Projects funded by the NCN

DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

Call: OPUS 8 , Panel: NZ5

Principal investigator: dr hab. Elżbieta Speina

Instytut Biochemii i Biofizyki PAN

Efficiency of photodynamic reaction enhanced electroporation in human cancer cells sensitive and resistant to chemothera...

Call: SONATA 1 , Panel: NZ4

Principal investigator: dr Julita Kulbacka

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

Role of the PARP1/HPF1 complex in the conferring of resistance to doxorubicin in triple negative breast cancer

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Magdalena Strachowska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

New strategy for overcoming resistance to chemotherapy of ovarian cancer by modulation of the canonical and non-canonica...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Radosław Januchowski

Uniwersytet Zielonogórski, Collegium Medicum

Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Carlo Vascotto

Instytut Hematologii i Transfuzjologii

Analysis of semaphorin 3 (SEMA3), protocadherin 9 (PCDH9) and S 100 calcium binding proteinA3 (S100A3) expression in pro...

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr hab. Radosław Januchowski

Uniwersytet Zielonogórski, Collegium Medicum

Changes in lipid metabolism of resistant to BRAF/MEK inhibitors human melanoma cells associated with the presence of adi...

Call: SONATA 16 , Panel: NZ5

Principal investigator: dr Aleksandra Simiczyjew

Uniwersytet Wrocławski, Wydział Biotechnologii

Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Marek Jamrozik

Uniwersytet Jagielloński, Collegium Medicum

Concept of the universal antibody targeting tumor cells resistant to first-line immunotherapeutics.

Call: OPUS 18 , Panel: NZ6

Principal investigator: dr hab. Marcin Okrój

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Identifying and overcoming mechanisms promoting resistance to venetoclax in B cell acute lymphoblastic leukemia with MLL...

Call: PRELUDIUM 16 , Panel: NZ5

Principal investigator: dr Klaudyna Fidyt

Warszawski Uniwersytet Medyczny, Wydział Lekarski

The significance of cancer specific PFK-II (PFKFB3 and PFKFB4) isoenzymes inhibition in overcoming resistance to BRAF in...

Call: PRELUDIUM 16 , Panel: NZ5

Principal investigator: Sonia Trojan

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass pr...

Call: PRELUDIUM 15 , Panel: NZ5

Principal investigator: Tadeusz Kubicki

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

Regulation of epithelial to mesenchymal transition and therapy resistance to antitumor therapies by MCPIP1

Call: SONATA BIS 7 , Panel: NZ5

Principal investigator: dr hab. Katarzyna Miękus

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Proteomic analysis of myeloma plasma cells to determine proteins and pathways involved in acquired resistance to proteas...

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr hab. Dominik Dytfeld

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

Call: PRELUDIUM 13 , Panel: NZ5

Principal investigator: dr Anna Rafało-Ulińska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Evaluation of anticancer potential of glutamine metabolism modulation in multiple myeloma sensitive and resistant to che...

Call: PRELUDIUM 11 , Panel: NZ5

Principal investigator: Monika Prełowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Protein and gene expression analysis in the course of renal cancer stem-like cells' primary resistance to sorafenib in h...

Call: PRELUDIUM 9 , Panel: NZ5

Principal investigator: Zofia Bielecka

Wojskowy Instytut Medyczny