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Bioactive compounds of Aronia melanocarpa berries and their potential anti-inflammatory and anti-atherosclerotic activity.

2015/17/B/NZ7/03089

Keywords

Descriptors

  • NZ7_12: Prewencja chorób człowieka
  • ST4_3: Metody spektroskopowe i spektrometryczne
  • ST4_1: Chemia fizyczna

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Iwona Wawer

Number of co-investigators in the project: 8

Call

OPUS 9 – announced on 2015-03-16

Amount awarded
783 080 PLN
Project start date
2016-02-18
Project end date
2020-08-17
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Analityczny system wysokosprawnej chromatografii cieczowej (HPLC). Cost: 180 000 PLN
  2. Autosampler do spektrometru EPR. Cost: 78 165 PLN
  3. Detektor do chromatografu HPLC. Cost: 49 890 PLN
  4. Liofilizator laboratoryjny. Cost: 50 000 PLN
  5. MNova, Mestrelab Research (oprogramowanie). Cost: 4 500 PLN
  6. Myjka ultradźwiękowa.
  7. Origin Pro, OriginLab (oprogramowanie). Cost: 5 000 PLN
  8. Rezonator do spektrometru EPR. Cost: 50 000 PLN
  9. Wyparka rotacyjna sterowana elektronicznie z systemem próżniowym.
  10. Wytrząsarka typu Vortex. Cost: 1 100 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Aronia melanocarpa Fruits as a Rich Dietary Source of Chlorogenic Acids and Anthocyanins: 1H-NMR, HPLC-DAD, and Chemometric Studies

    Authors:
    Agnieszka Zielińska, Paweł Siudem, Katarzyna Paradowska, Małgorzata Gralec, Sławomir Kaźmierski, Iwona Wawer
    Academic press:
    Molecules (year: 2020, volume: 25, pages: 3234 - 3250), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25143234 – link to the publication

  2. Aronia melanocarpa berries: phenolics composition and antioxidant properties changes during fruit development and ripening

    Authors:
    Małgorzata Gralec, Iwona Wawer, Katarzyna Zawada
    Academic press:
    Emirates Journal of Food and Agriculture (year: 2019, volume: 31, pages: 214-221), Publisher: United Arab Emirates University
    Status:
    Published
    DOI:
    10.9755/ejfa.2019.v31.i3.192 – link to the publication

  3. Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity

    Authors:
    Agnieszka Zielińska, Dorota Bryk, Katarzyna Paradowska, Iwona Wawer
    Academic press:
    Pol. J. Food Nutr. Sci (year: 2020, volume: 70 (4), pages: 409-418), Publisher: Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.31883/pjfns/130255 – link to the publication

Articles in post-conference publications (5)

  1. Profile of chlorogenic acids during growth of Aronia melanocarpa fruits, determined by HPLC-DAD and 1H NMR

    Authors:
    K. Paradowska, A. Zielinska, P. Siudem, V. Kowalska
    Conference:
    2nd Food Chemistry Conference: Shaping the Future of Food Quality, Safety, Nutrition and Health (year: 2019, pages: 58), Publisher: Elsevier
    Date:
    conference 43725
    Status:
    Published

  2. HPLC-DAD i 1H NMR w badaniu zmienności kwasu chlorogenowego i neochlorogenowego podczas wzrostu owoców Aronia melanocarpa

    Authors:
    Katarzyna Paradowska, Agnieszka Zielińska, Paweł Siudem, Violetta Kowalska, Iwona Wawer
    Conference:
    Ogólnopolska Konferencja Naukowa Pierwotne i wtórne metabolity roślin i grzybów (year: 2020, pages: 47-48), Publisher: Fundacja na rzecz promocji nauki i rozwoju TYGIEL
    Date:
    conference 28,02
    Status:
    Published

  3. The variation of the polyphenol content of Aronia melanocarpa cultivated in Poland due to geographical region and collection time

    Authors:
    Katarzyna Zawada, Agnieszka Zielińska, Natalia Dobros, Iwona Wawer
    Conference:
    5th International Conference and Workshop. Plant - The source of research material (year: 2017, pages: 172), Publisher: Lubelskie Towarzystwo Wspierania Nauk Farmaceutycznych
    Date:
    conference 21-24.06
    Status:
    Published

  4. The variation in the antioxidant activity of Aronia melanocarpa cultivated in Poland due to geographical region and collection time

    Authors:
    Katarzyna Zawada, Agnieszka Zielińska, Natalia Dobros, Iwona Wawer
    Conference:
    V Forum EMR-PL (year: 2018, pages: 68), Publisher: Wydział Chemii, Uniwersytet Wrocławski
    Date:
    conference 5-8 Czerwca
    Status:
    Published

  5. Aronia melanocarpa Fruits as a Dietary Source of bioactive compounds: 1H NMR, HPLC-DAD, and Chemometric Studies

    Authors:
    Pawel Siudem
    Conference:
    Exploring the molecular diversity of grape, a source of natural ingredients (year: 2020, pages: 16), Publisher: Le Studium Loire Valley Institute for Advanced Studies
    Date:
    conference 44168
    Status:
    Published

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