Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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An application of novel approaches in the search for linkage of genetic defects and exponents of immune dysregulation resulting in selective IgA deficiency in the pathogenesis of type 1 diabetes.

2012/05/B/NZ5/01898

Keywords:

type 1 diabetes Selective IgA Deficiency SIgA immune dysregulation cytokines mutation TACI and ICOS gene genetic variability antibodies HLA class II MLPA haplotypes

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, I Katedra Pediatrii, Klinika Pediatrii, Onkologii, Hematologii i Diabetologii Uniwersytetu Medycznego w Łodzi

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Izabela Klich 

Number of co-investigators in the project: 5

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 462 300 PLN

Project start date (Y-m-d): 2013-01-25

Project end date (Y-m-d): 2016-01-24

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Clinical heterogeneity among pediatric patients with autoimmune type 1 diabetes stratified by immunoglobulin deficiency
    Authors:
    Anna Hogendorf, Małgorzata Szymańska, Joanna Krasińska, Anna Baranowska-Jaźwiecka, Marta Ancuta, Anna Charubczyk, Krystyna Wyka, Izabela Drozdz, Magdalena Sokolowska-Gadoux, Joanna Zarebska, Arkadiusz Michalak, Agnieszka Szadkowska, Przemysława Jarosz-Chobot , Wojciech Młynarski
    Academic press:
    Pediatr Diabetes (rok: 2021, tom: nie dotyczy, strony: 45301), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1111/pedi.13208 - link to the publication
  2. COULD SEMAPHORIN 4D AND DKK-1 BE NEW METABOLIC BONE MARKERS IN PATIENTS WITH TYPE 1 DIABETES?
    Authors:
    Pyziak-Skupień Aleksandra, Szymańska Małgorzata, Jeziorny Krzysztof, Wyka Krystyna, Drozdz Izabela, Jarosz-Chobot Przemysława, Borowiec Maciej, Szadkowska Agnieszka, Zmysłowska Agnieszka
    Academic press:
    Journal of Pediatric Endocrinology and Metabolism (tom: brak, strony: brak), Wydawca: DE GRUYTER
    Status:
    Submitted