA 7 , Panel: NZ7

Principal investigator: Sabina Podlewska

Instytut Farmakologii PAN