Projects funded by the NCN

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Information of the project and the call

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The role of Diaph1 signaling in diabetic neuropathy pathogenesis

2018/30/E/NZ5/00458

Keywords:

Diaph1 RAGE cytoskeleton diabetic neuropathy axonal transport

Descriptors:

  • NZ5_3:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Lekarski

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Judyta Karolina Juranek 

Number of co-investigators in the project: 5

Call: SONATA BIS 8 - announced on 2018-06-15

Amount awarded: 3 837 200 PLN

Project start date (Y-m-d): 2019-07-01

Project end date (Y-m-d): 2024-06-30

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (3)
  1. The cross-talk between RAGE and DIAPH1 in neurological complications of diabetes: A review
    Authors:
    Kamila Zglejc-Waszak , Konark Mukherjee, Judyta Karolina Juranek
    Academic press:
    European Journal of Neuroscience (rok: 2021, tom: 54(6), strony: 5982-5999), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/ejn.15433 - link to the publication
  2. A mouse model of uterine exposure to long-term hyperglycemia and a high-fat diet
    Authors:
    Zglejc-Waszak K, Korytko A, Pomianowski A, Wojtkiewicz J, Wąsowicz K, Juranek JK
    Academic press:
    Animal Science Papers and Reports (rok: 2024, tom: 4 (2024), strony: 203-216), Wydawca: Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, Jastrzębiec, Poland
    Status:
    Published
    DOI:
    10.2478/aspr-2023-0031 - link to the publication
  3. Peripheral Neuropathy Presents Similar Symptoms and Pathological Changes in Both High-Fat Diet and Pharmacologically Induced Pre- and Diabetic Mouse Models
    Authors:
    Julia Jaroslawska, Agnieszka Korytko, Kamila Zglejc-Waszak, Tomasz Antonowski, Andrzej S Pomianowski, Krzysztof Wasowicz, Joanna Wojtkiewicz, Judyta K Juranek
    Academic press:
    Life (Basel) (rok: 2021, tom: 11, strony: 1267), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/life11111267 - link to the publication
  4. Novel insights into the nervous system affected by prolonged hyperglycemia
    Authors:
    Zglejc-Waszak Kamila, Mukherjee Konark, Korytko Agnieszka, Lewczuk Bogdan, Pomianowski Andrzej, Wojtkiewicz Joanna A., Banach Marta, Załęcki Michał, Nowicka Natalia, Jarosławska Julia, Kordas Bernard, Wąsowicz Krzysztof, Juranek Judyta.
    Academic press:
    Journal of Molecular Medicine (rok: 2023, tom: 101, strony: 1015-1028), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00109-023-02347-y - link to the publication
  5. New insights into RAGE/Diaph1 interaction as a modulator of actin cytoskeleton dynamics in peripheral nervous system in long-term hyperglycaemia
    Authors:
    Zglejc-Waszak Kamila, Pomianowski Andrzej, Wojtkiewicz Joanna A., Banach Marta, Juranek Judyta.
    Academic press:
    European Journal of Neuroscience (rok: 2023, tom: 57(10), strony: 1642-1656), Wydawca: Federation of European Neuroscience Societies and John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/ejn.15991 - link to the publication
  6. Mammalian Diaphanous1 signalling in neurovascular complications of diabetes
    Authors:
    Jarosławska J, Kordas B, Milowski T, Juranek JK
    Academic press:
    European Journal of Neuroscience (rok: 2024, tom: 59 (10), strony: 2628-2645), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/ejn.16310 - link to the publication
  7. A mouse model of uterine exposure to long-term hyperglycemia and a high-fat diet
    Authors:
    Zglejc-Waszak K, Korytko A, Pomianowski A, Wojtkiewicz J, Wąsowicz K, Juranek JK
    Academic press:
    Animal Science Papers and Reports (rok: 2024, tom: 4 (2024), strony: 203-216), Wydawca: Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, Jastrzębiec, Poland
    Status:
    Published
    DOI:
    10.2478/aspr-2023-0031 - link to the publication
  8. The receptor for advanced glycation end products and its ligands expression in OVE26 diabetic sciatic nerve during the development of length-dependent neuropathy
    Authors:
    Zglejc-Waszak Kamila, Schmidt Ann M., Juranek Judyta.
    Academic press:
    Neuropathology (rok: 2023, tom: 43(1), strony: 84-94), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/neup.12852 - link to the publication
  1. The effect of type 1 diabetes on lumbar spinal cord transcriptome
    Authors:
    K. Zglejc-Waszak, A. Korytko, M. Banach, J. Juranek
    Conference:
    58th EASD Annual Meeting of the European Association for the Study of Diabetes (rok: 2022, ), Wydawca: SpringerNature (Diabetologia)
    Data:
    konferencja 19-23 Września 2022
    Status:
    Published
  2. Comparing Technical and Biological Repetitions in the Morphometric Analysis of Peripheral Nerves in Diabetic Neuropathy
    Authors:
    Kordas B, Zglejc-Waszak K, Juranek J
    Conference:
    13th Neuronus Neuroscience Forum (rok: 2024, ), Wydawca: NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY, Polish Academy of Sciences
    Data:
    konferencja 25-27 Kwietnia 2024
    Status:
    Published
  3. The effect of type 1 diabetes and high fat diet on the expression of receptor for advanced glycation end-product
    Authors:
    Zglejc-Waszak K, Korytko A, Wojtkiewicz J, Wąsowicz K, Juranek J
    Conference:
    28th CONGRESS OF THE POLISH PHYSIOLOGICAL SOCIETY (rok: 2021, ), Wydawca: Polish Physiological Society
    Data:
    konferencja 15-17 Września 2021
    Status:
    Published

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