Towards experimental pharmacology of endothelium in vivo based on multiparameter method of the assessment of vascular endothelial function in mice with the use of MR imaging techniques
2016/23/N/NZ5/00595
Keywords
Descriptors
- NZ5_5: Diagnostyka chorób człowieka
- NZ4_4: Patofizjologia ogólna
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 12 – announced on 2016-09-15
- Amount awarded
- 99 900 PLN
- Project start date
- 2017-07-17
- Project end date
- 2019-07-16
- Project duration
- 24 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Laptop. Cost: 5 100 PLN
Information in the final report
Publication in academic press/journals (3)
-
Degradation of Glycocalyx and Multiple Manifestations of Endothelial Dysfunction Coincide in the Early Phase of Endothelial Dysfunction Before Atherosclerotic Plaque Development in Apolipoprotein E/Low-Density Lipoprotein Receptor-Deficient Mice
- Authors:
- Bar A, Targosz-Korecka M, Suraj J, Proniewski B, Jasztal A, Marczyk B, Sternak M, Przybyło M, Kurpińska A, Walczak M, Kostogrys RB, Szymonski M, Chlopicki S.
- Academic press:
- Journal of the American Heart Association (year: 2019, volume: 8(6), pages: PMC6475045), Publisher: John Wiley & Sons on behalf of the American Heart Association (United States)
- Status:
- Published
- DOI:
- 10.1161/JAHA.118.011171 – link to the publication
-
The Deletion of Endothelial Sodium Channel α (αENaC) Impairs Endothelium-Dependent Vasodilation and Endothelial Barrier Integrity in Endotoxemia in Vivo
- Authors:
- Sternak M, Bar A, Adamski MG, Mohaissen T, Marczyk B, Kieronska A, Stojak M, Kus K, Tarjus A, Jaisser F, Chlopicki S
- Academic press:
- Frontiers in Pharmacology (year: 2018, volume: 9, pages: 178), Publisher: Frontiers Media
- Status:
- Published
- DOI:
- 10.3389/fphar.2018.00178 – link to the publication
-
Vitamin K2-MK-7 improves nitric oxide-dependent endothelial function in ApoE/LDLR-/- mice.
- Authors:
- Bar A, Kuś K, Manterys A, Proniewski B, Sternak M, Przyborowski K, Moorlag M, Sitek B, Marczyk B, Jasztal A, Skórka T, Franczyk-Żarów M, Kostogrys R, Chlopicki S.
- Status:
- Accepted for publication